Patents by Inventor Gordon D. Webster

Gordon D. Webster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating cancer using interleukin-12p40 variants having improved stability
    Patent number: 9029330
    Abstract: Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have improved stability compared to wild-type mature human IL-12p40 polypeptides.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: May 12, 2015
    Assignee: Merck Patent GmbH
    Inventors: Gordon D. Webster, Suzanne P. McKenzie, Kin-Ming Lo, Pascal André Stein
  • Interleukin-12 P40 Variants with Improved Stability
    Publication number: 20130034518
    Abstract: Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have improved stability compared to wild-type mature human IL-12p40 polypeptides.
    Type: Application
    Filed: May 23, 2012
    Publication date: February 7, 2013
    Applicant: Merck Patent GmbH
    Inventors: Gordon D. Webster, Suzanne P. McKenzie, Kin-Ming Lo, Pascal André Stein
  • Nucleic acids encoding interleukin-12P40 variants with improved stability
    Patent number: 8188248
    Abstract: Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have improved stability compared to wild-type mature human IL-12p40 polypeptides.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: May 29, 2012
    Assignee: Merck Patent GmbH
    Inventors: Gordon D. Webster, Suzanne P. McKenzie, Kin-Ming Lo, Pascal A. Stein
  • INTERLEUKIN-12P40 VARIANTS WITH IMPROVED STABILITY
    Publication number: 20110097792
    Abstract: Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have improved stability compared to wild-type mature human IL-12p40 polypeptides.
    Type: Application
    Filed: December 7, 2010
    Publication date: April 28, 2011
    Applicant: Merck Patent GmbH
    Inventors: Gordon D. Webster, Suzanee P. McKenzie, Kin-Ming Lo, Pascal André Stein
  • Interleukin-12p40 variants with improved stability
    Patent number: 7872107
    Abstract: Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have improved stability compared to wild-type mature human IL-12p40 polypeptides.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: January 18, 2011
    Assignee: Merck Patent GmbH
    Inventors: Gordon D. Webster, Suzanne P. McKenzie, Kin-Ming Lo, Pascal André Stein
  • Reset of peripheral printing devices after a hot plug state
    Patent number: 5379437
    Abstract: A controller in a personal computer operating system continuously monitors for signals indicating continued powering of an attached keyboard, mouse or other pointing device. Loss of this signal is caused by the accidental or intentional loss of power to the external device or by physically disconnecting the device. Absence of the signal causes the setting of a timeout bit in the device status byte. When the attached device signals that it has successfully become re-powered, the initialization program routine of the operating system is recalled so as to return the device to on-line status without requiring a restart of the entire operating system.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: January 3, 1995
    Assignee: International Business Machines Corp.
    Inventors: Joseph Celi, Jr., Gordon D. Webster