Abstract: An apparatus is adapted to centrifuge a container for separating a component, such as fibrin monomer, from blood or plasma. The container includes a cylindrical member, and a piston displaceable therein and a tubular piston rod, which extends through a top wall of the cylindrical member. The piston divides the cylindrical member into a first chamber positioned above the piston between the piston and the top wall, and a second chamber positioned below the piston. The apparatus includes a supporting turntable which releasably retains the cylindrical member. The supporting turntable is connected to a first activator for rotating the supporting turntable with the container about the central axis thereof. The apparatus also includes a rotatably journalled piston activating mechanism adapted to activate the piston by a second activator.

Abstract: An improved plasma separation device and method involve the use of a retaining means with a centrifugal plasma separation device for retaining unwanted blood components, e.g., lipids or lipoproteins, from passing from a separation chamber in the device to a collection chamber in the device along with the separated plasma.