Patents by Inventor Giovanni Speziali

Giovanni Speziali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230157824
    Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.
    Type: Application
    Filed: October 31, 2022
    Publication date: May 25, 2023
    Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
  • Patent number: 11534156
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: December 27, 2022
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Giovanni Speziali
  • Patent number: 11484409
    Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: November 1, 2022
    Assignee: NeoChord, Inc.
    Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
  • Publication number: 20210030543
    Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.
    Type: Application
    Filed: September 3, 2020
    Publication date: February 4, 2021
    Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
  • Patent number: 10765517
    Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: September 8, 2020
    Assignee: Neochord, Inc.
    Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
  • Publication number: 20200121314
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.
    Type: Application
    Filed: December 20, 2019
    Publication date: April 23, 2020
    Inventor: Giovanni Speziali
  • Patent number: 10582924
    Abstract: A method for performing thorascopic repair of heart valves includes inserting an instrument through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a captured valve leaflet and draw a suture therethrough.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: March 10, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Giovanni Speziali
  • Publication number: 20190053902
    Abstract: Methods and apparatus for heart valve repair utilize a heart valve repair device including a generally annular ring-like structure and a net structure. The ring-like structure is seated in the valve annulus with the net structure extending from the ring-like structure through the coaptation zone between leaflets. The net structure can then be anchored to a heart structure with a suture. Net structure extending between leaflets helps prevent prolapse of leaflets and can aid in coaptation.
    Type: Application
    Filed: September 21, 2018
    Publication date: February 21, 2019
    Inventors: John Zentgraf, David Joseph Parins, Arun Saini, Giovanni Speziali
  • Publication number: 20180289483
    Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.
    Type: Application
    Filed: October 3, 2016
    Publication date: October 11, 2018
    Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
  • Patent number: 10080659
    Abstract: Methods and apparatus for heart valve repair utilize a heart valve repair device including a generally annular ring-like structure and a net structure. The ring-like structure is seated in the valve annulus with the net structure extending from the ring-like structure through the coaptation zone between leaflets. The net structure can then be anchored to a heart structure with a suture. Net structure extending between leaflets helps prevent prolapse of leaflets and can aid in coaptation.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: September 25, 2018
    Assignee: NeoChord, Inc.
    Inventors: John Zentgraf, David Joseph Parins, Arun Sarini, Giovanni Speziali
  • Publication number: 20170290582
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.
    Type: Application
    Filed: June 27, 2017
    Publication date: October 12, 2017
    Applicant: Mayo Foundation For Medical Education and Research
    Inventor: Giovanni Speziali
  • Patent number: 9700300
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: July 11, 2017
    Assignee: Mayo Foundation For Medical Education And Research
    Inventor: Giovanni Speziali
  • Patent number: 9364213
    Abstract: A method for confirming capture of a moving heart valve leaflet of a beating heart of a patient includes inserting an instrument through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the distal end of the instrument is operable to capture a moving valve leaflet. Proper capture of the valve leaflet is confirmed at a proximal end of the instrument with a fiber optic capture confirmation system.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: June 14, 2016
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventor: Giovanni Speziali
  • Publication number: 20150148821
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.
    Type: Application
    Filed: February 5, 2015
    Publication date: May 28, 2015
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventor: Giovanni Speziali
  • Patent number: 8968338
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a captured valve leaflet and draw the suture through the leaflet. Proper leaflet capture can be confirmed with a fiber optic imaging system.
    Type: Grant
    Filed: February 19, 2010
    Date of Patent: March 3, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Giovanni Speziali
  • Publication number: 20140039324
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.
    Type: Application
    Filed: May 21, 2013
    Publication date: February 6, 2014
    Inventor: Giovanni Speziali
  • Patent number: 8465500
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a captured valve leaflet and draw the suture through the leaflet. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.
    Type: Grant
    Filed: January 19, 2006
    Date of Patent: June 18, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Giovanni Speziali
  • Publication number: 20110224655
    Abstract: Intracardiac devices that can provide a plurality of functions (e.g., pacing, defibrillation, cardiac assist, or valve replacement) via a single support member and control means.
    Type: Application
    Filed: September 11, 2009
    Publication date: September 15, 2011
    Inventors: Samuel J. Asirvatham, Charles J. Bruce, Paul A. Friedman, Giovanni Speziali
  • Patent number: 7854762
    Abstract: Devices and methods that may be used to reduce valve regurgitation are disclosed by locating a body across the regurgitant valve. When the valve closes, the body obliterates/ameliorates the regurgitant orifice in the valve, thereby reducing or preventing valve regurgitation. The body may be expandable. The devices may be implantable such that they can remain in place within a subject for extended periods of time.
    Type: Grant
    Filed: May 22, 2006
    Date of Patent: December 21, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Giovanni Speziali, Charles Bruce
  • Publication number: 20100174297
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.
    Type: Application
    Filed: February 19, 2010
    Publication date: July 8, 2010
    Inventor: Giovanni Speziali