Publication number: 20060069110
Abstract: The present invention relates to pyridines, pyrimidines and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic ? cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs.
Type:
Application
Filed:
September 27, 2005
Publication date:
March 30, 2006
Inventors:
Denise Andersen, Catherine Chang, James Falsey, Michael Frohn, Fang-Tsao Hong, Hongyu Liao, Longbin Liu, Patricia Lopez, Daniel Retz, Gilbert Rishton, Robert Rzasa, Aaron Siegmund, Seifu Tadesse, Nuria Tamayo, Christopher Tegley