Abstract: A calibration target for calibrating an optoelectronic device for analyzing biomolecules by detecting fluorescence signals from a sample includes a substrate and a solid fluorescent layer that is disposed on the substrate and capable of being excited by laser light. The fluorescent layer has an optically inactive matrix having embedded therein a carbon-based component that is excitable to light emission.

Abstract: A calibration target for calibrating an optoelectronic device for analyzing biomolecules by detecting fluorescence signals from a sample includes a substrate and a solid fluorescent layer that is disposed on the substrate and capable of being excited by laser light. The fluorescent layer has an optically inactive matrix having embedded therein a carbon-based component that is excitable to light emission.

Abstract: A surface coating for a medical instrument includes an interference filter having at least one dielectric layer and at least one metallic layer arranged one above another. At least one of the at least one metallic layer and the at least one dielectric layer is adapted to be structurally altered by action of a corrosive environment on the surface coating such that the surface coating is convertible from a first state to a second state. In the first state, the surface coating has a first spectral reflectivity. In the second state, the surface coating has a second spectral reflectivity that is different from the first spectral reflectivity.

Abstract: A bone implant includes (a) a first layer provided over a first outer surface of the bone implant and being formed of a first material which is one of water-soluble and degradable in body fluids, the first layer having a first thickness and (b) a second layer provided over an outer periphery of the first layer and being formed of a biocompatible material, the second layer having a second thickness smaller than the first thickness.

Abstract: A surface coating for a medical instrument includes an interference filter having at least one dielectric layer and at least one metallic layer arranged one above another. At least one of the at least one metallic layer and the at least one dielectric layer is adapted to be structurally altered by action of a corrosive environment on the surface coating such that the surface coating is convertible from a first state to a second state. In the first state, the surface coating has a first spectral reflectivity. In the second state, the surface coating has a second spectral reflectivity that is different from the first spectral reflectivity.

Abstract: A method for manufacturing a surgical implant. A metal layer is deposited onto a polyaryletherketone (PAEK) substrate by generating a series of pulses using a high power impulse magnetron sputtering process. Each pulse is applied in a series of micro pulse steps comprising (i) micro pulse on steps ranging from 10 ?s to 100 ?s and (ii) micro pulse off steps ranging from 5 ?s as to 400 ?s; at a repetition frequency ranging from 50-2000 Hz with 2 micropulses to 20 micropulses per repetition, a total pulse on time ranging from 25 ?s to 800 ?s for 5 minutes to 300 minutes at averaged power ranging from 200 W to 3000 W. The series of pulses are performed in a unipolar mode or a bipolar mode.

Abstract: A method for joining two or more segments of a bone implant comprises the steps of placing a plurality of thin layers of an intermetallic material between first and second segments of the bone implant and applying a mechanical load to the plurality of layers. In a subsequent step, the plurality of layers are ignited by applying an external activation energy thereto, the ignition heating the plurality of layers to a reaction temperature and causing the segments to become affixed to one another after cooling.

Abstract: A bone implant includes (a) a first layer provided over a first outer surface of the bone implant and being formed of a first material which is one of water-soluble and degradable in body fluids, the first layer having a first thickness and (b) a second layer provided over an outer periphery of the first layer and being formed of a biocompatible material, the second layer having a second thickness smaller than the first thickness.

Abstract: A coating for a CoCrMo substrate including a first layer located directly on the substrate and including Ta(CoCrMo)0.5-2.0, a second layer located directly on the first layer and including tantalum, a third layer located directly on the second layer and including tantalum carbide, and a fourth layer located directly on the third layer and including diamond-like carbon (DLC).

Abstract: A coating for a CoCrMo substrate including a first layer located directly on the substrate and including Ta(CoCrMo)0.5-2.0, a second layer located directly on the first layer and including tantalum, a third layer located directly on the second layer and including tantalum carbide, and a fourth layer located directly on the third layer and including diamond-like carbon (DLC).

Abstract: An orthopedic implant comprising a metallic substrate coated with a diamond-like carbon (DLC) layer, and a layer of a polymeric material placed over the DLC layer that is less stiff than the substrate, and methods of manufacturing the same.

Abstract: A method for manufacturing a surgical implant. A metal layer is deposited onto a polyaryletherketone (PAEK) substrate by generating a series of pulses using a high power impulse magnetron sputtering process. Each pulse is applied in a series of micro pulse steps comprising (i) micro pulse on steps ranging from 10 ?s to 100 ?s and (ii) micro pulse off steps ranging from 5 ?s as to 400 ?s; at a repetition frequency ranging from 50-2000 Hz with 2 micropulses to 20 micropulses per repetition, a total pulse on time ranging from 25 ?s to 800 ?s for 5 minutes to 300 minutes at averaged power ranging from 200 W to 3000 W. The series of pulses are performed in a unipolar mode or a bipolar mode.

Abstract: An orthopedic implant comprising a metallic substrate coated with a diamond-like carbon (DLC) layer, and a layer of a polymeric material placed over the DLC layer that is less stiff than the substrate, and methods of manufacturing the same.

Abstract: An orthopedic implant comprising a metallic substrate coated with a diamond-like carbon (DLC) layer, and a layer of a polymeric material placed over the DLC layer that is less stiff than the substrate, and methods of manufacturing the same.

Abstract: A multilayer article including a thermoplastic layer having a first surface and a second surface opposite the first surface and a base layer have a first base surface and a second base surface opposite the first base surface, wherein the first base surface of the base layer is permanently bonded to the second surface of the thermoplastic layer, wherein the thermoplastic layer has a first glass transition temperature, Tg1, and wherein the multilayer article is rigid at temperatures less than Tg1 and is flexible at temperatures greater than Tg1.

Abstract: A method for joining two or more segments of a bone implant comprises the steps of placing a plurality of thin layers of an intermetallic material between first and second segments of the bone implant and applying a mechanical load to the plurality of layers. In a subsequent step, the plurality of layers are ignited by applying an external activation energy thereto, the ignition heating the plurality of layers to a reaction temperature and causing the segments to become affixed to one another after cooling.

Abstract: A bone implant includes (a) a first layer provided over a first outer surface of the bone implant and being formed of a first material which is one of water-soluble and degradable in body fluids, the first layer having a first thickness and (b) a second layer provided over an outer periphery of the first layer and being formed of a biocompatible material, the second layer having a second thickness smaller than the first thickness.

Abstract: The disclosure relates to an orthopedic implant comprising a metallic substrate coated with a diamond-like carbon (DLC) layer, and a layer of a polymeric material placed over the DLC layer that is less stiff than the substrate, and methods of manufacturing the same.

Abstract: A coating for a CoCrMo substrate including a first layer located directly on the substrate and including Ta(CoCrMo)0.5-2.0, a second layer located directly on the first layer and including tantalum, a third layer located directly on the second layer and including tantalum carbide, and a fourth layer located directly on the third layer and including diamond-like carbon (DLC).