Patents by Inventor Ghislain Schyns

Ghislain Schyns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SPORE SURFACE DISPLAYS OF BIOACTIVE MOLECULES
    Publication number: 20100055244
    Abstract: This invention discloses novel bacterial spore systems. It has now been found surprisingly that under certain conditions bacterial spore systems can be used in the food and feed industry, preferably in animal feeding and as biohybrid material. More precisely applicant has found the following: Genetically modified or genetically engineered viable spore systems expressing bioactive polypeptides, for example bacteriocins and/or enzymatically active feed enzymes, at the spore surface, have a great potential use in animal feeding. Further, it has been found that genetically modified or “genetically engineered inert spore systems expressing affinity ligands or immobilized enzymes at the surface have a great potential use in biocatalysis and in the construction of biocatalytic films.
    Type: Application
    Filed: August 9, 2007
    Publication date: March 4, 2010
    Inventors: Adriano O. Henriques, Ghislain Schyns, Thibaut José Wenzel, Sebastian Potot
  • Thiamin production by fermentation
    Publication number: 20090233296
    Abstract: The present invention provides a method for producing thiamin products using a microorganism containing a mutation that causes it to overproduce and release thiamin products into the medium. Biologically pure cultures of the microorganisms and isolated polynucleotides containing the mutations are also provided. In addition, methods for detecting a pathogenic microorganism in a clinical sample, assays for identifying an antibiotic, as well as, antibiotics identified by such assays are provided.
    Type: Application
    Filed: March 2, 2009
    Publication date: September 17, 2009
    Inventors: Markus G. Goese, John B. Perkins, Ghislain Schyns
  • Microbial production of COQ10
    Patent number: 7435571
    Abstract: The present Invention relates to enzymes involved in the Synthesis of Coenzyme Q-10, i.e., decaprenyl diphosphate (DPP) synthase and 4-hydroxybenzoate polyprenyltransferase, to isolated DNA encoding said enzymes and to methods for the microbial production of Coenzyme Q-10.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: October 14, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Markus Huembelin, Rual Lopez-Ulibarri, John B. Perkins, Ghislain Schyns
  • Thiamin production by fermentation
    Publication number: 20060127993
    Abstract: The present invention provides a method for producing thiamin products using a microorganism containing a mutation that causes it to overproduce and release thiamin products into the medium. Biologically pure cultures of the microorganisms and isolated polynucleotides containing the mutations are also provided. In addition, methods for detecting a pathogenic microorganism in a clinical sample, assays for identifying an antibiotic, as well as, antibiotics identified by such assays are provided.
    Type: Application
    Filed: May 27, 2004
    Publication date: June 15, 2006
    Inventors: Markus Goese, John Perkins, Ghislain Schyns
  • Microbial production of coq10
    Publication number: 20060088920
    Abstract: The present Invention relates to enzymes involved in the Synthesis of Coenzyme Q-10, i.e., decaprenyl diphosphate (DPP) synthase and 4-hydroxybenzoate polyprenyltransferase, to isolated DNA encoding said enzymes and to methods for the microbial production of Coenzyme Q-10.
    Type: Application
    Filed: February 13, 2004
    Publication date: April 27, 2006
    Inventors: Markus Huembelin, Rual Lopez-Ulibarri, John Perkkins, Ghislain Schyns