Patents by Inventor Gisela Weskamp

Gisela Weskamp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATMENT USING PROTEIN BINDERS TO IRHOM2 EPITOPES
    Publication number: 20240174744
    Abstract: The present disclosure relates to a method for inhibiting or reducing TACE/ADAM17 activity in a human or animal subject. The method comprises administering to the human or animal subject an effective amount for reducing or inhibiting TACE/ADAM 17 activity of a protein binder which, when bound to human iRhom2, binds at least within a region of Loop 1 thereof, or of a nucleic acid that encodes for at least one chain of a protein binder which, when bound to human iRhom2, binds at least within a region of Loop 1 thereof.
    Type: Application
    Filed: March 29, 2022
    Publication date: May 30, 2024
    Inventors: Matthias SCHNEIDER, Kerstin SELLE, Jens RUHE, Gisela WESKAMP, Carl BLOBEL
  • HUMANIZED ANTIBODIES AGAINST IRHOM2
    Publication number: 20240166767
    Abstract: The present invention relates to humanized antibodies or target-binding fragments or derivatives thereof retaining target binding capacities, which bind to human iRhom2.
    Type: Application
    Filed: February 25, 2022
    Publication date: May 23, 2024
    Inventors: Matthias SCHNEIDER, Jens RUHE, Gisela WESKAMP, Carl BLOBEL
  • PROTEIN BINDERS FOR IRHOM2
    Publication number: 20220204610
    Abstract: The present invention relates to a protein binder that binds to human iRhom2, and inhibits and/or reduces TACE/ADAM17 activity when bound to human iRhom2.
    Type: Application
    Filed: April 9, 2020
    Publication date: June 30, 2022
    Inventors: Matthias Schneider, Kerstin Selle, Jens Ruhe, Gisela Weskamp, Carl Blobel
  • Antibodies that mimic actions of neurotrophins
    Patent number: 7459156
    Abstract: The use and production of immunoglobulins which activate trk receptors and imitate effects of neurotrophins are provided. Immunoglobulins which block trk receptor activation and methods of use are also provided.
    Type: Grant
    Filed: August 25, 2003
    Date of Patent: December 2, 2008
    Assignee: The Regents of the University of California
    Inventors: Douglas O. Clary, Gisela Weskamp, LeeAnn R. Austin, Louis F. Reichardt
  • Antibodies that mimic actions of neurotrophins
    Publication number: 20040109860
    Abstract: The use and production of immunoglobulins which activate trk receptors and imitate effects of neurotrophins are provided. Immunoglobulins which block trk receptor activation and methods of use are also provided.
    Type: Application
    Filed: January 23, 2004
    Publication date: June 10, 2004
    Inventors: Douglas O. Clary, Gisela Weskamp, LeeAnn R. Austin, Louis F. Reichardt
  • Antibodies that mimic actions of neurotrophins
    Patent number: 6656465
    Abstract: The use and production of immunoglobulins which activate trk receptors and imitate effects of neurotrophins are provided. Immunoglobulins which block trk receptor activation and methods of use are also provided.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: December 2, 2003
    Assignee: The Regents of the University of California
    Inventors: Douglas O. Clary, Gisela Weskamp, Leeann R. Austin, Louis F. Reichardt
  • Antibodies that mimic actions of neurotrophins
    Publication number: 20020054874
    Abstract: The use and production of immunoglobulins which activate trk receptors and imitate effects of neurotrophins are provided. Immunoglobulins which block trk receptor activation and methods of use are also provided.
    Type: Application
    Filed: January 26, 2001
    Publication date: May 9, 2002
    Applicant: The Regents of the University of California
    Inventors: Douglas O. Clary, Gisela Weskamp, Leeann R. Austin, Louis F. Reichardt
  • Antibodies that mimic actions of neurotrophins
    Patent number: 5753225
    Abstract: The use and production of immunoglobulins which activate trk receptors and imitate effects of neurotrophins are provided. Immunoglobulins which block trk receptor activation and methods of use are also provided.
    Type: Grant
    Filed: December 3, 1993
    Date of Patent: May 19, 1998
    Assignee: The Regents of the University of California
    Inventors: Douglas O. Clary, Gisela Weskamp, Leeann R. Austin, Louis F. Reichardt