Patents by Inventor Glen E. Southard
Glen E. Southard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11458453Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.Type: GrantFiled: September 23, 2020Date of Patent: October 4, 2022Assignee: 6TH Wave Innovations Corp.Inventors: Jonathan P. Gluckman, Glen E. Southard
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Patent number: 11389782Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.Type: GrantFiled: November 3, 2017Date of Patent: July 19, 2022Assignee: 6th Wave Innovations Corp.Inventors: Jonathan P. Gluckman, Glen E. Southard
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Publication number: 20210252477Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.Type: ApplicationFiled: September 23, 2020Publication date: August 19, 2021Inventors: Jonathan P. Gluckman, Glen E. Southard
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Patent number: 10814306Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.Type: GrantFiled: June 8, 2016Date of Patent: October 27, 2020Assignee: 6th Wave Innovations Corp.Inventors: Jonathan P. Gluckman, Glen E. Southard
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Publication number: 20180214845Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.Type: ApplicationFiled: June 8, 2016Publication date: August 2, 2018Inventors: Jonathan P. Gluckman, Glen E. Southard
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Publication number: 20180117564Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.Type: ApplicationFiled: November 3, 2017Publication date: May 3, 2018Inventors: Jonathan P. Gluckman, Glen E. Southard
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Patent number: 9504988Abstract: The present disclosure provides Molecularly Imprinted Polymer (MIP) technology for selectively sequestering one or more target molecules from chemical mixtures. Also disclosed herein are MIP beads and methods of making and using thereof.Type: GrantFiled: June 8, 2016Date of Patent: November 29, 2016Assignee: 6th Wave Innovations Corp.Inventors: Jonathan P. Gluckman, Glen E. Southard
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Patent number: 9211107Abstract: A ruggedized hydrogel product that is formulated to withstand the effects of high-energy sterilization procedures, such as gamma beam and electron beam sterilization, without significant structural degradation is disclosed. This enables the hydrogel product to be suitable for use in medical applications where sterile components are required. In one embodiment a ruggedized hydrogel product is disclosed and comprises a gel component, water for hydrating the gel component, and at least one free radical absorber component that is capable of absorbing free radicals produced when the hydrogel product is sterilized via a high-energy sterilization procedure. The free radical absorber component in one embodiment includes potassium metabisulfite and ascorbic acid. The ruggedized hydrogel product can be included with an ultrasound probe to provide an acoustically transparent interface between the probe and the skin of a patient.Type: GrantFiled: November 7, 2012Date of Patent: December 15, 2015Assignee: C. R. Bard, Inc.Inventors: Jeremy B. Cox, Glen E. Southard, Shayne Messerly
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Patent number: 8591842Abstract: A molecularly imprinted polymer ion exchange resin for selectively removing one or more inorganic ions in a liquid medium is disclosed and described. The exchange resin can include a bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in a liquid medium. A process for preparing a molecularly imprinted polymer ion exchange resin can include (a) polymerizing a polmerizable mixture in the presence of an inorganic ion imprinting complex to form a bead, said inorganic ion imprinting complex including a ligand and an inorganic ion; and (b) removing the inorganic ions from the bead to form the molecularly imprinted polymer ion exchange resin, the bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in an liquid medium.Type: GrantFiled: September 27, 2011Date of Patent: November 26, 2013Assignee: The Johns Hopkins UniversityInventors: George M. Murray, Kelly A. Van Houten, Glen E. Southard
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Publication number: 20120012530Abstract: A molecularly imprinted polymer ion exchange resin for selectively removing one or more inorganic ions in a liquid medium is disclosed and described. The exchange resin can include a bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in a liquid medium. A process for preparing a molecularly imprinted polymer ion exchange resin can include (a) polymerizing a polmerizable mixture in the presence of an inorganic ion imprinting complex to form a bead, said inorganic ion imprinting complex including a ligand and an inorganic ion; and (b) removing the inorganic ions from the bead to form the molecularly imprinted polymer ion exchange resin, the bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in an liquid medium.Type: ApplicationFiled: September 27, 2011Publication date: January 19, 2012Applicant: JOHNS HOPKINS UNIVERSITYInventors: George M. Murray, Kelly A. Van Houten, Glen E. Southard
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Patent number: 8058208Abstract: A molecularly imprinted polymer ion exchange resin for selectively removing one or more inorganic ions in a liquid medium is disclosed and described. The exchange resin can include a bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in a liquid medium. A process for preparing a molecularly imprinted polymer ion exchange resin can include (a) polymerizing a polmerizable mixture in the presence of an inorganic ion imprinting complex to form a bead, said inorganic ion imprinting complex including a ligand and an inorganic ion; and (b) removing the inorganic ions from the bead to form the molecularly imprinted polymer ion exchange resin, the bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in an liquid medium.Type: GrantFiled: August 11, 2006Date of Patent: November 15, 2011Assignee: The Johns Hopkins UniversityInventors: George M. Murray, Kelly A. Van Houten, Glen E. Southard
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Patent number: 7678870Abstract: A process is provided herein for preparing molecularly imprinted polymers for detecting a target analyte by Reversible Addition Fragmentation Chain Transfer (RAFT). The process includes providing a complex having the formula L3M wherein L is a ?-diketone ligand containing a chain transfer moiety and L3 can be the same or different ligands, and M is a lanthanide element; reacting the complex with the target analyte to provide an adduct containing the target analyte; co-polymerizing the adduct with a monomer and cross-linking agent to provide a polymer; and removing the target analyte from the polymer to provide the molecularly imprinted polymer.Type: GrantFiled: October 4, 2004Date of Patent: March 16, 2010Assignee: The Johns Hopkins UniversityInventors: Glen E. Southard, George M. Murray
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Patent number: 7476316Abstract: A method of creating a cationic molecularly imprinted polymer bead that can bind inorganic target compounds is disclosed and described. The cationic molecularly imprinted polymer bead can be formed by complexing a target compound with a cationic ligand, polymerizing the cationic ligands to form the bead, and then extracting the target compound from the bead. The cationic ligand complex can have an octanol water partition coefficient of about 1 to about 10. The cationic molecularly imprinted polymer bead can have a porous structure containing a plurality of complexing cavities for selectively bind specific target compounds for removal from potable water, mine effluent, industrial effluent, or other fluids.Type: GrantFiled: September 12, 2006Date of Patent: January 13, 2009Assignee: MIP Solutions, Inc.Inventor: Glen E. Southard
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Publication number: 20080264868Abstract: A molecularly imprinted polymer ion exchange resin for selectively removing one or more inorganic ions in a liquid medium is disclosed and described. The exchange resin can include a bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in a liquid medium. A process for preparing a molecularly imprinted polymer ion exchange resin can include (a) polymerizing a polmerizable mixture in the presence of an inorganic ion imprinting complex to form a bead, said inorganic ion imprinting complex including a ligand and an inorganic ion; and (b) removing the inorganic ions from the bead to form the molecularly imprinted polymer ion exchange resin, the bead having a porous structure and comprising a cross-linked molecularly imprinted polymer having molecular sized cavities adapted to selectively receive and bind a specific inorganic ion in an liquid medium.Type: ApplicationFiled: August 11, 2006Publication date: October 30, 2008Inventors: George M. Murray, Kelly A. Van Houten, Glen E. Southard
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Publication number: 20080144002Abstract: A molecularly imprinted polymer sensor device for detecting a specific inorganic target ion is disclosed. The device includes at least one or more molecularly imprinted polymer beads comprising a macroporous structure having a plurality of complexing cavities therein, wherein the complexing cavities contain cationic ligands spatially oriented to selectively receive and bind a specific inorganic target ion to be detected and having operatively associated therewith a light source for generating excitation energy of the beads.Type: ApplicationFiled: December 17, 2007Publication date: June 19, 2008Inventors: George M. Murray, Glen E. Southard
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Patent number: 7319038Abstract: A food spoilage sensor of the general formula wherein M is a transition metal ion; D1, D2, D3 and D4 can be the same or different and can be N or P; R1 and R2, R3 and R4, R5 and R6, and R7 and R8 can be the same or different and from, taken together with the adjacent carbon atoms to which they are bonded and joined together, an aromatic or a cyclic group with at least one of the aromatic or cyclic groups possessing one or more polymerizable moieties. The complex selectively binds biogenic amines which are released by food spoilage microorganisms and undergo a detectable color change upon exposure thereto.Type: GrantFiled: September 17, 2003Date of Patent: January 15, 2008Assignee: The Johns Hopkins UniversityInventor: Glen E. Southard
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Patent number: 7067702Abstract: A process for preparing vinyl substituted beta-diketones includes reacting a halogen-containing beta-diketone with an olefin in a reaction zone under Heck coupling reaction conditions in the presence of a catalyst, a base, and an organic phosphine to provide a vinyl substituted beta-diketone product.Type: GrantFiled: May 12, 2005Date of Patent: June 27, 2006Assignee: The Johns Hopkins UniversityInventors: Glen E. Southard, George M. Murray
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Publication number: 20040072359Abstract: A food spoilage sensor comprising a macrocyclic transition metal complex of the general formula 1Type: ApplicationFiled: September 17, 2003Publication date: April 15, 2004Inventor: Glen E. Southard