Patents by Inventor Gert Streissle

Gert Streissle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5646121
    Abstract: The present invention relates to novel pseudopeptides with antiviral activity of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to a process for their preparation, and to their use as antiviral agents, especially against cytomegaloviruses.
    Type: Grant
    Filed: September 7, 1994
    Date of Patent: July 8, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter Habich, Thomas-J. Schulze, Jurgen Reefschlager, Jutta Hansen, Rainer Neumann, Gert Streissle, Arnold Paessens
  • Patent number: 5633231
    Abstract: The present invention relates to valine-containing, substituted pseudopeptides of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to processes for their preparation, and to their use as anti-viral agents, in particular against cytomegaloviruses.
    Type: Grant
    Filed: September 7, 1994
    Date of Patent: May 27, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter Habich, Thomas J. Schulze, Jurgen Reefschlager, Jutta Hansen, Rainer Neumann, Gert Streissle, Arnold Paessens
  • Patent number: 5492896
    Abstract: The invention relates to new pseudopeptides having an antiviral action, oft he general formula (I) ##STR1## with the meanings given in the description for the substituents, to a process for their preparation and to their use as antiviral agents, in particular against cytomegaloviruses.
    Type: Grant
    Filed: February 15, 1994
    Date of Patent: February 20, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter Habich, Michael Matzke, Klaus Frobel, Thomas Henkel, Hartwig Muller, Karl-Heinz Weber, Jurgen Reefschlager, Gert Streissle, Jutta Hansen, Rainer Neumann, Arnold Paessens
  • Patent number: 4855283
    Abstract: Compounds of the formula ##STR1## in which R.sup.1 denotes hydrogen or a saturated or singly or multiply unsaturated alkyl radical having up to 50 carbon atoms,X represents --CH.sub.2 --, --O-- or --NH--,R.sup.2 denotes hydrogen or a saturated or singly or multiply unsaturated alkyl radical having up to 50 carbon atoms,R.sup.3, R.sup.4 and R.sup.5, independently of one another, denotes hydrogen or acyl--CO--R.sup.6, R.sup.6 being an alkyl radical having up to 10 carbon atoms,R.sup.7 denotes hydrogen, C.sub.1 -C.sub.7 -alkyl-, hydroxymethyl, 1-hydroxyethyl, mercaptomethyl, 2-(methylthio)-ethyl, 3-aminopropyl, 3-ureidopropyl, 3-guanidyl-propyl, 4-aminobutyl, carboxymethyl, carbamylmethyl, 2-carboxyethyl, 2-carbamoylethyl, benzyl, 4-hydroxybenzyl, 3-indolylmethyl or 4-imidazolylmethyl, andR.sup.8 represents hydrogen or methyl, andR.sup.9 represents hydrogen, acetyl, benzoyl, trichloroacetyl, trifluoroacetyl, methoxycarbonyl, t-butyloxycarbonyl or benzyloxycarbonyl andR.sup.7 and R.sup.8 together can denote --CH.
    Type: Grant
    Filed: June 16, 1986
    Date of Patent: August 8, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Oswald Lockhoff, Yutaka Hayauchi, Peter Stadler, Klaus G. Stunkel, Gert Streissle, Arnold Paessens, Volker Klimetzek, Hans-Joachim Zeiler, Karl G. Metzger, Hein-Peter Kroll, Helmut Brunner, Klaus Schaller
  • Patent number: 4686208
    Abstract: Compounds of the formula ##STR1## in which R.sup.1 represents an optionally substituted, straight-chain or branched, saturated, monounsaturated or polyunsaturated alkyl radical, an optionally substituted, saturated or one- or polyunsaturated cycloalkyl radical or an optionally substituted aryl radical or aralkyl radical,X represents CH.sub.2, O, S, NH or N-alkyl with up to 20 C atoms,R.sup.2 has the meaning of R.sup.1, and can represent hydrogen if X denotes CH.sub.2, the radicals R.sup.3 independently of one another represent hydrogen, an acyl radical or alkyl radical with in each case up to 20 C atoms, a silyl radical and/or a phosphoric acid or phosphoric acid ester radical andR.sup.4 denotes hydrogen, methyl or --CH.sub.2 --OR.sup.3, with the proviso that one of the radicals R.sup.3 always represents a phosphoric acid or phosphoric acid ester radical, which stimulate a patient's immune system and are thereby effective in combating viral disease and bacterial infection.
    Type: Grant
    Filed: November 21, 1984
    Date of Patent: August 11, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Oswald Lockhoff, Bernd-Wieland Kruger, Peter Stadler, Arnold Paessens, Gert Streissle, Peter Taylor, Hans-Joachim Zeiler, Karl-Georg Metzger
  • Patent number: 4668660
    Abstract: The invention relates to hydroxyethylazolyl derivatives, defined herein by formula (I) and particularly to the use of said derivatives for the treatment of viral infections.
    Type: Grant
    Filed: April 10, 1984
    Date of Patent: May 26, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Arnold Paessens, Gert Streissle, Manfred Plempel, Karl H. B/u/ chel, Hans-Ludwig Elbe, Graham Holmwood, Udo Kraatz, Erik Regel
  • Patent number: 4564622
    Abstract: The invention relates to 2-(4-chlorophenoxymethyl)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-2-butanol and its use for treating herpes viral infections.
    Type: Grant
    Filed: April 29, 1985
    Date of Patent: January 14, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gert Streissle, Manfred Plempel, Arnold Paessens, Graham Holmwood, Karl H. Buchel
  • Patent number: 4308263
    Abstract: The invention relates to phosphonoformic acid hydrazide compounds of the formula ##STR1## and salts thereof wherein R represents a hydrogen atom or a C.sub.1 -C.sub.6 -alkyl radical. The compounds are useful as antiviral agents, particularly against herpes viruses.Also included in the invention are processes for preparing said phosphonoformic acid hydrazide compounds, compositions and medicaments containing said phosphonoformic acid hydrazide compounds and methods for the use of said compounds and compositions.
    Type: Grant
    Filed: June 20, 1980
    Date of Patent: December 29, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hermann Oediger, Folker Lieb, Gert Streissle