Patents by Inventor Gloria S. Yen

Gloria S. Yen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and systems for performing digital assays using polydisperse droplets
    Patent number: 11939626
    Abstract: Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure.
    Type: Grant
    Filed: July 19, 2022
    Date of Patent: March 26, 2024
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Daniel T. Chiu, Jason E. Kreutz, Gloria S. Yen, Bryant S. Fujimoto
  • METHODS AND SYSTEMS FOR PERFORMING DIGITAL ASSAYS USING POLYDISPERSE DROPLETS
    Publication number: 20220356512
    Abstract: Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure.
    Type: Application
    Filed: July 19, 2022
    Publication date: November 10, 2022
    Applicant: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Daniel T. CHIU, Jason E. KREUTZ, Gloria S. YEN, Bryant S. FUJIMOTO
  • Methods and systems for performing digital assays using polydisperse droplets
    Patent number: 11427857
    Abstract: Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: August 30, 2022
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Daniel T. Chiu, Jason E. Kreutz, Gloria S. Yen, Bryant S. Fujimoto
  • Methods and systems for performing digital measurements
    Patent number: 11401547
    Abstract: Methods and systems for digital measurements are provided. In an embodiment, the method includes producing a plurality of droplets, wherein at least one of the droplets of the plurality of droplets contains an analyte molecule from a sample; measuring at least a first portion of the plurality of droplets to determine individual volumes of droplets in the first portion of the plurality of droplets; analyzing at least a second portion of the plurality of droplets to determine a number of droplets in the second portion of the plurality of droplets that contain the analyte molecule; and using individual volumes of the droplets in the first portion of the plurality of droplets and the number of droplets in the second portion of the plurality of droplets that contain the analyte molecule to determine the concentration of the analyte molecule in the sample.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: August 2, 2022
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Daniel T. Chiu, Bryant S. Fujimoto, Alexander R. Gansen, Gloria S. Yen, Robert M. Lorenz
  • METHODS AND SYSTEMS FOR PERFORMING DIGITAL ASSAYS USING POLYDISPERSE DROPLETS
    Publication number: 20200208202
    Abstract: Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure.
    Type: Application
    Filed: March 6, 2020
    Publication date: July 2, 2020
    Inventors: Daniel T. Chiu, Jason E. Kreutz, Gloria S. Yen, Bryant S. Fujimoto
  • METHODS AND SYSTEMS FOR PERFORMING DIGITAL MEASUREMENTS
    Publication number: 20200157615
    Abstract: Methods and systems for digital measurements are provided. In an embodiment, the method includes producing a plurality of droplets, wherein at least one of the droplets of the plurality of droplets contains an analyte molecule from a sample; measuring at least a first portion of the plurality of droplets to determine individual volumes of droplets in the first portion of the plurality of droplets; analyzing at least a second portion of the plurality of droplets to determine a number of droplets in the second portion of the plurality of droplets that contain the analyte molecule; and using individual volumes of the droplets in the first portion of the plurality of droplets and the number of droplets in the second portion of the plurality of droplets that contain the analyte molecule to determine the concentration of the analyte molecule in the sample.
    Type: Application
    Filed: February 5, 2020
    Publication date: May 21, 2020
    Inventors: Daniel T. CHIU, Bryant S. FUJIMOTO, Alexander R. GANSEN, Gloria S. YEN, Robert M. LORENZ
  • Methods and apparatus for performing digital assays using polydisperse droplets
    Patent number: 10619192
    Abstract: Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: April 14, 2020
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Daniel T. Chiu, Jason E. Kreutz, Gloria S. Yen, Bryant S. Fujimoto
  • Methods and systems for performing digital measurements
    Patent number: 10590470
    Abstract: Methods, devices and systems for performing digital measurements are provided.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: March 17, 2020
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Daniel T. Chiu, Bryant S. Fujimoto, Alexander R. Gansen, Gloria S. Yen, Robert M. Lorenz
  • METHODS AND SYSTEMS FOR PERFORMING DIGITAL MEASUREMENTS
    Publication number: 20180251827
    Abstract: Methods, devices and systems for performing digital measurements are provided.
    Type: Application
    Filed: April 25, 2018
    Publication date: September 6, 2018
    Inventors: Daniel T. CHIU, Bryant S. FUJIMOTO, Alexander R. GANSEN, Gloria S. YEN, Robert M. LORENZ
  • Methods and systems for performing digital measurements
    Patent number: 10000797
    Abstract: Methods, devices and systems for performing digital measurements are provided.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: June 19, 2018
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Daniel T. Chiu, Bryant S. Fujimoto, Alexander R. Gansen, Gloria S. Yen, Robert M. Lorenz
  • METHODS AND APPARATUS FOR PERFORMING DIGITAL ASSAYS USING POLYDISPERSE DROPLETS
    Publication number: 20170175174
    Abstract: Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure.
    Type: Application
    Filed: April 8, 2015
    Publication date: June 22, 2017
    Inventors: Daniel T. CHIU, Jason E. KREUTZ, Gloria S. YEN, Bryant S. FUJIMOTO
  • METHODS AND SYSTEMS FOR PERFORMING DIGITAL MEASUREMENTS
    Publication number: 20170145490
    Abstract: Methods, devices and systems for performing digital measurements are provided.
    Type: Application
    Filed: August 5, 2016
    Publication date: May 25, 2017
    Inventors: Daniel T. Chiu, Bryant S. Fujimoto, Alexander R. Gansen, Gloria S. Yen, Robert M. Lorenz
  • Methods and systems for performing digital measurements
    Patent number: 9428793
    Abstract: Methods, devices and systems for performing digital measurements are provided.
    Type: Grant
    Filed: January 20, 2012
    Date of Patent: August 30, 2016
    Assignee: University of Washington Through Its Center For Commercialization
    Inventors: Daniel T. Chiu, Bryant S. Fujimoto, Alexander R. Gansen, Gloria S. Yen, Robert M. Lorenz
  • METHODS AND SYSTEMS FOR PERFORMING DIGITAL MEASUREMENTS
    Publication number: 20140087386
    Abstract: Methods, devices and systems for performing digital measurements are provided.
    Type: Application
    Filed: January 20, 2012
    Publication date: March 27, 2014
    Applicant: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Daniel T. Chiu, Bryant S. Fujimoto, Alexander R. Gansen, Gloria S. Yen, Robert M. Lorenz