Patents by Inventor Gottfried Kraus

Gottfried Kraus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manufacture of surfactant-containing compositions with enhanced stability
    Patent number: 11524070
    Abstract: Improved methods for the manufacture of pharmaceutical compositions comprising at least one surfactant, involving prefiltration of the surfactant prior to formulation into final products.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: December 13, 2022
    Assignee: NOVARTIS AG
    Inventor: Gottfried Kraus
  • HYDROPHILIC FILTRATION DURING MANUFACTURE OF VACCINE ADJUVANTS
    Publication number: 20210077395
    Abstract: An improved method for the manufacture of an oil-in-water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) micro fluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration of the microfluidized emulsion through a hydrophilic membrane. The emulsions are useful as vaccine adjuvants.
    Type: Application
    Filed: September 9, 2020
    Publication date: March 18, 2021
    Inventors: Gottfried Kraus, Robert Eskes
  • MANUFACTURE OF SURFACTANT-CONTAINING COMPOSITIONS WITH ENHANCED STABILITY
    Publication number: 20200353074
    Abstract: Improved methods for the manufacture of pharmaceutical compositions comprising at least one surfactant, involving prefiltration of the surfactant prior to formulation into final products.
    Type: Application
    Filed: December 9, 2019
    Publication date: November 12, 2020
    Inventor: Gottfried Kraus
  • Hydrophilic filtration during manufacture of vaccine adjuvants
    Patent number: 10799454
    Abstract: An improved method for the manufacture of an oil-in water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) micro fluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration, of the microfluidized emulsion through a hydrophilic membrane. The emulsions are useful as vaccine adjuvants.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: October 13, 2020
    Assignee: NOVARTIS AG
    Inventors: Gottfried Kraus, Robert Eskes
  • Manufacture of surfactant-containing compositions with enhanced stability
    Patent number: 10500272
    Abstract: Improved methods for the manufacture of pharmaceutical compositions comprising at least one surfactant, involving prefiltration of the surfactant prior to formulation into final products.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: December 10, 2019
    Assignee: NOVARTIS AG
    Inventor: Gottfried Kraus
  • MANUFACTURE OF SURFACTANT-CONTAINING COMPOSITIONS WITH ENHANCED STABILITY
    Publication number: 20190209678
    Abstract: Improved methods for the manufacture of pharmaceutical compositions comprising at least one surfactant, involving prefiltration of the surfactant prior to formulation into final products.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 11, 2019
    Inventor: Gottfried Kraus
  • HYDROPHILIC FILTRATION DURING MANUFACTURE OF VACCINE ADJUVANTS
    Publication number: 20190201337
    Abstract: An improved method for the manufacture of an oil-in water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) micro fluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration, of the microfluidized emulsion through a hydrophilic membrane. The emulsions are useful as vaccine adjuvants.
    Type: Application
    Filed: January 3, 2019
    Publication date: July 4, 2019
    Inventors: Gottfried Kraus, Robert Eskes
  • Manufacture of surfactant-containing compositions with enhanced stability
    Patent number: 10238739
    Abstract: Improved methods for the manufacture of pharmaceutical compositions comprising at least one surfactant, involving prefiltration of the surfactant prior to formulation into final products.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: March 26, 2019
    Assignee: NOVARTIS AG
    Inventor: Gottfried Kraus
  • Hydrophilic filtration during manufacture of vaccine adjuvants
    Patent number: 10213383
    Abstract: An improved method for the manufacture of an oil-in-water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) micro fluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration of the microfluidized emulsion through a hydrophilic membrane. The emulsions are useful as vaccine adjuvants.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: February 26, 2019
    Assignee: NOVARTIS AG
    Inventors: Gottfried Kraus, Robert Eskes
  • MANUFACTURE OF SURFACTANT-CONTAINING COMPOSITIONS
    Publication number: 20170312357
    Abstract: Improved methods for the manufacture of pharmaceutical compositions comprising at least one surfactant, involving prefiltration of the surfactant prior to formulation into final products.
    Type: Application
    Filed: December 2, 2015
    Publication date: November 2, 2017
    Inventor: Gottfried KRAUS
  • Methods for producing vaccine adjuvants
    Patent number: 8678184
    Abstract: An improved method for the manufacture of an oil-in-water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) microfluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration of the microfluidized emulsion through a hydrophilic membrane. The emulsions are useful as vaccine adjuvants.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: March 25, 2014
    Assignee: Novartis AG
    Inventors: Gottfried Kraus, Robert Eskes
  • HYDROPHILIC FILTRATION DURING MANUFACTURE OF VACCINE ADJUVANTS
    Publication number: 20130129786
    Abstract: An improved method for the manufacture of an oil-in-water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) micro fluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration of the microfluidized emulsion through a hydrophilic membrane. The emulsions are useful as vaccine adjuvants.
    Type: Application
    Filed: December 3, 2010
    Publication date: May 23, 2013
    Applicant: Novartis AG
    Inventors: Gottfried Kraus, Robert Eskes
  • Methods for producing vaccine adjuvants
    Publication number: 20110162982
    Abstract: An improved method for the manufacture of an oil-in-water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) microfluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration of the microfluidized emulsion through a hydrophilic membrane. The emulsions are useful as vaccine adjuvants.
    Type: Application
    Filed: December 3, 2010
    Publication date: July 7, 2011
    Applicant: Novartis Vaccines and Diagnostic, GmbH & Co. KG
    Inventors: Gottfried Kraus, Robert Eskes