Patents by Inventor Giulio Volpe

Giulio Volpe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of pure citalopram
    Patent number: 6855834
    Abstract: A process for the preparation of citalopram of formula (I) in which a compound of formula (II) wherein Z is iodo, bromo, chloro or CF3—(CF2)n—SO2—O— n being 0, 1, 2, 3, 4, 5, 6, 7 or 8, is subjected to a cyanide exchange reaction in which the group Z is exchanged with cyanide by reaction with a cyanide source; the resultant crude citalopram product is optionally subjected to some initial purification and the crude citalopram base is subsequently subjected to a film distillation process; the resulting citalopram product is then optionally further purified and worked up and isolated as the base or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: February 15, 2005
    Assignee: H. Lundbeck A/S
    Inventors: Andrea Castellin, Giulio Volpe, Federico Sbrogiò
  • Process for the preparation of pure citalopram
    Publication number: 20030178295
    Abstract: A process for the preparation of citalopram of formula (I) 1
    Type: Application
    Filed: February 10, 2003
    Publication date: September 25, 2003
    Applicant: H. LUNDBECK A/S
    Inventors: Andrea Castellin, Giulio Volpe, Federico Sbrogio
  • Process for the preparation of pure citalopram
    Publication number: 20020087012
    Abstract: A process for the preparation of citalopram of formula (I) 1
    Type: Application
    Filed: December 20, 2001
    Publication date: July 4, 2002
    Applicant: H. Lundbeck A/S
    Inventors: Andrea Castellin, Giulio Volpe, Federico Sbrogio