Patents by Inventor Ghaith BAKDASH

Ghaith BAKDASH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240000861
    Abstract: The disclosure relates to therapeutic compositions comprising isolated bacteria useful in the treatment of ulcerative colitis or Crohn's disease. Related methods and uses are also disclosed.
    Type: Application
    Filed: October 4, 2021
    Publication date: January 4, 2024
    Inventors: Ghaith Bakdash, Simon Harris, Dominika Klisko, Trevor Lawley, Seánín McCluskey, Thomas Mitchell, Anne Neville, Amy Popple, Oliver Rimington, Matthew Robinson, Michael Romanos, Adam Wilkinson
  • Publication number: 20230346850
    Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.
    Type: Application
    Filed: August 30, 2022
    Publication date: November 2, 2023
    Inventors: Matthew Robinson, Trevor Lawley, Michael Romanos, Kevin Vervier, Simon Harris, Ghaith Bakdash, Amy Popple, Dominika Klisko
  • Patent number: 11612644
    Abstract: The invention pertains to a cell population for use in treating cancer in a patient, comprising CD1c (BDCA-1)+/CD19? dendritic cells, wherein CD1c(BDCA-1)+/CD19? dendritic cells are depleted for CD1c (BDCA-1)+/CD19?/CD14+ cells.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: March 28, 2023
    Assignee: MILTENYI BIOTEC B.V. & CO. KG
    Inventors: Jolanda De Vries, Carl Figdor, Ghaith Bakdash
  • Patent number: 11439671
    Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: September 13, 2022
    Assignee: Microbiotica Limited
    Inventors: Matthew Robinson, Trevor Lawley, Michael Romanos, Kevin Vervier, Simon Harris, Ghaith Bakdash, Amy Popple, Dominika Klisko
  • Publication number: 20210275602
    Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.
    Type: Application
    Filed: May 19, 2021
    Publication date: September 9, 2021
    Inventors: Matthew Robinson, Trevor Lawley, Michael Romanos, Kevin Vervier, Simon Harris, Ghaith Bakdash, Amy Popple, Dominika Klisko
  • Patent number: 10925944
    Abstract: The invention pertains to a cell population for use in treating cancer in a patient, comprising CD1c(BDCA-1)+/CD19? dendritic cells, wherein CD1c(BDCA-1)+/CD19? dendritic cells are depleted for CD1c(BDCA-1)+/CD19?/CD14+ cells.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: February 23, 2021
    Assignee: MILTENYI BIOTEC B.V. & CO. KG
    Inventors: Jolanda De Vries, Carl Figdor, Ghaith Bakdash
  • Publication number: 20210038702
    Abstract: The invention pertains to a cell population for use in treating cancer in a patient, comprising CD1c (BDCA-1)+/CD19? dendritic cells, wherein CD1c(BDCA-1)+/CD19? dendritic cells are depleted for CD1c (BDCA-1)+/CD19?/CD14+ cells.
    Type: Application
    Filed: July 22, 2020
    Publication date: February 11, 2021
    Applicant: MILTENYI BIOTEC B.V. & CO. KG
    Inventors: Jolanda DE VRIES, Carl FIGDOR, Ghaith BAKDASH
  • Publication number: 20170258882
    Abstract: The invention pertains to a cell population for use in treating cancer in a patient, comprising CD1c (BDCA-1)+/CD19? dendritic cells, wherein CD1c(BDCA-1)+/CD19? dendritic cells are depleted for CD1c (BDCA-1)+/CD197CD14+ cells.
    Type: Application
    Filed: September 10, 2015
    Publication date: September 14, 2017
    Applicant: MILTENYI BIOTEC GMBH
    Inventors: Jolanda DE VRIES, Carl FIGDOR, Ghaith BAKDASH