Patents by Inventor Giuseppe Ciaramella

Giuseppe Ciaramella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ZIKA VIRUS RNA VACCINES
    Publication number: 20190008946
    Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 10, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks
  • NUCLEIC ACID VACCINES
    Publication number: 20190000959
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
    Type: Application
    Filed: July 27, 2018
    Publication date: January 3, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Axel Bouchon, Eric Yi-Chun Huang
  • CHIKV RNA VACCINES
    Publication number: 20180344839
    Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
    Type: Application
    Filed: June 15, 2018
    Publication date: December 6, 2018
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Kapil Bahl, Tal Zaks, Sunny Himansu, Sayda Mahgoub Elbashir
  • DENV RNA VACCINES
    Publication number: 20180344838
    Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
    Type: Application
    Filed: June 15, 2018
    Publication date: December 6, 2018
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Kapil Bahl, Tal Zaks, Sunny Himansu
  • COMBINATION PIV3/HMPV RNA VACCINES
    Publication number: 20180326045
    Abstract: The disclosure relates to respiratory virus ribonucleic acid (RNA) vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: July 20, 2018
    Publication date: November 15, 2018
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu
  • Zika virus RNA vaccines
    Patent number: 10124055
    Abstract: The disclosure relates to Zika virus infection and the treatment thereof. The invention includes ribonucleic acid compositions, as well as methods of using the compositions for treating and preventing Zika virus infection.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: November 13, 2018
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks
  • CANCER VACCINES
    Publication number: 20180318409
    Abstract: The disclosure relates to cancer ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: October 21, 2016
    Publication date: November 8, 2018
    Applicant: ModernaTX, Inc.
    Inventors: Nicholas Valiante, Tal Zaks, Eric Yi-Chun Huang, Giuseppe Ciaramella
  • BROAD SPECTRUM INFLUENZA VIRUS VACCINE
    Publication number: 20180311336
    Abstract: The disclosure relates to influenza virus ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: October 21, 2016
    Publication date: November 1, 2018
    Applicant: Moderna TX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Kerim Babaoglu, Jessica Ann Flynn, Lan Zhang
  • HIGH POTENCY IMMUNOGENIC COMPOSITIONS
    Publication number: 20180312549
    Abstract: Provided herein, in some embodiments, are immunogenic compositions that include a cationic lipid nanoparticle (LNP) encapsulating messenger ribonucleic acid (mRNA) having an open reading frame encoding a viral, bacterial or parasitic antigen, a pan HLA DR-binding epitope (PADRE), and a 5? terminal cap modified to increase mRNA translation efficiency.
    Type: Application
    Filed: July 10, 2018
    Publication date: November 1, 2018
    Applicant: ModernaTX, Inc.
    Inventor: Giuseppe Ciaramella
  • HERPES SIMPLEX VIRUS VACCINE
    Publication number: 20180303929
    Abstract: The disclosure relates to herpes simplex virus (HSV) ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: October 21, 2016
    Publication date: October 25, 2018
    Applicant: Moderna TX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Andrew J. Bett, Danilo R. Casimiro
  • SEXUALLY TRANSMITTED DISEASE VACCINES
    Publication number: 20180296662
    Abstract: The disclosure relates to sexually transmitted disease ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: June 29, 2018
    Publication date: October 18, 2018
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu
  • SEXUALLY TRANSMITTED DISEASE VACCINES
    Publication number: 20180289792
    Abstract: The disclosure relates to sexually transmitted disease ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: October 21, 2016
    Publication date: October 11, 2018
    Applicant: ModernaTX. Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu
  • ZIKA RNA VACCINES
    Publication number: 20180280496
    Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
    Type: Application
    Filed: June 15, 2018
    Publication date: October 4, 2018
    Applicant: ModernaTX, Inc.
    Inventors: GIUSEPPE CIARAMELLA, ERIC YI-CHUN HUANG, KAPIL BAHL, TAL ZAKS, SUNNY HIMANSU
  • HUMAN CYTOMEGALOVIRUS RNA VACCINES
    Publication number: 20180271975
    Abstract: The disclosure describes HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: June 12, 2018
    Publication date: September 27, 2018
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi
  • RESPIRATORY SYNCYTIAL VIRUS VACCINE
    Publication number: 20180271970
    Abstract: The disclosure relates to respiratory syncytial virus (RSV) ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: October 21, 2016
    Publication date: September 27, 2018
    Applicant: ModernaTX, INC.
    Inventors: Giuseppe Ciaramella, Kapil Bahl, Amy Espeseth, Dai Wang, Andrew J. Bett
  • Human cytomegalovirus RNA vaccines
    Patent number: 10064935
    Abstract: The disclosure describes HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: September 4, 2018
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi
  • Combination PIV3/hMPV RNA vaccines
    Patent number: 10064934
    Abstract: The disclosure relates to respiratory virus ribonucleic acid (RNA) vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: September 4, 2018
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu
  • EBOLA/MARBURG VACCINES
    Publication number: 20180243225
    Abstract: The disclosure relates to Ebola virus and/or Marburg virus ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding Ebola virus and/or Marburg virus. Methods for preparing and using such vaccines are also described.
    Type: Application
    Filed: January 25, 2018
    Publication date: August 30, 2018
    Applicant: ModernaTX, Inc.
    Inventor: Giuseppe Ciaramella
  • Nucleic acid vaccines
    Patent number: 10022435
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: July 17, 2018
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Axel Bouchon, Eric Yi-Chun Huang
  • HUMAN CYTOMEGALOVIRUS RNA VACCINES
    Publication number: 20180028645
    Abstract: The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: August 11, 2017
    Publication date: February 1, 2018
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi