Patents by Inventor Glen A. Scoles

Glen A. Scoles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vitro parasite feeding system
    Patent number: 10888071
    Abstract: The system includes a feeding vessel having an inlet, an outlet, and a membrane positioned across an opening in the vessel. Parasites (preferably ticks) are allowed to attach themselves to the membrane so that as a feeding fluid (preferably blood) is circulated through the vessel, the parasites feed on the feeding fluid through the membrane.
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: January 12, 2021
    Assignee: The United States of America, as Represented by The Secretary of Agriculture
    Inventors: Massaro W. Ueti, Glen A. Scoles, Donald P. Knowles, Jr.
  • Aquaporin 2 protects cattle from ticks and tick-borne parasites
    Patent number: 10722561
    Abstract: A novel method of using an aquaporin protein from Rhipicephalus microplus (RmAQP2), fragments of RmAQP2, and/or the cDNA encoding RmAQP2 and/or the fragments are described. Immunogenic composition containing recombinant RmAQP2 and/or fragments of RmAQP2 are produced and administered to an ungulate which generates an immune response to RmAQP2. After feeding female ticks on the ungulate injected with RmAQP2 and/or fragments of RmAQP2, the female ticks have lower reproductive viability because of a reduced egg mass, reduced hatching percentage, and reduced survival of larvae. Thus, administering RmAQP2 and/or RmAQP2 fragments to an ungulate can reduce the incidence of R. microplus and also reduce the incidence of tick-borne pathogens in ungulates because of the lower number of R. microplus.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: July 28, 2020
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Glen A. Scoles, Felicito Guerrero, Reginaldo Bastos
  • AQUAPORIN 2 PROTECTS CATTLE FROM TICKS AND TICK-BORNE PARASITES
    Publication number: 20180311327
    Abstract: A novel method of using an aquaporin protein from Rhipicephalus microplus (RmAQP2), fragments of RmAQP2, and/or the cDNA encoding RmAQP2 and/or the fragments are described. Immunogenic composition containing recombinant RmAQP2 and/or fragments of RmAQP2 are produced and administered to an ungulate which generates an immune response to RmAQP2. After feeding female ticks on the ungulate injected with RmAQP2 and/or fragments of RmAQP2, the female ticks have lower reproductive viability because of a reduced egg mass, reduced hatching percentage, and reduced survival of larvae. Thus, administering RmAQP2 and/or RmAQP2 fragments to an ungulate can reduce the incidence of R. microplus and also reduce the incidence of tick-borne pathogens in ungulates because of the lower number of R. microplus.
    Type: Application
    Filed: July 12, 2018
    Publication date: November 1, 2018
    Inventors: Glen A. Scoles, Felicito Guerrero, Reginaldo Bastos
  • Aquaporin 2 protects cattle from ticks and tick-borne parasites
    Patent number: 10052369
    Abstract: A novel method of using an aquaporin protein from Rhipicephalus microplus (RmAQP2), fragments of RmAQP2, and/or the cDNA encoding RmAQP2 and/or the fragments are described. Immunogenic composition containing recombinant RmAQP2 and/or fragments of RmAQP2 are produced and administered to an ungulate which generates an immune response to RmAQP2. After feeding female ticks on the ungulate injected with RmAQP2 and/or fragments of RmAQP2, the female ticks have lower reproductive viability because of a reduced egg mass, reduced hatching percentage, and reduced survival of larvae. Thus, administering RmAQP2 and/or RmAQP2 fragments to an ungulate can reduce the incidence of R. microplus and also reduce the incidence of tick-borne pathogens in ungulates because of the lower number of R. microplus.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: August 21, 2018
    Assignees: The United States of America, as represented by the Secretary of Agriculture, Washington State University
    Inventors: Glen A. Scoles, Felicito Guerrero, Reginaldo Bastos
  • IN VITRO PARASITE FEEDING SYSTEM
    Publication number: 20170238513
    Abstract: The system includes a feeding vessel having an inlet, an outlet, and a membrane positioned across an opening in the vessel. Parasites (preferably ticks) are allowed to attach themselves to the membrane so that as a feeding fluid (preferably blood) is circulated through the vessel, the parasites feed on the feeding fluid through the membrane.
    Type: Application
    Filed: February 23, 2016
    Publication date: August 24, 2017
    Inventors: Massaro W. Ueti, Glen A. Scoles, Donald P. Knowles, JR.
  • AQUAPORIN 2 PROTECTS CATTLE FROM TICKS AND TICK-BORNE PARASITES
    Publication number: 20160361396
    Abstract: A novel method of using an aquaporin protein from Rhipicephalus microplus (RmAQP2), fragments of RmAQP2, and/or the cDNA encoding RmAQP2 and/or the fragments are described. Immunogenic composition containing recombinant RmAQP2 and/or fragments of RmAQP2 are produced and administered to an ungulate which generates an immune response to RmAQP2. After feeding female ticks on the ungulate injected with RmAQP2 and/or fragments of RmAQP2, the female ticks have lower reproductive viability because of a reduced egg mass, reduced hatching percentage, and reduced survival of larvae. Thus, administering RmAQP2 and/or RmAQP2 fragments to an ungulate can reduce the incidence of R. microplus and also reduce the incidence of tick-borne pathogens in ungulates because of the lower number of R. microplus.
    Type: Application
    Filed: June 9, 2016
    Publication date: December 15, 2016
    Inventors: Glen A. Scoles, Felicito Guerrero, Reginaldo Bastos