Patents by Inventor Gisela Claassen

Gisela Claassen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-Aryl-6-aryl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and analogs as activators of caspases and inducers of apoptosis and the use thereof
    Publication number: 20080045514
    Abstract: Disclosed are 3-aryl-6-aryl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and analogs thereof, represented by the Formula I: wherein Ar1, Q2, R1, R2, dashed line and X are defined herein. The present invention relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
    Type: Application
    Filed: July 18, 2007
    Publication date: February 21, 2008
    Applicant: Cytovia, Inc.
    Inventors: Sui Cai, John Drewe, Han-Zhong Zhang, Shailaja Kasibhatla, Gisela Claassen, Nilantha Sirisoma, William Kemnitzer
  • Novel assays for assessing cancerous cell growth
    Publication number: 20060234249
    Abstract: The present invention provides novel assays for assessing cancerous cell growth. The invention is useful for the identification and validation of oncogenes and tumor suppressors, as well as for the identification and validation of therapeutic compounds for the treatment of cancer.
    Type: Application
    Filed: April 15, 2005
    Publication date: October 19, 2006
    Applicant: Immusol Incorporated
    Inventors: Ning Ke, De-Hua Yu, Aaron Albers, Gisela Claassen, Henry (Qi-Xiang) Li, Flossie Wong-Staal
  • GPR 39 modulators that control cancerous cell growth
    Publication number: 20040071708
    Abstract: The present invention discloses compositions, systems and methods for identifying anti-cancer agents using doth in vitro and in vivo techniques. Embodiments include the screening of combinatorial libraries of peptides, antibodies, and small organic molecules as well as siRNAs, ribozymes and antisense nucleotides directed against nucleic acids encoding the GPR 39 protein.
    Type: Application
    Filed: September 26, 2002
    Publication date: April 15, 2004
    Applicant: Immusol, Inc.
    Inventors: Gisela Claassen, Henry Li, Jack Barber