Patents by Inventor Gina PASTINO

Gina PASTINO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating major depressive disorder
    Patent number: 11957645
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Grant
    Filed: March 30, 2023
    Date of Patent: April 16, 2024
    Assignee: CLEXIO BIOSCIENCES LTD.
    Inventors: Elena Kagan, Gina Pastino
  • Method Of Treating Major Depressive Disorder
    Publication number: 20240091174
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 21, 2024
    Inventors: Elena Kagan, Gina Pastino
  • Method Of Treating Major Depressive Disorder
    Publication number: 20240074992
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Application
    Filed: November 14, 2023
    Publication date: March 7, 2024
    Inventors: Elena Kagan, Gina Pastino
  • METHOD OF TREATING MAJOR DEPRESSIVE DISORDER
    Publication number: 20240074991
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Application
    Filed: November 8, 2023
    Publication date: March 7, 2024
    Inventors: Elena KAGAN, Gina PASTINO
  • Method of treating major depressive disorder
    Patent number: 11865088
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: January 9, 2024
    Assignee: CLEXIO BIOSCIENCES LTD.
    Inventors: Elena Kagan, Gina Pastino
  • METHOD OF TREATING MAJOR DEPRESSIVE DISORDER
    Publication number: 20230233487
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Application
    Filed: March 30, 2023
    Publication date: July 27, 2023
    Inventors: Elena KAGAN, Gina PASTINO
  • METHOD OF TREATING MAJOR DEPRESSIVE DISORDER
    Publication number: 20220125742
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Inventors: Elena Kagan, Gina Pastino
  • Method of treating major depressive disorder
    Patent number: 11253487
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: February 22, 2022
    Assignee: CLEXIO BIOSCIENCES LTD.
    Inventors: Elena Kagan, Gina Pastino
  • METHOD OF TREATING MAJOR DEPRESSIVE DISORDER
    Publication number: 20210228505
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Application
    Filed: April 13, 2021
    Publication date: July 29, 2021
    Inventors: Elena Kagan, Gina Pastino
  • Compositions and methods for treating insomnia
    Patent number: 11026944
    Abstract: In the present invention, compound such as (1R,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl) cyclopropanecarboxamide have been found to be potent orexin receptor antagonists, and may be useful in the treatment of sleep disorders such as insomnia, as well as for other therapeutic uses.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: June 8, 2021
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Margaret Moline, Gina Pastino, Yurie Akimoto, Yasuhiro Zaima, Nobuya Suzuki, Nobuo Yoshida
  • Method Of Treating Post-Traumatic Stress Syndrome
    Publication number: 20210113494
    Abstract: The present disclosure provides methods for safe and efficacious administration of esketamine.
    Type: Application
    Filed: December 29, 2020
    Publication date: April 22, 2021
    Inventors: Elena Kagan, Gina Pastino, Esther Lukasiewicz-Hagai, Ari Gershon
  • COMPOSITIONS AND METHODS FOR TREATING INSOMNIA
    Publication number: 20200268754
    Abstract: In the present invention, compound such as (1R,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl) cyclopropanecarboxamide have been found to be potent orexin receptor antagonists, and may be useful in the treatment of sleep disorders such as insomnia, as well as for other therapeutic uses.
    Type: Application
    Filed: March 16, 2020
    Publication date: August 27, 2020
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Margaret MOLINE, Gina PASTINO, Yurie AKIMOTO, Yasuhiro ZAIMA, Nobuya SUZUKI, Nobuo YOSHIDA
  • Compositions and methods for treating insomnia
    Patent number: 10702529
    Abstract: In the present invention, compound such as (1R,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl) cyclopropanecarboxamide have been found to be potent orexin receptor antagonists, and may be useful in the treatment of sleep disorders such as insomnia, as well as for other therapeutic uses.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: July 7, 2020
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Margaret Moline, Gina Pastino, Yurie Akimoto, Yasuhiro Zaima, Nobuya Suzuki, Nobuo Yoshida
  • METHOD OF TREATING MAJOR DEPRESSIVE DISORDER
    Publication number: 20200147005
    Abstract: The present invention provides a method for safe and efficacious administration of esketamine.
    Type: Application
    Filed: October 4, 2019
    Publication date: May 14, 2020
    Inventors: Elena Kagan, Gina Pastino
  • COMPOSITIONS AND METHODS FOR TREATING INSOMNIA
    Publication number: 20190201399
    Abstract: In the present invention, compound such as (1R,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl)cyclopropanecarboxamide have been found to be potent orexin receptor antagonists, and may be useful in the treatment of sleep disorders such as insomnia, as well as for other therapeutic uses.
    Type: Application
    Filed: January 23, 2019
    Publication date: July 4, 2019
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Margaret MOLINE, Gina PASTINO, Yurie AKIMOTO, Yasuhiro ZAIMA, Nobuya SUZUKI, Nobuo YOSHIDA
  • Compositions and methods for treating insomnia
    Patent number: 10188652
    Abstract: In the present invention, compound such as (1R,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl) cyclopropanecarboxamide have been found to be potent orexin receptor antagonists, and may be useful in the treatment of sleep disorders such as insomnia, as well as for other therapeutic uses.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: January 29, 2019
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Margaret Moline, Gina Pastino, Yurie Akimoto, Yasuhiro Zaima, Nobuya Suzuki, Nobuo Yoshida
  • COMPOSITIONS AND METHODS FOR TREATING INSOMNIA
    Publication number: 20170252342
    Abstract: In the present invention, compound such as (1R,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl) cyclopropanecarboxamide have been found to be potent orexin receptor antagonists, and may be useful in the treatment of sleep disorders such as insomnia, as well as for other therapeutic uses.
    Type: Application
    Filed: October 21, 2015
    Publication date: September 7, 2017
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Margaret MOLINE, Gina PASTINO, Yurie AKIMOTO, Yasuhiro ZAIMA, Nobuya SUZUKI, Nobuo YOSHIDA