Patents by Inventor Gordon S. Mitchell

Gordon S. Mitchell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Trophic factor combinations for nervous system treatment
    Patent number: 7862826
    Abstract: The present invention relates to a composition including an effective amount of at least one of an antimicrobial peptide and a substance having an antimicrobial peptide effect and an effective amount of a neurotrophin. The composition can also include an effective amount of at least one of a growth factor and a neuropeptide. The present invention also relates a method of treating an injury to a nervous system of an animal that includes the steps of identifying the injury to the nervous system and applying to the injury an effective amount of at least one of antimicrobial peptide and a substance having an antimicrobial peptide effect. The method can also include applying an effective amount of one or more trophic factors selected from the group consisting of a growth factor, a neurotrophin, and a neuropeptide to the injury.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: January 4, 2011
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Christopher J. Murphy, Jonathan F. McAnulty, Gordon S. Mitchell, Francis J. Golder
  • Trophic Factor Combinations for Nervous System Treatment
    Publication number: 20090298741
    Abstract: The present invention relates to a composition including an effective amount of at least one of an antimicrobial peptide and a substance having an antimicrobial peptide effect and an effective amount of a neurotrophin. The composition can also include an effective amount of at least one of a growth factor and a neuropeptide. The present invention also relates a method of treating an injury to a nervous system of an animal that includes the steps of identifying the injury to the nervous system and applying to the injury an effective amount of at least one of antimicrobial peptide and a substance having an antimicrobial peptide effect. The method can also include applying an effective amount of one or more trophic factors selected from the group consisting of a growth factor, a neurotrophin, and a neuropeptide to the injury.
    Type: Application
    Filed: May 19, 2008
    Publication date: December 3, 2009
    Inventors: Christopher J. Murphy, Jonathan F. McAnulty, Gordon S. Mitchell, Francis J. Golder
  • SiRNA DELIVERY INTO MAMMALIAN NERVE CELLS
    Publication number: 20090186844
    Abstract: The present invention relates to methods of affecting expression of a target gene, suitably brain-derived neurotrophic factor (BDNF) or related genes in a nerve cell in the central nervous system of a mammal. The method includes formulating and delivering an siRNA composition to a target site on the mammal to affect expression of the target gene in the nerve cell, wherein the target site is cerebrospinal space or muscle tissue innervated by a nerve cell, to down-regulate the target gene. Also disclosed are kits for use in practicing the novel methods of in vivo siRNA.delivery into target cells and gene regulation.
    Type: Application
    Filed: January 10, 2008
    Publication date: July 23, 2009
    Inventors: Gordon S. Mitchell, Tracy Lee Baker-Herman