Patents by Inventor Glen E. Southard

Glen E. Southard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11458453
    Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: October 4, 2022
    Assignee: 6TH Wave Innovations Corp.
    Inventors: Jonathan P. Gluckman, Glen E. Southard
  • Patent number: 11389782
    Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: July 19, 2022
    Assignee: 6th Wave Innovations Corp.
    Inventors: Jonathan P. Gluckman, Glen E. Southard
  • Publication number: 20210252477
    Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.
    Type: Application
    Filed: September 23, 2020
    Publication date: August 19, 2021
    Inventors: Jonathan P. Gluckman, Glen E. Southard
  • Patent number: 10814306
    Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: October 27, 2020
    Assignee: 6th Wave Innovations Corp.
    Inventors: Jonathan P. Gluckman, Glen E. Southard
  • Publication number: 20180214845
    Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.
    Type: Application
    Filed: June 8, 2016
    Publication date: August 2, 2018
    Inventors: Jonathan P. Gluckman, Glen E. Southard
  • Publication number: 20180117564
    Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.
    Type: Application
    Filed: November 3, 2017
    Publication date: May 3, 2018
    Inventors: Jonathan P. Gluckman, Glen E. Southard
  • Patent number: 9504988
    Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: November 29, 2016
    Assignee: 6th Wave Innovations Corp.
    Inventors: Jonathan P. Gluckman, Glen E. Southard
  • Patent number: 9211107
    Abstract: A ruggedized hydrogel product that is formulated to withstand the effects of high-energy sterilization procedures, such as gamma beam and electron beam sterilization, without significant structural degradation is disclosed. This enables the hydrogel product to be suitable for use in medical applications where sterile components are required. In one embodiment a ruggedized hydrogel product is disclosed and comprises a gel component, water for hydrating the gel component, and at least one free radical absorber component that is capable of absorbing free radicals produced when the hydrogel product is sterilized via a high-energy sterilization procedure. The free radical absorber component in one embodiment includes potassium metabisulfite and ascorbic acid. The ruggedized hydrogel product can be included with an ultrasound probe to provide an acoustically transparent interface between the probe and the skin of a patient.
    Type: Grant
    Filed: November 7, 2012
    Date of Patent: December 15, 2015
    Assignee: C. R. Bard, Inc.
    Inventors: Jeremy B. Cox, Glen E. Southard, Shayne Messerly
  • Patent number: 8591842
    Abstract: A molecularly imprinted polymer ion exchange resin for selectively removing one or more inorganic ions in a liquid medium is disclosed and described. The exchange resin can include a bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in a liquid medium. A process for preparing a molecularly imprinted polymer ion exchange resin can include (a) polymerizing a polmerizable mixture in the presence of an inorganic ion imprinting complex to form a bead, said inorganic ion imprinting complex including a ligand and an inorganic ion; and (b) removing the inorganic ions from the bead to form the molecularly imprinted polymer ion exchange resin, the bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in an liquid medium.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: November 26, 2013
    Assignee: The Johns Hopkins University
    Inventors: George M. Murray, Kelly A. Van Houten, Glen E. Southard
  • Publication number: 20120012530
    Abstract: A molecularly imprinted polymer ion exchange resin for selectively removing one or more inorganic ions in a liquid medium is disclosed and described. The exchange resin can include a bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in a liquid medium. A process for preparing a molecularly imprinted polymer ion exchange resin can include (a) polymerizing a polmerizable mixture in the presence of an inorganic ion imprinting complex to form a bead, said inorganic ion imprinting complex including a ligand and an inorganic ion; and (b) removing the inorganic ions from the bead to form the molecularly imprinted polymer ion exchange resin, the bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in an liquid medium.
    Type: Application
    Filed: September 27, 2011
    Publication date: January 19, 2012
    Applicant: JOHNS HOPKINS UNIVERSITY
    Inventors: George M. Murray, Kelly A. Van Houten, Glen E. Southard
  • Patent number: 8058208
    Abstract: A molecularly imprinted polymer ion exchange resin for selectively removing one or more inorganic ions in a liquid medium is disclosed and described. The exchange resin can include a bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in a liquid medium. A process for preparing a molecularly imprinted polymer ion exchange resin can include (a) polymerizing a polmerizable mixture in the presence of an inorganic ion imprinting complex to form a bead, said inorganic ion imprinting complex including a ligand and an inorganic ion; and (b) removing the inorganic ions from the bead to form the molecularly imprinted polymer ion exchange resin, the bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in an liquid medium.
    Type: Grant
    Filed: August 11, 2006
    Date of Patent: November 15, 2011
    Assignee: The Johns Hopkins University
    Inventors: George M. Murray, Kelly A. Van Houten, Glen E. Southard
  • Patent number: 7678870
    Abstract: A process is provided herein for preparing molecularly imprinted polymers for detecting a target analyte by Reversible Addition Fragmentation Chain Transfer (RAFT). The process includes providing a complex having the formula L3M wherein L is a ?-diketone ligand containing a chain transfer moiety and L3 can be the same or different ligands, and M is a lanthanide element; reacting the complex with the target analyte to provide an adduct containing the target analyte; co-polymerizing the adduct with a monomer and cross-linking agent to provide a polymer; and removing the target analyte from the polymer to provide the molecularly imprinted polymer.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: March 16, 2010
    Assignee: The Johns Hopkins University
    Inventors: Glen E. Southard, George M. Murray
  • Patent number: 7476316
    Abstract: A method of creating a cationic molecularly imprinted polymer bead that can bind inorganic target compounds is disclosed and described. The cationic molecularly imprinted polymer bead can be formed by complexing a target compound with a cationic ligand, polymerizing the cationic ligands to form the bead, and then extracting the target compound from the bead. The cationic ligand complex can have an octanol water partition coefficient of about 1 to about 10. The cationic molecularly imprinted polymer bead can have a porous structure containing a plurality of complexing cavities for selectively bind specific target compounds for removal from potable water, mine effluent, industrial effluent, or other fluids.
    Type: Grant
    Filed: September 12, 2006
    Date of Patent: January 13, 2009
    Assignee: MIP Solutions, Inc.
    Inventor: Glen E. Southard
  • Publication number: 20080264868
    Abstract: A molecularly imprinted polymer ion exchange resin for selectively removing one or more inorganic ions in a liquid medium is disclosed and described. The exchange resin can include a bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in a liquid medium. A process for preparing a molecularly imprinted polymer ion exchange resin can include (a) polymerizing a polmerizable mixture in the presence of an inorganic ion imprinting complex to form a bead, said inorganic ion imprinting complex including a ligand and an inorganic ion; and (b) removing the inorganic ions from the bead to form the molecularly imprinted polymer ion exchange resin, the bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in an liquid medium.
    Type: Application
    Filed: August 11, 2006
    Publication date: October 30, 2008
    Inventors: George M. Murray, Kelly A. Van Houten, Glen E. Southard
  • Publication number: 20080144002
    Abstract: A molecularly imprinted polymer sensor device for detecting a specific inorganic target ion is disclosed. The device includes at least one or more molecularly imprinted polymer beads comprising a macroporous structure having a plurality of complexing cavities therein, wherein the complexing cavities contain cationic ligands spatially oriented to selectively receive and bind a specific inorganic target ion to be detected and having operatively associated therewith a light source for generating excitation energy of the beads.
    Type: Application
    Filed: December 17, 2007
    Publication date: June 19, 2008
    Inventors: George M. Murray, Glen E. Southard
  • Patent number: 7319038
    Abstract: A food spoilage sensor of the general formula wherein M is a transition metal ion; D1, D2, D3 and D4 can be the same or different and can be N or P; R1 and R2, R3 and R4, R5 and R6, and R7 and R8 can be the same or different and from, taken together with the adjacent carbon atoms to which they are bonded and joined together, an aromatic or a cyclic group with at least one of the aromatic or cyclic groups possessing one or more polymerizable moieties. The complex selectively binds biogenic amines which are released by food spoilage microorganisms and undergo a detectable color change upon exposure thereto.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: January 15, 2008
    Assignee: The Johns Hopkins University
    Inventor: Glen E. Southard
  • Patent number: 7067702
    Abstract: A process for preparing vinyl substituted beta-diketones includes reacting a halogen-containing beta-diketone with an olefin in a reaction zone under Heck coupling reaction conditions in the presence of a catalyst, a base, and an organic phosphine to provide a vinyl substituted beta-diketone product.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: June 27, 2006
    Assignee: The Johns Hopkins University
    Inventors: Glen E. Southard, George M. Murray
  • Publication number: 20040072359
    Abstract: A food spoilage sensor comprising a macrocyclic transition metal complex of the general formula 1
    Type: Application
    Filed: September 17, 2003
    Publication date: April 15, 2004
    Inventor: Glen E. Southard