Patents by Inventor Govindan Rajamohan

Govindan Rajamohan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7642069
    Abstract: An improved process for the production of streptokinase using a genetically engineered strain of Escherichia coli which overproduces streptokinase intracellularly and more particularly, the overall process disclosed herein, concerns with an improvement in the fermentative production of streptokinase using an optimized growth medium mainly comprised of simple salts and trace-elements; thus, in principal, the present process constitutes an improved and more economical means for the production of streptokinase which may be useful in thrombolytic therapy.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: January 5, 2010
    Assignee: Council of Scientific & Industrial Research
    Inventors: Vinay Venkatrao Vyas, Govindan Rajamohan, Ramandeep, Kanak Lata Dikshit
  • Patent number: 7524644
    Abstract: The present invention relates to a nucleotide sequence of expression cassette OXY-1 of SEQ ID No. 1, a modified staphylokinase SAK-2 gene of SEQ ID No. 2, a peptide sequence of modified staphylokinase SAK-2 gene, of SEQ ID No. 3, three plasmids having International Deposition Nos. BPL-0019, BPL-0020, and BPL-0021, and their corresponding three recombinant E. Coli; also invention relates to a process for over-producing staphylokinase and its analogues by modulating level of oxygen of its growth medium in a host system, and lastly, a method of dissolving blood clot in a subject in need thereof.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: April 28, 2009
    Assignee: Council of Scientific and Industrial Research
    Inventors: Govindan Rajamohan, Monika Dahiya, Ranjana Pathania, Kanak Lata Dikshit
  • Patent number: 7189557
    Abstract: An improved process for the production of streptokinase using a genetically engineered strain of Escherichia coli which overproduces streptokinase intracellularly and more particularly, the overall process disclosed herein, concerns with an improvement in the fermentative production of streptokinase using an optimized growth medium mainly comprised of simple salts and trace-elements; thus, in principal, the present process constitutes an improved and more economical means for the production of streptokinase which may be useful in thrombolytic therapy.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: March 13, 2007
    Assignee: Council of Scientific & Industrial Research
    Inventors: Vinay Venkatrao Vyas, Govindan Rajamohan, Ramandeep, Kanak Lata Dikshit
  • Publication number: 20060088925
    Abstract: An improved process for the production of streptokinase using a genetically engineered strain of Escherichia coli which overproduces streptokinase intracellularly and more particularly, the overall process disclosed herein, concerns with an improvement in the fermentative production of streptokinase using an optimized growth medium mainly comprised of simple salts and trace-elements; thus, in principal, the present process constitutes an improved and more economical means for the production of streptokinase which may be useful in thrombolytic therapy.
    Type: Application
    Filed: December 9, 2005
    Publication date: April 27, 2006
    Applicant: Council of Scientific & Industrial Research
    Inventors: Vinay Vyas, Govindan Rajamohan, Ramandeep, Kanak Dikshit
  • Publication number: 20050142653
    Abstract: An improved process for the production of streptokinase using a genetically engineered strain of Escherichia coli which overproduces streptokinase intracellularly and more particularly, the overall process disclosed herein, concerns with an improvement in the fermentative production of streptokinase using an optimized growth medium mainly comprised of simple salts and trace-elements; thus, in principal, the present process constitutes an improved and more economical means for the production of streptokinase which may be useful in thrombolytic therapy.
    Type: Application
    Filed: December 29, 2003
    Publication date: June 30, 2005
    Applicant: Council of Scientific & Industrial Research
    Inventors: Vinay Vyas, Govindan Rajamohan, Ramandeep, Kanak Dikshit
  • Publication number: 20050019862
    Abstract: The present invention relates to a nucleotide sequence of expression cassette OXY-1 of SEQ ID No. 1, a modified staphylokinase SAK-2 gene of SEQ ID No. 2, a peptide sequence of modified staphylokinase SAK-2 gene, of SEQ ID No. 3, three plasmids having International Deposition Nos. BPL-0019, BPL-0020, and BPL-0021, and their corresponding three recombinant E. Coli; also invention relates to a process for over-producing staphylokase and its analogues by modulating level of oxygen of its growth medium in a host system, and lastly, a method of dissolving blood clot in a subject in need thereof.
    Type: Application
    Filed: March 31, 2004
    Publication date: January 27, 2005
    Inventors: Govindan Rajamohan, Monika Dahiya, Ranjana Pathania, Kanak Dikshit