Patents by Inventor Giuseppe Barbanti-Brodano

Giuseppe Barbanti-Brodano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid viral plasmid and microorganisms containing same
    Patent number: 4562155
    Abstract: pML BK is a hybrid plasmid which is constructed of :pML which contains the entire nucleotide sequence of the plasmid pBR322 except for deletion of nucleotide sequences 1120-2490 bp and 0 to 375 bp, and BK which contains the entire nucleotide sequence of the Gardner strain of BK virus except for deletion of nucleotide sequences between bp 5089-5196. Into the pML BK plasmid may be inserted a viral or human gene X to be expressed, an example of which is TK which represents the Bam HI generated 3,600 bp DNA fragment of herpes simplex virus type 1 which contains the herpes simplex virus type 1 TK DNA. The majority of the pML BK X DNA molecules remain in the episomal or free state in the human cells 143B and express the gene X.
    Type: Grant
    Filed: May 19, 1983
    Date of Patent: December 31, 1985
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: Robert P. Ricciardi, Giuseppe Barbanti-Brodano, Gabriele Milanesi