Patents by Inventor Giuseppe Orlando

Giuseppe Orlando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ORGAN/TISSUE DECELLULARIZATION, FRAMEWORK MAINTENANCE AND RECELLULARIZATION
    Publication number: 20230310708
    Abstract: Methods for decellularizing organs and tissues in vitro and in vivo are provided, as are methods of maintaining organ and tissue frameworks and methods of recellularizing organs and tissues, thereby providing an approach to needed organs or tissues.
    Type: Application
    Filed: February 17, 2023
    Publication date: October 5, 2023
    Inventors: Giuseppe Orlando, Shay Soker
  • Organ/tissue decellularization, framework maintenance and recellularization
    Patent number: 11648335
    Abstract: Methods for decellularizing organs and tissues in vitro and in vivo are provided, as are methods of maintaining organ and tissue frameworks and methods of recellularizing organs and tissues, thereby providing an approach to needed organs or tissues.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: May 16, 2023
    Assignee: WAKE FOREST UNIVERSITY HEALTH SCIENCES
    Inventors: Giuseppe Orlando, Shay Soker
  • MINIMAL PROCESSING METHOD FOR DECELLULARIZATION OF TISSUES
    Publication number: 20220305175
    Abstract: Provided herein are improved methods of decellularizing pancreas and other tissues. The methods according to some embodiments are water-based and may be detergent-free, allowing for the production of acellular scaffolds whereby the matrisome is better preserved. Compositions comprising decellularized tissue and methods of use thereof are also provided.
    Type: Application
    Filed: May 8, 2020
    Publication date: September 29, 2022
    Inventors: Giuseppe Orlando, Riccardo Tamburrini
  • CAPSULE COMPRISING INSULIN-SECRETING CELLS FOR TREATING DIABETES
    Publication number: 20220168232
    Abstract: A capsule including alginate encapsulating: insulin-secreting cells, a RGD-alginate, mesenchymal stem cells, extracellular matrix, the process for the preparation thereof and the use thereof for treating diabetes.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 2, 2022
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, ETABLISSEMENT FRANCAIS DU SANG, WAKE FOREST UNIVERSITY HEALTH SCIENCES
    Inventors: Sandrine LABLANCHE, Pierre-Yves BENHAMOU, Emily TUBBS, Anaïck MOISAN, Harald EGELHOFER, Virginie PERSOONS, Florence RIVERA, Frédéric BOTTAUSCI, Maxime PIERRON, Giuseppe ORLANDO, Riccardo TAMBURRINI
  • ORGAN/TISSUE DECELLULARIZATION, FRAMEWORK MAINTENANCE AND RECELLULARIZATION
    Publication number: 20150238656
    Abstract: Methods for decellularizing organs and tissues in vitro and in vivo are provided, as are methods of maintaining organ and tissue frameworks and methods of recellularizing organs and tissues, thereby providing an approach to needed organs or tissues.
    Type: Application
    Filed: January 30, 2015
    Publication date: August 27, 2015
    Inventors: Giuseppe Orlando, Shay Soker