Patents by Inventor Giovanni Speziali
Giovanni Speziali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230157824Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.Type: ApplicationFiled: October 31, 2022Publication date: May 25, 2023Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
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Patent number: 11534156Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.Type: GrantFiled: December 20, 2019Date of Patent: December 27, 2022Assignee: Mayo Foundation for Medical Education and ResearchInventor: Giovanni Speziali
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Patent number: 11484409Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.Type: GrantFiled: September 3, 2020Date of Patent: November 1, 2022Assignee: NeoChord, Inc.Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
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Publication number: 20210030543Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.Type: ApplicationFiled: September 3, 2020Publication date: February 4, 2021Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
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Patent number: 10765517Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.Type: GrantFiled: October 3, 2016Date of Patent: September 8, 2020Assignee: Neochord, Inc.Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
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Publication number: 20200121314Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.Type: ApplicationFiled: December 20, 2019Publication date: April 23, 2020Inventor: Giovanni Speziali
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Patent number: 10582924Abstract: A method for performing thorascopic repair of heart valves includes inserting an instrument through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a captured valve leaflet and draw a suture therethrough.Type: GrantFiled: June 27, 2017Date of Patent: March 10, 2020Assignee: Mayo Foundation for Medical Education and ResearchInventor: Giovanni Speziali
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Publication number: 20190053902Abstract: Methods and apparatus for heart valve repair utilize a heart valve repair device including a generally annular ring-like structure and a net structure. The ring-like structure is seated in the valve annulus with the net structure extending from the ring-like structure through the coaptation zone between leaflets. The net structure can then be anchored to a heart structure with a suture. Net structure extending between leaflets helps prevent prolapse of leaflets and can aid in coaptation.Type: ApplicationFiled: September 21, 2018Publication date: February 21, 2019Inventors: John Zentgraf, David Joseph Parins, Arun Saini, Giovanni Speziali
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Publication number: 20180289483Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.Type: ApplicationFiled: October 3, 2016Publication date: October 11, 2018Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
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Patent number: 10080659Abstract: Methods and apparatus for heart valve repair utilize a heart valve repair device including a generally annular ring-like structure and a net structure. The ring-like structure is seated in the valve annulus with the net structure extending from the ring-like structure through the coaptation zone between leaflets. The net structure can then be anchored to a heart structure with a suture. Net structure extending between leaflets helps prevent prolapse of leaflets and can aid in coaptation.Type: GrantFiled: December 29, 2011Date of Patent: September 25, 2018Assignee: NeoChord, Inc.Inventors: John Zentgraf, David Joseph Parins, Arun Sarini, Giovanni Speziali
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Publication number: 20170290582Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.Type: ApplicationFiled: June 27, 2017Publication date: October 12, 2017Applicant: Mayo Foundation For Medical Education and ResearchInventor: Giovanni Speziali
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Patent number: 9700300Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.Type: GrantFiled: February 5, 2015Date of Patent: July 11, 2017Assignee: Mayo Foundation For Medical Education And ResearchInventor: Giovanni Speziali
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Patent number: 9364213Abstract: A method for confirming capture of a moving heart valve leaflet of a beating heart of a patient includes inserting an instrument through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the distal end of the instrument is operable to capture a moving valve leaflet. Proper capture of the valve leaflet is confirmed at a proximal end of the instrument with a fiber optic capture confirmation system.Type: GrantFiled: May 21, 2013Date of Patent: June 14, 2016Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventor: Giovanni Speziali
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Publication number: 20150148821Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.Type: ApplicationFiled: February 5, 2015Publication date: May 28, 2015Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventor: Giovanni Speziali
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Patent number: 8968338Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a captured valve leaflet and draw the suture through the leaflet. Proper leaflet capture can be confirmed with a fiber optic imaging system.Type: GrantFiled: February 19, 2010Date of Patent: March 3, 2015Assignee: Mayo Foundation for Medical Education and ResearchInventor: Giovanni Speziali
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Publication number: 20140039324Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.Type: ApplicationFiled: May 21, 2013Publication date: February 6, 2014Inventor: Giovanni Speziali
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Patent number: 8465500Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a captured valve leaflet and draw the suture through the leaflet. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.Type: GrantFiled: January 19, 2006Date of Patent: June 18, 2013Assignee: Mayo Foundation for Medical Education and ResearchInventor: Giovanni Speziali
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Publication number: 20110224655Abstract: Intracardiac devices that can provide a plurality of functions (e.g., pacing, defibrillation, cardiac assist, or valve replacement) via a single support member and control means.Type: ApplicationFiled: September 11, 2009Publication date: September 15, 2011Inventors: Samuel J. Asirvatham, Charles J. Bruce, Paul A. Friedman, Giovanni Speziali
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Patent number: 7854762Abstract: Devices and methods that may be used to reduce valve regurgitation are disclosed by locating a body across the regurgitant valve. When the valve closes, the body obliterates/ameliorates the regurgitant orifice in the valve, thereby reducing or preventing valve regurgitation. The body may be expandable. The devices may be implantable such that they can remain in place within a subject for extended periods of time.Type: GrantFiled: May 22, 2006Date of Patent: December 21, 2010Assignee: Mayo Foundation for Medical Education and ResearchInventors: Giovanni Speziali, Charles Bruce
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Publication number: 20100174297Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.Type: ApplicationFiled: February 19, 2010Publication date: July 8, 2010Inventor: Giovanni Speziali