Patents by Inventor Glen L. Tolman

Glen L. Tolman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules
    Patent number: 4732864
    Abstract: Conjugates of target-seeking biologically active molecules and metallothionein in which all or part of the metal in the metallothionein is suitable for diagnostic or therapeutic applications.
    Type: Grant
    Filed: October 6, 1983
    Date of Patent: March 22, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Glen L. Tolman
  • Bifunctional chelating agents
    Patent number: 4575556
    Abstract: Novel homocysteine thiolactone bifunctional chelating agents useful for chelating radionuclides to produce a radiodiagnostic agent for use in in vivo imaging and a method for producing this chelating agent.
    Type: Grant
    Filed: November 28, 1983
    Date of Patent: March 11, 1986
    Assignee: Medi-Physics, Inc.
    Inventors: Edmund F. Byrne, Glen L. Tolman
  • Homocysteine and homocysteinamide derivatives
    Patent number: 4571430
    Abstract: Novel homocysteine thiolactone bifunctional chelating agents useful for chelating radionuclides to produce a radiodiagnostic agent for use in vivo imaging and a method for producing this chelating agent.
    Type: Grant
    Filed: November 28, 1983
    Date of Patent: February 18, 1986
    Assignee: Medi-Physics, Inc.
    Inventors: Edmund F. Byrne, Glen L. Tolman
  • Method for making chromogenic and/or fluorogenic substrates for use in monitoring catalytic or enzymatic activity
    Patent number: 4529796
    Abstract: A method for preparing a substrate capable of undergoing catalytic-induced hydrolysis of the phosphate ester at the 3' position, to yield a species capable of being monitored spectrophotometrically or fluorometrically, comprises(a) forming a mononucleotide 20', 3' cyclic phosphate of the formula: ##STR1## wherein B is a nucleotide base, and wherein the CH.sub.
    Type: Grant
    Filed: February 22, 1982
    Date of Patent: July 16, 1985
    Assignee: Baker Instruments Corporation
    Inventors: Jemo Kang, Glen L. Tolman
  • Bifunctional chelating agents
    Patent number: 4434151
    Abstract: Novel homocysteine thiolactone bifunctional chelating agents useful for chelating radionuclides to produce a radiodiagnostic agent for use in in vivo imaging and a method for producing this chelating agent.
    Type: Grant
    Filed: November 8, 1982
    Date of Patent: February 28, 1984
    Assignee: Medi-Physics, Inc.
    Inventors: Edmund F. Byrne, Glen L. Tolman