Patents by Inventor Gilles DeMichelis

Gilles DeMichelis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Particles coated with granulated crystalline ibuprofen
    Patent number: 6951657
    Abstract: The invention concerns coated particles based on granulated microcrystals of ibuprofen, its pharmaceutically acceptable isomers and salts, characterized in that they comprise a coating obtained in a fluidized bed apparatus with a hydroalcoholic dispersion consisting of a mixture comprising (A) 5 to 50% by weight of ethylcellulose relative to ibuprofen; (B) 10 to 60% by weight of hydroxypeopylmethylcellulose relative to the ethylcellulose; and (C) 1 to 40% by weight of silica with antistatic and permeabilizing properties relative to the ethylcellulose, the resulting coating, whereof at least one of the constituents can be used for granulating the ibuprofen microcrystals resulting in said particles, thereby masking the unpleasant taste of ibuprofen and significantly reducing its irritating effect on the throat after deglutition and substantially immediate release of ibuprofen when the particles are placed in an aqueous medium.
    Type: Grant
    Filed: November 3, 1999
    Date of Patent: October 4, 2005
    Assignee: Laboratoires des produits Ethiques Ethypharm SA
    Inventors: Jean-Marc Zuccarelli, Charles André Chauveau, Gilles DeMichelis, Karine Jean
  • Process for manufacturing coated gabapentin or pregabalin particles
    Patent number: 6488964
    Abstract: A process for manufacturing coated particles of &ggr;-aminobutyric acid analogue, whose lactam content by weight relative to the weight of &ggr;-aminobutyric acid analogue is less than 0.5% is disclosed. The process is characterized in that a coating solution of at least one polymer in an organic solvent is sprayed onto the particles of &ggr;-aminobutyric acid analogue.
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: December 3, 2002
    Assignee: Societe Laboratoires des Products Ethiques - Ethypharm
    Inventors: Etienne Bruna, Edouard Gendrot, Charles Chauveau, Alain-Gilles Demichelis
  • Process for manufacturing coated gabapentin or pregabalin particles
    Publication number: 20020012679
    Abstract: A process for manufacturing coated particles of &ggr;-aminobutyric acid analogue, whose lactam content by weight relative to the weight of &ggr;-aminobutyric acid analogue is less than 0.5% is disclosed. The process is characterized in that a coating solution of at least one polymer in an organic solvent is sprayed onto the particles of &ggr;-aminobutyric acid analogue.
    Type: Application
    Filed: February 5, 2001
    Publication date: January 31, 2002
    Applicant: Societe Laboratoires des Produits Ethiques - Ethypharm
    Inventors: Etienne Bruna, Edouard Gendrot, Charles Chauveau, Alain-Gilles Demichelis
  • Multiparticulate tablet disintegrating in less than 40 seconds in the mouth
    Patent number: 6106861
    Abstract: The invention relates to a rapidly disintegratable multiparticulate tablet which disintegrates in the mouth in less than 40 seconds and which comprises an excipient and an active ingredient in the form of microcrystals coated with a coating agent.
    Type: Grant
    Filed: December 5, 1997
    Date of Patent: August 22, 2000
    Assignee: Laboratoires Prographarm
    Inventors: Charles Chauveau, Edouard Gendrot, Alain Gilles Demichelis, Noureddine Nouri