Patents by Inventor Gilbert Lavielle

Gilbert Lavielle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100168150
    Abstract: Compound of formula (I): wherein: R1, R2, R3, R4, R5, R80, R90, R81, R91, Alk, Alk?, X, X? and G are as defined in the description. Medicinal products containing the same which are useful in the treatment of cancer diseases.
    Type: Application
    Filed: August 4, 2006
    Publication date: July 1, 2010
    Applicant: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Patrick Hautefaye, Alain Pierre, John Hickman, Stephane Leonce
  • Publication number: 20100168149
    Abstract: Compound of formula (I): wherein: R1, R2, R3, R4, R5, R80, R90, R81, R91, Alk and G are as defined in the description. Medicinal products containing the same which are useful in the treatment of cancer diseases.
    Type: Application
    Filed: August 4, 2006
    Publication date: July 1, 2010
    Inventors: Gilbert Lavielle, Patrick Hautefaye, Alain Pierre, John Hickman, Stephane Leonce
  • Patent number: 7618955
    Abstract: The present invention relates to a new combination of an antithrombotic and aspirin and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: November 17, 2009
    Assignee: Les Laboratoires Servier
    Inventors: Tony Verbeuren, Gilbert Lavielle, Bernard Cimetiere, Marie-Odile Vallez
  • Publication number: 20090075976
    Abstract: The present invention relates to the association of an anti-atherothrombotic and an angiotensin-converting enzyme inhibitor (ACEI), and also to pharmaceutical compositions containing them, and to methods of treating vascular complications associated with diabetes, with atherothrombotic diseases, with hyperlipidaemia, with hypertension, with chronic venous diseases, with inflammation, with metabolic syndrome associated with obesity, or with cancer, with such association.
    Type: Application
    Filed: September 8, 2008
    Publication date: March 19, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Tony Verbeuren, Patricia Sansilvestri-Morel, Alain Rupin, Marie-Odile Vallez, Marie-Dominique Fratacci, Laurence Lerond, Gilbert Lavielle
  • Publication number: 20070238785
    Abstract: The present invention relates to the use of a specific antagonist of TP receptors in obtaining medicaments intended for the treatment of vascular disorders in patients having had a previous cerebral vascular accident, especially for reducing cerebrovascular and cardiovascular events in patients having had a previous cerebral ischaemic accident (CIA) or transitory ischaemic attack (TIA).
    Type: Application
    Filed: April 5, 2007
    Publication date: October 11, 2007
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Marie-Dominique Fratacci, Agnes De Cordoue, Laurence Lerond, Tony Verbeuren, Alain Rupin, Gilbert Lavielle
  • Patent number: 7053108
    Abstract: A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, and R3 represents hydrogen, or R1 represents hydrogen, and R2 and R3 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, its enantiomers, diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicaments.
    Type: Grant
    Filed: March 30, 2004
    Date of Patent: May 30, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert
  • Patent number: 7026357
    Abstract: Compound of formula (I): and medicinal products containing the same are useful as dual ?2/5-HT2c antagonist receptors.
    Type: Grant
    Filed: June 7, 2004
    Date of Patent: April 11, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Patent number: 6998403
    Abstract: A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, and R3 and R4 represent hydrogen, or R1 and R4 represent hydrogen and R2 and R3 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, or R1 and R2 represent hydrogen and R3 and R4 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, addition salts thereof with a pharmaceutically acceptable acid or base, and methods of treating conditions susceptible to ?2-AR/5-HT2C antagonists.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: February 14, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert, Benjamin Di Cara
  • Publication number: 20050143354
    Abstract: The present invention relates to a new combination of an antithrombotic and aspirin and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: April 4, 2003
    Publication date: June 30, 2005
    Inventors: Tony Verbeuren, Gilbert lavielle, Cimetiere Bernard, Marie-Odile Vallez
  • Publication number: 20050059675
    Abstract: A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, and R3 and R4 represent hydrogen, or R1 and R4 represent hydrogen and R2 and R3 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, or R1 and R2 represent hydrogen and R3 and R4 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, addition salts thereof with a pharmaceutically acceptable acid or base, and methods of treating conditions susceptible to ?2-AR/5-HT2C antagonists.
    Type: Application
    Filed: August 25, 2004
    Publication date: March 17, 2005
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert, Benjamin Di Cara
  • Publication number: 20040224993
    Abstract: Compound of formula (I): 1
    Type: Application
    Filed: June 7, 2004
    Publication date: November 11, 2004
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Publication number: 20040192736
    Abstract: A compound of formula (I): 1
    Type: Application
    Filed: March 30, 2004
    Publication date: September 30, 2004
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert
  • Patent number: 6784183
    Abstract: Compounds of formula (I): and medicinal products containing the same which are useful as dual &agr;2/5-HT2c antagonists.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: August 31, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Patent number: 6759421
    Abstract: A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, and R3 represents hydrogen, or R1 represents hydrogen, and R2 and R3 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, its enantiomers, diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicaments.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: July 6, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert
  • Patent number: 6747032
    Abstract: Compound of formula (I): wherein: R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen atom, a halogen atom or a group selected from alkyl, alkoxy, polyhaloalkyl, hydroxy, cyano, nitro and amino,  or R1 with R2, R2 with R3, or R3 with R4, together with the carbon atoms carrying them, form an optionally substituted benzene ring or an optionally substituted heteroaromatic ring, X represents an oxygen atom or a methylene group, A represents an alkylene chain,  represents an optionally substituted, unsaturated, nitrogen-containing heterocycle and R5 represents an alkyl group, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid, a medicinal products containing the same are useful as a double &agr;2/5-HT2c antagonist.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: June 8, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Thierry Dubuffet, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Patent number: 6699876
    Abstract: Compound of formula (I): wherein: n is 0, 1 or 2, R1 represents (C3-C11)cycloalkyl or (C3-C11)cycloalkylalkyl, R2, R3, R4 and R5 are selected from hydrogen, halogen, alkyl, alkenyl, alkynyl, perhaloalkyl, cycloalkyl, cycloalkylalkyl, hydroxy, hydroxyalkyl, alkoxy, alkoxyalkyl, alkoxycarbonyl, acyloxy, carboxy, nitro, cyano, aminocarbonyl (optionally substituted), and the groups (CH2)p—NaRb and —O—C(O)—N—RaRb, with p, Ra and Rb being as defined in the description, or two adjacent groups R2, R3, R4 and R5 together form a group —O—(CH2)t—O, t being integer from 1 to 3, R60, R70n, R80 and R90 represent a hydrogen atom, a hydroxy group, an alkoxy group, or an O—(CO)—X or O—(CO)—NXW group as defined in the description, R61, R71n, R81, and R91 represent a hydrogen atom, alkyl, alkenyl or alkynyl, or taken in pairs together form a bond or an oxirane group, or two groups together form an oxo group.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: March 2, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Patrick Hautefaye, Alain Pierre, Ghanem Atassi, John Hickman, Bernard Cimetiere
  • Publication number: 20030199555
    Abstract: A compound of formula (I): 1
    Type: Application
    Filed: March 27, 2003
    Publication date: October 23, 2003
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert
  • Patent number: 6589956
    Abstract: A compound of formula (I): wherein: Ra represents a hydroxy, alkoxy, aryloxy or arylalkyloxy group, A represents a CH group or a nitrogen atom, in which case R1 is as defined in the description, or R1—A together represent an oxygen atom or a group, wherein R3 and R4 are as defined in the description, R2 being a hydrogen atom or an alkyl group, Rb and Rc, which may be identical or different, each represents a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, a hydroxy group or a trihaloalkyl group, n is an integer of from 2 to 6 inclusive, m and p are integers of from 0 to 6 inclusive, its enantiomers, diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful as a TXA2 receptor antagonist and 5-HT2 receptor antagonist.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: July 8, 2003
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Bernard Cimetiere, Tony Verbeuren, Serge Simonet, Christine Vayssettes-Courchay
  • Publication number: 20030109533
    Abstract: A compound of formula (I): 1
    Type: Application
    Filed: July 12, 2002
    Publication date: June 12, 2003
    Inventors: Gilbert Lavielle, Bernard Cimetiere, Tony Verbeuren, Serge Simonet, Christine Vayssettes-Courchay
  • Publication number: 20030105109
    Abstract: Compound of formula (I): 1
    Type: Application
    Filed: November 20, 2002
    Publication date: June 5, 2003
    Inventors: Gilbert Lavielle, Patrick Hautefaye, Alain Pierre, Ghanem Atassi, John Hickman, Bernard Cimetiere