Abstract: A method for controlling a stepper motor includes calculating a duty cycle of a current provided to the stepper motor and comparing a difference, between the calculated duty cycle and a base duty cycle of current provided to the stepper motor under a base load condition, to a reference duty cycle value. The method also includes adjusting a peak current level of the current provided to the stepper motor responsive to the comparison.

Abstract: An apparatus for regulating a slew time of an output voltage of a motor driver system includes a gate current control circuit which has a first input coupled to receive a target slew time and a second input coupled to receive a slew time. The gate current control circuit provides an incremented gate current if the slew time is greater than the target slew time and provides a decremented gate current if the slew time is less than the target slew time. The apparatus includes a gate driver which has a first input coupled to receive a PWM signal and a second input coupled to receive the gate current. The gate driver provides a gate drive signal.

Abstract: The present disclosure provides methods of treating myeloproliferative disorders in patients concurrently receiving a dual CYP2C19 and CYP3A4 inhibitor.

Abstract: Pharmaceutical compositions, and a method of stabilizing pharmaceutical compositions having clevidipine, or any pharmaceutically acceptable salt thereof, as the active ingredient is described. The method includes the slowing down or inhibiting of the oxidation pathway of clevidipine. This can be accomplished by reducing the amount the pharmaceutical composition is exposed to oxygen and/or light during the manufacturing and storing processes. According to this method, oxygen must be removed or replaced, or light must be sufficiently blocked such that light energy cannot reach the active ingredient of the composition, or is reduced to a level that the light-induced oxidation reaction converting clevidipine to H324/78 is minimized, such that the total detectable level of H324/78 in a given composition sample does not exceed about 0.2% on a weight-by-weight basis, or the ratio of clevidipine to H324/78 is equal to or greater than about 450 to 1 on a weight-to-weight basis.

Abstract: A motor control system and method for controlling a brushed direct current (BDC) motor using a feedback loop based on a corrected ripple count. Motor control circuitry, for example implemented in digital logic such as a microcontroller, receives a coil current signal and a motor voltage signal. Discontinuities in the coil current signal, such as caused by commutation of the BDC motor, are counted to generate a ripple count. An observer function derives an angular frequency model estimate for the values of the coil current and motor voltage signals using a computational model for the motor. A corrected ripple count is generated based on a comparison of a commutation angle of the motor with an angular position based on the angular frequency model estimate over a time interval between discontinuity pulses. A motor drive signal is adjusted based on the corrected ripple count.

Abstract: Disclosed herein is an electrolyzer comprising a horizontal cathode located below a suspended anode for purposes of performing electrolysis on metal-bearing mixtures or solutions. The horizontal cathode may comprise the bottom surface of a compartment for containing a mixture or solution of metal components, electrolyte, and/or supplemental chemicals. The horizontal anode may engage the upper surface of the mixture or solution in the compartment. A removal mechanism for facilitating removal of the end-products of the mixture or solution from the compartment (and the surface of the horizontal cathode) through the gate may also be employed. These implementations may be used in recycling of lead acid batteries (LABs) without any need for smelting, and also may be applied to a variety of different electrolytical operations.

Abstract: The present invention relates to pyrimidinium compounds of formula (1), to the stereoisomers, salts, tautomers and N-oxides thereof, their mixtures and to compositions comprising such compounds or mixtures. The invention also relates to methods and uses of these pyrimidinium compounds and of compositions thereof, for combating and controlling animal pests. Furthermore, the invention relates also to pesticidal methods of applying such substituted pyrimidinium compounds. The pyrimidinium compounds of the present invention are defined by the following general formula (I): wherein R1, R2 and Het are defined as in the description.

Abstract: Disclosed is a rupture disc assembly for use in making a temporary seal in a vessel such as a casing string. The rupture disc assembly may include a rupture disc having a side surface that has a shallow angle taper inward towards a bottom surface of the rupture disc, and a mounting apparatus to support the rupture disc so that the rupture disc forms the temporary seal. When a disc working pressure is applied to a top surface of the rupture disc, engagement/force transmission between the rupture disc and the mounting apparatus produces enough radial compression in the rupture disc due to the shallow angle taper to significantly mitigate or cancel tensile stresses thereby avoiding the rupture disc from breaking. The rupture disc may be configured to break when the rupture disc is subjected to a disc working pressure that is greater than the disc rupture pressure, thereby removing the temporary seal.

Abstract: A re-timer device includes transceiver circuitry. The transceiver circuitry includes clock generation circuitry and first receiver circuitry. The clock generation circuitry generates a first clock signal. The first receiver circuitry receives the first clock signal and a first input signal. The first receiver circuitry generates a first frequency offset value based on the first input signal and the first clock signal. The first input signal has a first frequency and the first clock signal has a second frequency different than the first frequency. The first receiver circuitry outputs the first frequency offset value.

Abstract: A stepper motor driver includes an H-bridge including first and second outputs. The H-bridge includes a low-side transistor coupled between the first output and a ground. A reference current circuit is configured to produce a reference current. The reference current circuit has a reference output. An averager circuit includes an input and output. The input of the averager circuit is coupled to the first output of the H-bridge. A comparator includes first and second comparator inputs. The first input of the comparator is coupled to the output of the average circuit and the second input of the comparator is coupled to the reference output.

Abstract: This document describes techniques and devices for a refined search with machine learning. These techniques improve computer-aided searches through enabling selection of search criteria used in a prior search and providing a refined search result based on that selection. Furthermore, a machine-learning component of a search engine can be altered to improve future search results based on the selection and an indication of the desirability of the refined search result.

Abstract: A method for controlling a stepper motor includes calculating a duty cycle of a current provided to the stepper motor and comparing a difference, between the calculated duty cycle and a base duty cycle of current provided to the stepper motor under a base load condition, to a reference duty cycle value. The method also includes adjusting a peak current level of the current provided to the stepper motor responsive to the comparison.

Abstract: The present invention relates to pyrimidinium compounds of formula (I), to the stereoisomers, salts, tautomers and N-oxides thereof, their mixtures and to compositions comprising such compounds or mixtures. The invention also relates to methods and uses of these pyrimidinium compounds and of compositions thereof, for combating and controlling animal pests. Furthermore, the invention relates also to pesticidal methods of applying such substituted pyrimidinium compounds. The pyrimidinium compounds of the present invention are defined by the following general formula (I): wherein R1, R2 and Het are defined as in the description.

Abstract: An apparatus for regulating a slew time of an output voltage of a motor driver system includes a gate current control circuit which has a first input coupled to receive a target slew time and a second input coupled to receive a slew time. The gate current control circuit provides an incremented gate current if the slew time is greater than the target slew time and provides a decremented gate current if the slew time is less than the target slew time. The apparatus includes a gate driver which has a first input coupled to receive a PWM signal and a second input coupled to receive the gate current. The gate driver provides a gate drive signal.

Abstract: A control circuit regulates the propagation delay of a field effect transistor (FET) before the FET transitions to the Miller region by applying a pre-charge current for a fixed duration to the gates of the FET. After the fixed duration, the current is reduced to a lower drive current level which is based on a desired output voltage slew rate. After the FET transitions to the Miller region, the output voltage slews down in accordance with the output voltage slew rate. By regulating the slew-rate of the output voltage in the Miller region and regulating the propagation delay of the FET prior to the Miller region, the control circuit reduces electromagnetic interference (EMI) caused by the switching of the FET, thereby improving electromagnetic compatibility (EMC) of switch mode driver systems without increasing the propagation delay of the FET.

Abstract: The present invention relates to compounds of formula I, wherein the variables are defined as given in the description and claims. The invention further relates to uses, processes and composition for compounds I.

Abstract: This document describes techniques and devices for a refined search with machine learning. These techniques improve computer-aided searches through enabling selection of search criteria used in a prior search and providing a refined search result based on that selection. Furthermore, a machine-learning component of a search engine can be altered to improve future search results based on the selection and an indication of the desirability of the refined search result.

Abstract: The present invention relates to substituted pyrimidinium compounds of formula (I), to the stereoisomers, salts, tautomers and N-oxides thereof and to compositions comprising such compounds. The invention also relates to methods and uses of these substituted pyrimidinium compounds and of compositions thereof, for combating and controlling animal pests. Furthermore the invention relates also to pesticidal methods of applying such substituted pyrimidinium compounds. The substituted pyrimidinium compounds of the present invention are defined by the following general formula (I) wherein X, Y, Z, R1, R2, A and R3 are defined as in the description.

Abstract: The present disclosure relates to methods of treating or alleviating one or more symptoms of mucopolysaccharidoses in a subject, via administering a trehalose formulation to the subject.