Patents by Inventor Gosuke Shibahara
Gosuke Shibahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10829800Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.Type: GrantFiled: July 17, 2019Date of Patent: November 10, 2020Assignee: The University of British ColumbiaInventors: Andrea Marziali, Joel Pel, Jason Donald Thompson, Gosuke Shibahara
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Patent number: 10554054Abstract: A battery system includes a battery module that is constituted with a plurality of serially connected battery cells, a plurality of integrated circuits that group the battery cells so as to perform processing on battery cells in each group, a first transmission path through which a command signal is transmitted via a first insulating circuit from a higher-order control circuit that controls the integrated circuits to a highest-order integrated circuit of the integrated circuit, a second transmission path through which a data signal collected by the integrated circuits is transmitted from the highest-order integrated circuit to a lowest-order integrated circuit, and a third transmission path through which the data signal is transmitted from the lowest-order integrated circuit to the higher-order control circuit via a second insulating circuit.Type: GrantFiled: April 10, 2017Date of Patent: February 4, 2020Assignees: Hitachi, Ltd., Hitachi Automotive Systems, Ltd.Inventors: Kenji Kubo, Akihiko Kudo, Mutsumi Kikuchi, Gosuke Shibahara
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Publication number: 20190338342Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.Type: ApplicationFiled: July 17, 2019Publication date: November 7, 2019Applicant: The University of British ColumbiaInventors: Andrea Marziali, Joel Pel, Jason Donald Thompson, Gosuke Shibahara
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Patent number: 10400266Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.Type: GrantFiled: June 2, 2016Date of Patent: September 3, 2019Assignee: The University of British ColumbiaInventors: Andrea Marziali, Joel Pel, Jason Donald Thompson, Gosuke Shibahara
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Patent number: 10202041Abstract: A battery monitoring system, comprises a battery state detection circuit that detects battery states of a plurality of battery cells that are connected in series, based on respective cell voltages of the plurality of battery cells, and a control circuit that monitors state of a battery cell, based on each cell voltage of the plurality of battery cells. The control circuit inputs pseudo voltage information to the battery state detection circuit, and thereby diagnoses whether or not the battery state detection circuit is operating normally.Type: GrantFiled: June 28, 2016Date of Patent: February 12, 2019Assignees: Hitachi, Ltd., Hitachi Automotive Systems, Ltd.Inventors: Akihiko Kudo, Mutsumi Kikuchi, Gosuke Shibahara, Akihiko Emori, Yasuo Uemura, Tatsumi Yamauchi, Kenji Kubo, Masahito Sonehara, Masahiko Amano, Yoshinori Aoshima
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Publication number: 20170214254Abstract: A battery system includes a battery module that is constituted with a plurality of serially connected battery cells, a plurality of integrated circuits that group the battery cells so as to perform processing on battery cells in each group, a first transmission path through which a command signal is transmitted via a first insulating circuit from a higher-order control circuit that controls the integrated circuits to a highest-order integrated circuit of the integrated circuit, a second transmission path through which a data signal collected by the integrated circuits is transmitted from the highest-order integrated circuit to a lowest-order integrated circuit, and a third transmission path through which the data signal is transmitted from the lowest-order integrated circuit to the higher-order control circuit via a second insulating circuit.Type: ApplicationFiled: April 10, 2017Publication date: July 27, 2017Inventors: Kenji KUBO, Akihiko KUDO, Mutsumi KIKUCHI, Gosuke SHIBAHARA
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Patent number: 9647466Abstract: A battery system includes a battery module that is constituted with a plurality of serially connected battery cells, a plurality of integrated circuits that group the battery cells so as to perform processing on battery cells in each group, a first transmission path through which a command signal is transmitted via a first insulating circuit from a higher-order control circuit that controls the integrated circuits to a highest-order integrated circuit of the integrated circuit, a second transmission path through which a data signal collected by the integrated circuits is transmitted from the highest-order integrated circuit to a lowest-order integrated circuit, and a third transmission path through which the data signal is transmitted from the lowest-order integrated circuit to the higher-order control circuit via a second insulating circuit.Type: GrantFiled: June 30, 2009Date of Patent: May 9, 2017Assignees: Hitachi, Ltd., Hitachi Automotive Systems, Ltd.Inventors: Kenji Kubo, Akihiko Kudo, Mutsumi Kikuchi, Gosuke Shibahara
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Patent number: 9512477Abstract: The invention discloses methods and apparatus for characterizing trace nucleic acids that are biomarkers for disease. The methods and apparatus provide increased sensitivity to such trace nucleic acids, and allow analysis of nucleic acids present in a sample at only 0.01% of the wild-type sequences. The methods and apparatus are also designed for straightforward multiplexing, thus allowing pooling of clinical samples.Type: GrantFiled: May 3, 2013Date of Patent: December 6, 2016Assignees: Boreal Genomics Inc., The University of British ColumbiaInventors: Andrea Marziali, Matthew Wiggin, Gosuke Shibahara, Valentina S. Vysotskaia
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Publication number: 20160303977Abstract: A battery monitoring system, comprises a battery state detection circuit that detects battery states of a plurality of battery cells that are connected in series, based on respective cell voltages of the plurality of battery cells, and a control circuit that monitors state of a battery cell, based on each cell voltage of the plurality of battery cells. The control circuit inputs pseudo voltage information to the battery state detection circuit, and thereby diagnoses whether or not the battery state detection circuit is operating normally.Type: ApplicationFiled: June 28, 2016Publication date: October 20, 2016Inventors: Akihiko KUDO, Mutsumi KIKUCHI, Gosuke SHIBAHARA, Akihiko EMORI, Yasuo UEMURA, Tatsumi YAMAUCHI, Kenji KUBO, Masahito SONEHARA, Masahiko AMANO, Yoshinori AOSHIMA
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Publication number: 20160289744Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.Type: ApplicationFiled: June 2, 2016Publication date: October 6, 2016Inventors: Andrea Marziali, Joel Pel, Jason Donald Thompson, Gosuke Shibahara
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Patent number: 9434938Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.Type: GrantFiled: August 16, 2013Date of Patent: September 6, 2016Assignee: The University of British ColumbiaInventors: Andrea Marziali, Joel Pel, Jason Donald Thompson, Gosuke Shibahara
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Patent number: 9404975Abstract: A battery monitoring system, comprises a battery state detection circuit that detects battery states of a plurality of battery cells that are connected in series, based on respective cell voltages of the plurality of battery cells, and a control circuit that monitors state of a battery cell, based on each cell voltage of the plurality of battery cells. The control circuit inputs pseudo voltage information to the battery state detection circuit, and thereby diagnoses whether or not the battery state detection circuit is operating normally.Type: GrantFiled: February 12, 2014Date of Patent: August 2, 2016Assignees: Hitachi, Ltd., Hitachi Automotive Systems, Ltd.Inventors: Akihiko Kudo, Mutsumi Kikuchi, Gosuke Shibahara, Akihiko Emori, Yasuo Uemura, Tatsumi Yamauchi, Kenji Kubo, Masahito Sonehara, Masahiko Amano, Yoshinori Aoshima
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Patent number: 9035611Abstract: A battery system for a vehicle is provided with discharge circuits (R1, 129A through 129D, 128A through 128D) that discharge battery cells (BC1 through BC4) via measurement lines of those battery cells (BC1 through BC4).Type: GrantFiled: February 18, 2010Date of Patent: May 19, 2015Assignees: Hitachi, Ltd., Hitachi Automotive Systems, Ltd.Inventors: Mutsumi Kikuchi, Akihiko Kudo, Gosuke Shibahara, Yoshinori Aoshima, Kenji Kubo, Yasuo Uemura
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Patent number: 8829717Abstract: A battery control device for a battery module includes a plurality of integrated circuits. Each integrated circuit includes: a constant voltage circuit that lowers a total voltage of a battery cell group corresponding to the integrated circuit to an integrated circuit internal voltage; a signal generation circuit that generates, based upon a first signal provided by a higher-order control circuit, a second signal assuming a wave height value different from a wave height value of the first signal and outputs the second signal; and a startup circuit that includes a first comparator assuming a first decision-making threshold value corresponding to the first signal and a second comparator assuming a second decision-making threshold value corresponding to the second signal, and starts up the constant voltage circuit in response to a change in an output from at least either the first comparator or the second comparator.Type: GrantFiled: February 3, 2011Date of Patent: September 9, 2014Assignee: Hitachi Vehicle Energy, Ltd.Inventors: Akihiko Kudo, Mutsumi Kikuchi, Gosuke Shibahara, Akihiko Emori, Yasuo Uemura, Tatsumi Yamauchi, Kenji Kubo, Yoshinori Aoshima
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Publication number: 20140159739Abstract: A battery monitoring system, comprises a battery state detection circuit that detects battery states of a plurality of battery cells that are connected in series, based on respective cell voltages of the plurality of battery cells, and a control circuit that monitors state of a battery cell, based on each cell voltage of the plurality of battery cells. The control circuit inputs pseudo voltage information to the battery state detection circuit, and thereby diagnoses whether or not the battery state detection circuit is operating normally.Type: ApplicationFiled: February 12, 2014Publication date: June 12, 2014Applicants: Hitachi Vehicle Energy, Ltd., Hitachi, Ltd.Inventors: Akihiko KUDO, Mutsumi KIKUCHI, Gosuke SHIBAHARA, Akihiko EMORI, Yasuo UEMURA, Tatsumi YAMAUCHI, Kenji KUBO, Masahito SONEHARA, Masahiko AMANO, Yoshinori AOSHIMA
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Patent number: 8723527Abstract: A battery monitoring system, comprises a battery state detection circuit that detects battery states of a plurality of battery cells that are connected in series, based on respective cell voltages of the plurality of battery cells, and a control circuit that monitors state of a battery cell, based on each cell voltage of the plurality of battery cells. The control circuit inputs pseudo voltage information to the battery state detection circuit, and thereby diagnoses whether or not the battery state detection circuit is operating normally.Type: GrantFiled: February 25, 2010Date of Patent: May 13, 2014Assignees: Hitachi, Ltd., Hitachi Vehicle Energy, Ltd.Inventors: Akihiko Kudo, Mutsumi Kikuchi, Gosuke Shibahara, Akihiko Emori, Yasuo Uemura, Tatsumi Yamauchi, Kenji Kubo, Masahito Sonehara, Masahiko Amano, Yoshinori Aoshima
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Publication number: 20130323742Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.Type: ApplicationFiled: August 16, 2013Publication date: December 5, 2013Applicant: THE UNIVERSITY OF BRITISH COLUMBIAInventors: Andrea Marziali, Joel Pel, Jason Donald Thompson, Gosuke Shibahara
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Publication number: 20130296176Abstract: The invention discloses methods and apparatus for characterizing trace nucleic acids that are biomarkers for disease. The methods and apparatus provide increased sensitivity to such trace nucleic acids, and allow analysis of nucleic acids present in a sample at only 0.01% of the wild-type sequences. The methods and apparatus are also designed for straightforward multiplexing, thus allowing pooling of clinical samples.Type: ApplicationFiled: May 3, 2013Publication date: November 7, 2013Inventors: Andrea Marziali, Matthew Wiggin, Gosuke Shibahara, Valentina Semenovna Vysotskaia
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Patent number: 8518570Abstract: A battery system includes: a battery unit formed by electrically connected in series a plurality of cell groups each made up with a plurality of battery cells electrically connected in series; a plurality of sensing lines for detecting voltages of respective battery cells in the battery unit; an integrated circuit provided to each of the cell group, to which the sensing lines for detecting voltages of respective battery cells in the cell group are connected; a case having housed therein a substrate at which a plurality of integrated circuits provided for the cell groups respectively are mounted; noise protection capacitors disposed between input terminals of the plurality of sensing lines; and at least one protection element against static electricity which is connected between the input terminals and the case.Type: GrantFiled: February 12, 2010Date of Patent: August 27, 2013Assignees: Hitachi, Ltd., Hitachi Vehicle Energy, Ltd.Inventors: Akihiko Kudo, Gosuke Shibahara, Mutsumi Kikuchi, Satoru Shigeta
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Patent number: 8518228Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.Type: GrantFiled: June 3, 2011Date of Patent: August 27, 2013Assignee: The University of British ColumbiaInventors: Andrea Marziali, Joel Pel, Jason Donald Thompson, Gosuke Shibahara