Patents by Inventor Gottfried Schepky
Gottfried Schepky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130309307Abstract: The present invention relates to a bilayer pharmaceutical tablet comprising a first layer formulated for immediate release of the angiotensin II receptor antagonist telmisartan from a dissolving tablet matrix which contains telmisartan in substantially amorphous form, and a second layer formulated for immediate release of a diuretic like hydrochlorothiazide from a fast disintegrating tablet matrix. A method of producing the bilayer tablet is also disclosed.Type: ApplicationFiled: July 22, 2013Publication date: November 21, 2013Applicant: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KGInventors: Thomas FRIEDL, Gottfried SCHEPKY
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Publication number: 20090227802Abstract: The present invention relates to a bilayer pharmaceutical tablet comprising a first layer formulated for immediate release of the angiotensin II receptor antagonist telmisartan from a dissolving tablet matrix which contains telmisartan in substantially amorphous form, and a second layer formulated for immediate release of a diuretic like hydrochlorothiazide from a fast disintegrating tablet matrix. A method of producing the bilayer tablet is also disclosed.Type: ApplicationFiled: May 13, 2009Publication date: September 10, 2009Inventors: Thomas FRIEDL, Gottfried Schepky
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Publication number: 20050089575Abstract: The present invention relates to a bilayer pharmaceutical tablet comprising a first layer formulated for immediate release of the angiotensin II receptor antagonist telmisartan from a dissolving tablet matrix which contains telmisartan in substantially amorphous form, and a second layer formulated for immediate release of a diuretic like hydrochlorothiazide from a fast disintegrating tablet matrix. A method of producing the bilayer tablet is also disclosed.Type: ApplicationFiled: July 15, 2004Publication date: April 28, 2005Applicant: Boehringer Ingelheim Pharma GmbH & Co. KGInventors: Thomas Friedl, Gottfried Schepky
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Patent number: 5364646Abstract: Pharmaceutical forms of pimobendan for oral administration comprising citric acid, whereby a constant, satisfactory resorption is ensured even when there are major pH fluctuations in the gastrointestinal tract.Type: GrantFiled: March 16, 1993Date of Patent: November 15, 1994Assignee: Dr. Karl Thomae GmbHInventors: Peter Gruber, Willy Roth, Gottfried Schepky
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Patent number: 4873080Abstract: Galenic compositions containing an oral antidiabetic agent and having an improved release of active substance as well as processes for producing these compositions are provided. The pharmaceutical compositions are characterized in that the onset of the activity and the duration of activity are adapted to the particular needs of diabetics with regard to proper control of metabolism and the associated proper release of insulin. A basic or acidic excipient in a solvent is added to the anti-diabetically active substance in a quantity such that the active substance is made soluble, and then a solubilizing agent is added. The solution is applied to a water-insoluble carrier, the solvent is evaporated, and the residue is further processed to yield the various compositions.Type: GrantFiled: September 30, 1987Date of Patent: October 10, 1989Assignee: Dr. Karl Thomae GmbHInventors: Rolf Brickl, Gottfried Schepky, Eckhard Rupprecht, Andreas Greischel
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Patent number: 4863724Abstract: Galenic compositions containing an oral antidiabetic agent and having an improved release of active substance are provided, as well as processes for producing these compositions. The compositions are characterized in that the onset of the activity and the duration of activity are adapted to the particular needs of diabetics with regard to proper control of the metabolism and the associated proper release of insulin. A basic or acidic excipient in a solvent is added to the antidiabetic active substance in a quantity such that the active substance is made soluble, and then a solubilizing agent is added. Polyvinylpyrrolidone is dissolved as carrier in this solution, but the carrier may simultaneously serve as the solubilizing adjuvant. This solution is further processed with other excipients to form pharmaceutical compositions.Type: GrantFiled: July 23, 1987Date of Patent: September 5, 1989Assignee: Dr. Karl Thomae GmbHInventors: Gottfried Schepky, Rolf Brickl, Eckhard Rupprecht, Andreas Greischel
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Patent number: 4708868Abstract: This invention is directed to novel galenic preparation forms for providing an oral anti-diabetic agent having an improved release of active substance and to processes for producing these preparation forms. The pharmaceutical compositions are characterized in that the onset of the activity and the duration of activity are adapted to the particular needs of diabetics with regard to proper control of metabolism and the associated proper release of insulin. A basic or acidic excipient in a solvent is added to the anti-diabetically active substance in a quantity such that the active substance is made soluble, and then a solubilizing agent is added. The solution is applied to a water-insoluble carrier, the solvent is evaporated, and the residue is further processed to yield the various preparation forms.Type: GrantFiled: May 31, 1984Date of Patent: November 24, 1987Assignee: Dr. Karl Thomae GmbHInventors: Rolf Brickl, Gottfried Schepky, Eckhard Rupprecht, Andreas Greischel
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Patent number: 4696815Abstract: The invention is directed to novel galenic preparation forms for providing an oral anti-diabetic agent having an improved release of active substance and processes for producing these preparation forms. The novel pharmaceutical compositions are characterized in that the onset of the activity and the duration of activity are adapted to the particular needs of diabetics with regard to proper control of the metabolism and the associated proper release of insulin. A basic or acidic excipient in a solvent is added to the anti-diabetic active substance in a quantity such that the active substance is made soluble, and then a solubilizing agent is added. Polyvinyl pyrrolidone is dissolved as carrier in this solution, but the carrier may simultaneously serve as the solubilizing adjuvant. This solution is further processed with other excipients to form corresponding preparation forms.Type: GrantFiled: May 31, 1984Date of Patent: September 29, 1987Inventors: Gottfried Schepky, Rolf Brickl, Eckhard Rupprecht, Andreas Greischel
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Patent number: 4650664Abstract: This invention relates to vehicles for the administration of mopidamol. More specifically, this invention relates to a method of treating cardiovascular disorders, malignancy, or thrombosis in a host in need of such treatment which comprises administering to said host a cardiovascularly, antimetastic, or antithrombotic effective amount of a composition comprised of (i) mopidamol or an acid addition salt thereof and (ii) at least one pharmacologically acceptable acid or acid substance, the total amount of acid from acid addition salt present and acid or acid substance being in a ratio of at least about 1 acid equivalent to 1 mol of mopidamol or its acid addition salt.Type: GrantFiled: September 3, 1985Date of Patent: March 17, 1987Assignee: Dr. Karl Thomae GmbHInventors: Gottfried Schepky, Rolf Brickl, Peter Gruber, Jochen Schmid, Ursula Springmeier
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Patent number: 4596705Abstract: This invention relates to vehicles for the administration of mopidamol. More specifically, this invention relates to a method of treating cardiovascular disorders, malignancy, or thrombosis in a host in need of such treatment which comprises administering to said host a cardiovascularly, antimetastic, or antithrombotic effective amount of a composition comprised of (i) mopidamol or an acid addition salt thereof and (ii) at least one pharmacologically acceptable acid or acid substance, the total amount of acid from acid addition salt present and acid or acid substance being in a ratio of at least about 1 acid equivalent to 1 mol of mopidamol.Type: GrantFiled: October 7, 1983Date of Patent: June 24, 1986Assignee: Dr. Karl Thomae GmbHInventors: Gottfried Schepky, Rolf Brickl, Peter Gruber, Jochen Schmid, Ursula Springmeier
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Patent number: 4427648Abstract: This invention relates to vehicles for the administration of dipyridamole. More specifically, this invention relates to a method of treating cardiovascular disorders in a host in need of such treatment which comprises administering to said host a cardiovascularly effective amount of a composition comprised of (i) dipyridamole or an acid addition salt thereof and (ii) at least one pharmacologically acceptable acid or acid substance, the total amount of acid from acid addition salt present and acid or acid substance being in a ratio of at least about 5 acid equivalents to 1 mol of dipyridamole, preferably in the form of particles having particle sizes of from about 0.1 to 2.0 mm.Type: GrantFiled: June 17, 1982Date of Patent: January 24, 1984Assignee: Dr. Karl Thomae GmbHInventors: Rolf Brickl, Peter Gruber, Gottfried Schepky, Gerhard Bozler