Abstract: A method and system for frequency matching a resonant cavity is disclosed. Light is received in a resonant cavity having at least a first mirror and a second mirror defining a path along which light is reflected. At least the second mirror is actuatable to vary the length of the path of the resonant cavity. An intensity of the light exiting or reflecting from the resonant cavity is monitored, and an error correction is determined. The second mirror is actuated towards a pose relative to the first mirror at which a frequency of the light is in resonance with the length of the path. In this manner, the resonant cavity is frequency matched to the light to maintain the resonant cavity in resonance.

Abstract: Methods and systems for analyzing a sample and generating a predictive model using cavity ring-down spectroscopy are disclosed. At least part of a sample is loaded in a ring-down cavity. For each of a set of wavelengths, a laser beam is generated and directed into the ring-down cavity. The laser beam entering the ring-down cavity is extinguished. Light intensity decay data for light exiting the ring-down cavity is registered via a light intensity sensor system. A probability is determined from the light intensity decay data for the set of wavelengths that a subject from which the sample was received has a physiological condition or a degree of the physiological condition at least indirectly using a dataset of light intensity decay data for previously analyzed samples for which the presence or the absence of the physiological condition or the degree of the physiological condition have been identified.

Abstract: A method and system for frequency matching a resonant cavity is disclosed. Light is received in a resonant cavity having at least a first mirror and a second mirror defining a path along which light is reflected. At least the second mirror is actuatable to vary the length of the path of the resonant cavity. An intensity of the light exiting or reflecting from the resonant cavity is monitored, and an error correction is determined. The second mirror is actuated towards a pose relative to the first mirror at which a frequency of the light is in resonance with the length of the path. In this manner, the resonant cavity is frequency matched to the light to maintain the resonant cavity in resonance.

Abstract: Methods and systems for analyzing a sample and generating a predictive model using cavity ring-down spectroscopy are disclosed. At least part of a sample is loaded in a ring-down cavity. For each of a set of wavelengths, a laser beam is generated and directed into the ring-down cavity. The laser beam entering the ring-down cavity is extinguished. Light intensity decay data for light exiting the ring-down cavity is registered via a light intensity sensor system. A probability is determined from the light intensity decay data for the set of wavelengths that a subject from which the sample was received has a physiological condition or a degree of the physiological condition at least indirectly using a dataset of light intensity decay data for previously analyzed samples for which the presence or the absence of the physiological condition or the degree of the physiological condition have been identified.

Abstract: A system for producing single-frequency or near-single-frequency operation of a laser beam includes a laser for emitting a laser beam at each one of a plurality of cavity lengths, A detector is configured to receive at least a portion of the laser beam emitted, and generate a signal. A computer system is configured to identify at least one beat note in the signal for each of at least one of the plurality of cavity lengths, the at least one beat note indicating the presence of one or more higher-order transverse modes, longitudinal modes, or both, in the received at least the portion of the laser beam emitted at the at least one of the plurality of cavity lengths. The cavity is adjusted to one of the plurality of cavity lengths for eliminating or minimizing the at least one beat note.

Abstract: Methods and systems for analyzing a sample and generating a predictive model using cavity ring-down spectroscopy are disclosed. At least part of a sample is loaded in a ring-down cavity. For each of a set of wavelengths, a laser beam is generated and directed into the ring-down cavity. The laser beam entering the ring-down cavity is extinguished. Light intensity decay data for light exiting the ring-down cavity is registered via a light intensity sensor system. A probability is determined from the light intensity decay data for the set of wavelengths that a subject from which the sample was received has a physiological condition or a degree of the physiological condition at least indirectly using a dataset of light intensity decay data for previously analyzed samples for which the presence or the absence of the physiological condition or the degree of the physiological condition have been identified.

Abstract: A system for producing single-frequency or near-single-frequency operation of a laser beam includes a laser for emitting a laser beam at each one of a plurality of cavity lengths, A detector is configured to receive at least a portion of the laser beam emitted, and generate a signal. A computer system is configured to identify at least one beat note in the signal for each of at least one of the plurality of cavity lengths, the at least one beat note indicating the presence of one or more higher-order transverse modes, longitudinal modes, or both, in the received at least the portion of the laser beam emitted at the at least one of the plurality of cavity lengths. The cavity is adjusted to one of the plurality of cavity lengths for eliminating or minimizing the at least one beat note.

Abstract: Methods and systems for analyzing a sample and generating a predictive model using cavity ring-down spectroscopy are disclosed. At least part of a sample is loaded in a ring-down cavity. For each of a set of wavelengths, a laser beam is generated and directed into the ring-down cavity. The laser beam entering the ring-down cavity is extinguished. Light intensity decay data for light exiting the ring-down cavity is registered via a light intensity sensor system. A probability is determined from the light intensity decay data for the set of wavelengths that a subject from which the sample was received has a physiological condition or a degree of the physiological condition at least indirectly using a dataset of light intensity decay data for previously analyzed samples for which the presence or the absence of the physiological condition or the degree of the physiological condition have been identified.

Abstract: A system for producing single-frequency or near-single-frequency operation of a laser beam includes a laser for emitting a laser beam at each one of a plurality of cavity lengths, A detector is configured to receive at least a portion of the laser beam emitted, and generate a signal. A computer system is configured to identify at least one beat note in the signal for each of at least one of the plurality of cavity lengths, the at least one beat note indicating the presence of one or more higher-order transverse modes, longitudinal modes, or both, in the received at least the portion of the laser beam emitted at the at least one of the plurality of cavity lengths. The cavity is adjusted to one of the plurality of cavity lengths for eliminating or minimizing the at least one beat note.

Abstract: A method and system for obtaining single-frequency operation of a laser system. A laser beam is emitted from a laser cavity, having an adjustable length, at a plurality of cavity lengths. At least a portion of the laser beam is received at a detector, which detects the presence of transverse and/or longitudinal modes in the laser beam, and generates a laser beam signal having a beat-note indicative thereof. The laser beam signal for each of the plurality of cavity lengths can be analyzed, and a cavity length of best mode purity, indicating single-frequency operation, can be selected. The laser beam system can emit a laser and have a laser beam splitter for directing at least a portion of the emitted laser beam to a laser beam detector for generating at least one laser beam signal therefrom, and an actuator for adjusting the length of the laser cavity.

Abstract: A method and system for obtaining single-frequency operation of a laser system. A laser beam is emitted from a laser cavity, having an adjustable length, at a plurality of cavity lengths. At least a portion of the laser beam is received at a detector, which detects the presence of transverse and/or longitudinal modes in the laser beam, and generates a laser beam signal having a beat-note indicative thereof. The laser beam signal for each of the plurality of cavity lengths can be analyzed, and a cavity length of best mode purity, indicating single-frequency operation, can be selected. The laser beam system can emit a laser and have a laser beam splitter for directing at least a portion of the emitted laser beam to a laser beam detector for generating at least one laser beam signal therefrom, and an actuator for adjusting the length of the laser cavity.