Patents by Inventor Giorgio Soldani
Giorgio Soldani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11738483Abstract: A method for making a biocompatible three-dimensional object includes delivering, using a delivery system, a biocompatible fluid substance comprising a plurality of particles towards a support body having a matrix surface to obtain a coating layer of predetermined thickness configured for coating the matrix surface, generating a relative movement with at least three degrees of freedom between the support body and the delivery system, and removing from the support body any surplus particles of the biocompatible fluid substance to make uniform the predetermined thickness of the coating layer. The support body is coated with the biocompatible fluid substance to obtain a three-dimensional object having an object surface corresponding to the matrix surface.Type: GrantFiled: February 28, 2022Date of Patent: August 29, 2023Assignee: S.M. SCIENZIA MACHINALE SRLInventors: Marco Bacchereti, Luca Bosio, Giorgio Soldani
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Publication number: 20220258385Abstract: A method for making a biocompatible three-dimensional object includes delivering, using a delivery system, a biocompatible fluid substance comprising a plurality of particles towards a support body having a matrix surface to obtain a coating layer of predetermined thickness configured for coating the matrix surface, generating a relative movement with at least three degrees of freedom between the support body and the delivery system, and removing from the support body any surplus particles of the biocompatible fluid substance to make uniform the predetermined thickness of the coating layer. The support body is coated with the biocompatible fluid substance to obtain a three-dimensional object having an object surface corresponding to the matrix surface.Type: ApplicationFiled: February 28, 2022Publication date: August 18, 2022Inventors: Marco Bacchereti, Luca Bosio, Giorgio Soldani
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Patent number: 11260563Abstract: An apparatus for making a biocompatible three-dimensional object including at least one delivery unit arranged to deliver at least one biocompatible fluid substance towards a support body having a matrix surface to obtain a coating layer of a predetermined thickness configured for coating the matrix surface. Furthermore, a handling unit is provided arranged to provide a relative movement according to at least 3 degrees of freedom between the support body and each delivery unit. The support body is arranged to be coated by the delivered biocompatible fluid substance, in order to obtain a three-dimensional object having an object surface copying the matrix surface of the support body.Type: GrantFiled: August 27, 2015Date of Patent: March 1, 2022Assignee: S.M. Scienzia Machinale SRLInventors: Marco Bacchereti, Luca Bosio, Giorgio Soldani
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Patent number: 10946561Abstract: A method for making a biocompatible three-dimensional heart valve includes delivering, using at least one delivery unit, a biocompatible fluid substance towards a mold having a mold surface to obtain a coating layer of predetermined thickness that coats the mold surface, where the biocompatible fluid substance includes a plurality of particles; handling the mold and the delivery unit to provide a relative movement with at least three degrees of freedom between the mold and the delivery unit, the mold coated with the biocompatible fluid substance that is delivered to obtain a three-dimensional heart valve having a surface corresponding to the mold surface; removing, using a suction and blowing device, from the mold any surplus particles of the biocompatible fluid substance dispensed to make uniform the predetermined thickness of the coating layer; and pressing a counter mold on the coating layer deposited on the mold after delivering the biocompatible fluid substance.Type: GrantFiled: May 18, 2020Date of Patent: March 16, 2021Assignee: S.M. Scienzia Machinale S.r.l.Inventors: Marco Bacchereti, Luca Bosio, Giorgio Soldani
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Publication number: 20200282607Abstract: A method for making a biocompatible three-dimensional heart valve includes delivering, using at least one delivery unit, a biocompatible fluid substance towards a mold having a mold surface to obtain a coating layer of predetermined thickness that coats the mold surface, where the biocompatible fluid substance includes a plurality of particles; handling the mold and the delivery unit to provide a relative movement with at least three degrees of freedom between the mold and the delivery unit, the mold coated with the biocompatible fluid substance that is delivered to obtain a three-dimensional heart valve having a surface corresponding to the mold surface; removing, using a suction and blowing device, from the mold any surplus particles of the biocompatible fluid substance dispensed to make uniform the predetermined thickness of the coating layer; and pressing a counter mold on the coating layer deposited on the mold after delivering the biocompatible fluid substance.Type: ApplicationFiled: May 18, 2020Publication date: September 10, 2020Inventors: Marco Bacchereti, Luca Bosio, Giorgio Soldani
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Patent number: 10654200Abstract: An apparatus for making a biocompatible three-dimensional object including at least one delivery unit arranged to deliver at least one biocompatible fluid substance towards a 3D mold having a matrix surface to obtain a coating layer of a predetermined thickness configured for coating the matrix surface. The three-dimensional object may be a heart valve. Furthermore, a handling unit is provided arranged to provide a relative movement according to at least 3 degrees of freedom between the 3D mold and each delivery unit. The 3D mold is arranged to be coated by the delivered biocompatible fluid substance, in order to obtain a three-dimensional object having an object surface copying the matrix surface of the support body.Type: GrantFiled: September 11, 2015Date of Patent: May 19, 2020Assignee: S.M. Scienzia Machinale S.R.L.Inventors: Marco Bacchereti, Luca Bosio, Giorgio Soldani
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Patent number: 10350063Abstract: A process for the manufacture of a heart valve of polymer material which provides for the deposition of a polymer solution comprising a copolymer which is preferably a copolymer of poly(carbonato-urethane) fluoridate (F-PCU) and intracatenary polydimethylsiloxane (PDMS), a PDMS with a functional group outside the chain and a solvent onto a mould using a spray technique associated with phase inversion.Type: GrantFiled: June 17, 2015Date of Patent: July 16, 2019Assignees: CONSIGLIO NAZIONALE DELLE RICERCHE, HUMANIT AS MIRASOLE S.P.A.Inventors: Giorgio Soldani, Mattia Glauber
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Publication number: 20170128200Abstract: A process for the manufacture of a heart valve of polymer material which provides for the deposition of a polymer solution comprising a copolymer which is preferably a copolymer of poly(carbonato-urethane) fluoridate (F-PCU) and intracatenary polydimethylsiloxane (PDMS), a PDMS with a functional group outside the chain and a solvent onto a mould using a spray technique associated with phase inversion.Type: ApplicationFiled: June 17, 2015Publication date: May 11, 2017Inventors: Giorgio SOLDANI, Mattia GLAUBER
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Publication number: 20160001469Abstract: An apparatus for making a biocompatible three-dimensional object including at least one delivery unit arranged to deliver at least one biocompatible fluid substance towards a 3D mold having a matrix surface to obtain a coating layer of a predetermined thickness configured for coating the matrix surface. The three-dimensional object may be a heart valve. Furthermore, a handling unit is provided arranged to provide a relative movement according to at least 3 degrees of freedom between the 3D mold and each delivery unit. The 3D mold is arranged to be coated by the delivered biocompatible fluid substance, in order to obtain a three-dimensional object having an object surface copying the matrix surface of the support body.Type: ApplicationFiled: September 11, 2015Publication date: January 7, 2016Inventors: Marco Bacchereti, Luca Bosio, Giorgio Soldani
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Publication number: 20150367542Abstract: An apparatus for making a biocompatible three-dimensional object including at least one delivery unit arranged to deliver at least one biocompatible fluid substance towards a support body having a matrix surface to obtain a coating layer of a predetermined thickness configured for coating the matrix surface. Furthermore, a handling unit is provided arranged to provide a relative movement according to at least 3 degrees of freedom between the support body and each delivery unit. The support body is arranged to be coated by the delivered biocompatible fluid substance, in order to obtain a three-dimensional object having an object surface copying the matrix surface of the support body.Type: ApplicationFiled: August 27, 2015Publication date: December 24, 2015Inventors: Marco Bacchereti, Luca Bosio, Giorgio Soldani
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Patent number: 8628787Abstract: The present invention relates to a device consisting of cross-linked nanofibrillary fibrin supported on and rooted to a microporous nonwoven fabric consisting of a biocompatible synthetic polymer material. An active ingredient is advantageously dispersed in the fibrin layer. The fibrin layer does not have a haemostatic function, but is suitable for retaining the active ingredient and releasing it with controlled kinetics. The device forming the object of the invention, preferably in the form of patches, is useful for in vitro cell cultures or for treating tissues damaged by wounds or necrosis, such as cardiac walls bearing the sequelae of infarction, or a tissue damaged by a diabetic ulcer.Type: GrantFiled: May 26, 2010Date of Patent: January 14, 2014Assignees: Consiglio Nazionale Delle Richerche, Regione ToscanaInventors: Giorgio Soldani, Enrica Briganti
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Publication number: 20120070485Abstract: The present invention relates to a device consisting of cross-linked nanofibrillary fibrin supported on and rooted to a microporous nonwoven fabric consisting of a biocompatible synthetic polymer material. An active ingredient is advantageously dispersed in the fibrin layer. The fibrin layer does not have a haemostatic function, but is suitable for retaining the active ingredient and releasing it with controlled kinetics. The device forming the object of the invention, preferably in the form of patches, is useful for in vitro cell cultures or for treating tissues damaged by wounds or necrosis, such as cardiac walls bearing the sequelae of infarction, or a tissue damaged by a diabetic ulcer.Type: ApplicationFiled: May 26, 2010Publication date: March 22, 2012Inventors: Giorgio Soldani, Enrica Briganti
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Patent number: 7157118Abstract: Process for preparing an elastomer material including a step in which a polyurethane is reacted with a polydialkylsiloxane in the presence of a solvent at a temperature below 100° C.Type: GrantFiled: October 2, 2003Date of Patent: January 2, 2007Assignee: Integrated Biomaterial & Cell Technologies S.r.l.Inventor: Giorgio Soldani
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Publication number: 20040132926Abstract: Most patients suffering from peripheral atherosclerotic vascular illnesses or from heart pathologies such as coronary ischemia need substitutive vascular ducts so as to retrieve vascular continuity, or valve substitutes so as to retrieve heart valve function.Type: ApplicationFiled: October 2, 2003Publication date: July 8, 2004Inventor: Giorgio Soldani
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Publication number: 20040123435Abstract: The machine (1) for producing porous membranes (2) for medical use comprises a plurality of reserves (25a, 25b, 25c, 26a, 26b, 26c) of components (18a, 18b, 18c, 19a, 19b, 19c) which constitute fluid substances, first and second guns (16, 17) supplied from the reserves (25a, 25b, 25c, 26a, 26b, 26c) for spraying the fluid substances onto an element (37) on which the substances are deposited and build up, the element (37) and the guns (16, 17) being mobile relative to one another for substantially even distribution of the fluid substances designed to form the membrane (2).Type: ApplicationFiled: December 12, 2003Publication date: July 1, 2004Applicant: Integrated Biomaterial & Cell Technologies S.r.I.Inventor: Giorgio Soldani
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Patent number: 5387621Abstract: Porous, distensible, gel-like membranes which in tubular form are suitable as implants, e.g., vascular prostheses and a process for the preparation thereof is described. The membranes are formed by a spraying, phase-inversion technique which employs thermodynamically unstable polymer solutions and is accomplished by separately spraying the unstable solution and a nonsolvent onto a rotating surface. Prostheses from the highly porous tubular membranes have shown a high degree of patency and completeness of the healing process and are useful for direct implantation in the body or for extracorporeal vascular accesses.Type: GrantFiled: February 11, 1993Date of Patent: February 7, 1995Assignee: Kontron Instruments, Inc.Inventor: Giorgio Soldani
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Patent number: 5229045Abstract: Porous, distensible, gel-like membranes which in tubular form are suitable as implants, e.g., vascular prostheses and a process for the preparation thereof. The membranes are formed by a spraying, phase-inversion technique which employs thermodynamically unstable polymer solutions and is accomplished by separately spraying the unstable solution and a nonsolvent onto a rotating surface. Prostheses from the highly porous tubular membranes have shown a high degree of patency and completeness of the healing process and are useful for direct implantation in the body or for extracorporeal vascular accesses.Type: GrantFiled: September 18, 1991Date of Patent: July 20, 1993Assignee: Kontron Instruments Inc.Inventor: Giorgio Soldani