Abstract: A screw for snugly-fitted tightening pairs, of the type having a lobate head or a lobate-socket head (31), in which each lobe (37) is formed of one face (37') directed in a substantially circumferential manner and two other substantially parallel faces (35, 36) directed inwardly of the screw; said screw is provided with a reaction surface (33) with a tightening wrench (32). The portions of said reaction surface (33) included between two adjacent lobes are comprised each of a pair of faces (38, 39) inclined to each other to form an angle concave towards the outside of the screw, so as to constitute a reaction surface with a wrench of a polygonal profile. Such a screw can be operated to advantage either with the polygonal wrenches of the known art, or with an innovatory mating wrench of a lobate configuration.