Patents by Inventor Grégoire COURTINE

Grégoire COURTINE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11992684
    Abstract: The present invention relates to systems and methods for planning and/or providing neuromodulation One example system includes a stimulation related basic data storage module for storing stimulation related basic data, a stimulation related response data storage module for storing the stimulation related response data, a transfer module configured such that the stimulation related basic data are linked with and/or translated into the response data and/or artificial response data created by the transfer module, wherein the data generated by the transfer module are transfer data, the transfer data comprising link data and/or translation data and/or artificial response data, mapping module configured and arranged such that based on the stimulation related basic data and stimulation related response data and the transfer data a digital characteristic map is generated, and an analysis module configured and arranged such that the digital characteristic map is analyzed automatically.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: May 28, 2024
    Assignees: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), ONWARD MEDICAL N.V.
    Inventors: Karen Minassian, Fabien Wagner, Marco Capogrosso, Gregoire Courtine, Robin Brouns, Jurriaan Bakker, Andre Kleibeuker, Bert Bakker, Vincent Delattre
  • Patent number: 11911621
    Abstract: The present disclosure provides devices, systems, and methods for spinal cord stimulation. In some exemplary embodiments, a lead is provided. In one exemplary embodiment, the lead includes a paddle and an electrode array distributed in the paddle. The electrode array includes a first column of electrodes and a second column of electrodes. The first column of electrodes and the second column of electrodes are symmetric about the midline of the paddle. The first column of electrodes includes a first electrode, a second electrode, and a third electrode. The second column of electrodes includes a fourth electrode corresponding to the first electrode, a fifth electrode corresponding to the second electrode, and a sixth electrode corresponding to the third electrode. A vertical inter-electrode distance between the first electrode and the second electrode is larger than that between the second electrode and the third electrode.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: February 27, 2024
    Assignees: ONWARD MEDICAL N.V., ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
    Inventors: Damien Ganty, Edoardo Paoles, Jocelyne Bloch, Gregoire Courtine, Leonie Asboth, Robin Demesmaeker, Henri Lorach, Jordan Squair, Tomislav Milekovic, Andreas Rowald
  • Publication number: 20230329567
    Abstract: An implantable blood pressure monitor has two or more elements configured to wrap at least part way around a blood vessel. Changes in pressure within the blood vessel may be sensed by detecting movements of the elements or forces applied to the elements. A blood pressure monitor may be implanted without surgery. The blood pressure monitor may transmit real time blood pressure information to a receiver by wireless data transmission.
    Type: Application
    Filed: November 18, 2022
    Publication date: October 19, 2023
    Inventors: Grégoire COURTINE, Aaron PHILLIPS, Jordan SQAIR, David DARROW
  • Patent number: 11691015
    Abstract: The present disclosure relates to a system for neuromodulation and/or neurostimulation, for the treatment of a subject. The system comprises a stimulation controller, a stimulation pattern storage means including stimulation data connected to the stimulation controller, an electrical stimulation device and electrical interface between the electrical stimulation device and the subject, the electrical interface being connectable with a bio-interface of the nervous system of the subject. The stimulation data are pre-programmed patterns comprising spatial and temporal components, The stimulation controller sends configuration signals on the basis of the stimulation data to the electrical stimulation device such that via the electrical interface electrical stimulation is provided to the bio-interface, wherein the electrical stimulation provided is characterized by stimulation parameters that vary over time in a pre-programmed manner.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: July 4, 2023
    Assignee: Onward Medical N.V.
    Inventors: Karen Minassian, Fabien Wagner, Grégoire Courtine
  • Patent number: 11571565
    Abstract: The present invention relates to an electrode array for neuromodulation, comprising a first electrode section with more than two electrodes being arranged parallel and densely packed in the first electrode section, further comprising a second electrode section with more electrodes than in the first electrode section, the electrodes in the second electrode section being arranged symmetrically with respect to the longitudinal axis and transversal offset to each other. Furthermore, the present invention relates to a lead paddle and a neuromodulation system.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: February 7, 2023
    Assignee: Onward Medical N.V.
    Inventors: Marco Capogrosso, Fabien Wagner, Gregoire Courtine, Vincent Delattre, Karen Minassian, Bert Bakker, Jocelyne Bloch, Nathan Greiner, Damien Ganty, Sjaak Deckers, Edoardo Paoles
  • Publication number: 20220409899
    Abstract: The present disclosure provides devices, systems, and methods for spinal cord stimulation. In some exemplary embodiments, a lead is provided. In one exemplary embodiment, the lead includes a paddle and an electrode array distributed in the paddle. The electrode array includes a first column of electrodes and a second column of electrodes. The first column of electrodes and the second column of electrodes are symmetric about the midline of the paddle. The first column of electrodes includes a first electrode, a second electrode, and a third electrode. The second column of electrodes includes a fourth electrode corresponding to the first electrode, a fifth electrode corresponding to the second electrode, and a sixth electrode corresponding to the third electrode. A vertical inter-electrode distance between the first electrode and the second electrode is larger than that between the second electrode and the third electrode.
    Type: Application
    Filed: June 24, 2021
    Publication date: December 29, 2022
    Applicants: ONWARD MEDICAL B.V., ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
    Inventors: Damien Ganty, Edoardo Paoles, Jocelyne Bloch, Gregoire Courtine, Leonie Asboth, Robin Demesmaeker, Henri Lorach, Jordan Squair, Tomislav Milekovic, Andreas Rowald
  • Patent number: 11511116
    Abstract: The present invention relates to systems and methods for planning and/or providing neuromodulation. An example system includes a first data input module for stimulation related basic data, a second data input module for stimulation related response data, a transfer module configured and arranged such that the stimulation related basic data received by the data input module are linked and/or translated into and/or with the response data and/or artificial response data created by the transfer module, wherein the data generated by the transfer module are transfer data, the transfer data comprising link data and/or translation data and/or artificial response data, and a mapping module configured and arranged such that based on the stimulation related basic data and stimulation related response data and the transfer data a digital characteristic map is generated, which describes an interrelation between the stimulation related basic data and the stimulation related response data and the transfer data.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: November 29, 2022
    Assignees: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), ONWARD Medical N.V.
    Inventors: Fabien Wagner, Karen Minassian, Marco Capogrosso, Gregoire Courtine, Robin Brouns, Jurriaan Bakker, Andre Kleibeuker, Bert Bakker, Vincent Delattre
  • Patent number: 11420062
    Abstract: The present disclosure relates to a neuromodulation and/or neurostimulation system comprising at least the following components: at least one sensing unit, at least control unit, at least one stimulation unit, at least one Central Nervous System (CNS) stimulation module, at least one Peripheral Nervous System (PNS) stimulation module, wherein at least one of the components of the neuromodulation and/or neurostimulation system is implantable.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: August 23, 2022
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Sophie Wurth, Grégoire Courtine, Silvestro Micera
  • Patent number: 11420056
    Abstract: The present invention relates to methods and systems for planning and/or providing neuromodulation. An example system comprises a neurostimulator comprising a least one electrode, functional mapping module configured and arranged such that based on stimulation related basic data and stimulation related response data and transfer data a digital characteristic functional map is generated and/or provided, which describes the interrelation between the stimulation related basic data and the stimulation related response data and the transfer data, and analysis module configured and arranged such that the digital characteristic functional map may be analyzed in connection with neurostimulation provided by the neurostimulator such that the provided neurostimulation and its response may be analyzed on the basis of the functional map and that on the basis of this analysis a placement analysis of a placement of the electrode is provided.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: August 23, 2022
    Assignees: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), ONWARD MEDICAL N.V.
    Inventors: Marco Capogrosso, Karen Minassian, Fabien Wagner, Gregoire Courtine, Miroslav Caban, Robin Brouns, Jurriaan Bakker, Andre Kleibeuker, Bert Bakker, Vincent Delattre
  • Patent number: 11413459
    Abstract: The present invention relates to systems and methods for planning and/or providing neurostimulation for a patient. An example system includes a pathological spinal cord map storage module for storing at least one pathological spinal cord map describing activation of a spinal cord of a patient, a healthy spinal cord map storage module for storing at least one reference map describing physiological activation of the spinal cord of at least one healthy subject, an analysis module for generating a deviation map, the deviation map describing an activation difference between the pathological spinal cord map and the reference map, and a compensation module for calculating, based on the deviation map, a neurostimulation protocol for compensating the activation difference.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: August 16, 2022
    Assignees: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), ONWARD MEDICAL B.V.
    Inventors: Flavio Raschella, Silvestro Misera, Gregoire Courtine, Tomislav Milekovic, Fabien Wagner, Marco Capogrosso, Jurriaan Bakker, Robin Brouns, Vincent Delattre
  • Publication number: 20220184386
    Abstract: A system for neuromodulation and/or neurostimulation, for the treatment of a mammal, at least comprising: at least one control unit configured and arranged to provide stimulation data; at least one stimulation unit configured and arranged to provide a stimulation pulse; at least one real-time monitoring unit; at least one signal-processing unit; wherein the system is configured and arranged for control of blood pressure, wherein the stimulation unit is constructed to comprise a lead, and wherein the lead is capable and configured to provide stimulation to the spinal cord at level T9-L1.
    Type: Application
    Filed: May 14, 2020
    Publication date: June 16, 2022
    Inventors: Gregoire Courtine, Aaron Phillips, Jordan Squair
  • Publication number: 20220143407
    Abstract: A system for providing neuromodulation, especially neurostimulation, comprising a neuromodulator for neuromodulation of a cervical spinal cord, a dorsal neuromodulation array for providing neuromodulation to the cervical spinal cord, a sensor for measuring movements and/or muscle activations of a patient, a mapping module, which is configured and arranged for implementing a mapping between desired muscle activation patterns and neuromodulation parameters, and a processing module which is configured and arranged for processing signals provided by the sensor, further forwarding the processed signals to the mapping module and directing the mapping module output to the neuromodulator.
    Type: Application
    Filed: February 11, 2020
    Publication date: May 12, 2022
    Inventors: Katie ZHUANG, Beatrice BARRA, Elena LOSANNO, Gregoire COURTINE, Marco CAPOGROSSO
  • Publication number: 20220125374
    Abstract: A neuromodulation system, especially a neurostimulation system, for treating a patient, especially for enhancing at least one autonomous function such as blood circulation and/or respiration, wherein the system comprises: at least one signal input module, which is configured to receive at least one or more signals being indicative for blood circulation, especially being indicative for pulse and/or blood pressure, at least one control module, wherein the control module is connected to the signal input module, wherein the control module is configured to adapt the neurostimulation provided by the neuromodulation system on the basis of the signal(s) received by the signal input module.
    Type: Application
    Filed: May 14, 2020
    Publication date: April 28, 2022
    Inventors: Gregoire COURTINE, Aaron PHILLIPS, Jordan SQUAIR, David DARROW
  • Patent number: 11202911
    Abstract: The present invention provides a closed-loop system for real-time control of epidural and/or subdural electrical stimulation comprising: means for applying to a subject neuromodulation with adjustable stimulation parameters, said means being operatively connected with a real-time monitoring component comprising sensors continuously acquiring feedback signals from said subject, said signals being neural signals and/or signals providing features of motion of said subject, said system being operatively connected with a signal processing device receiving said feedback signals and operating real-time automatic control algorithms, said signal processing device being operatively connected with said means and providing said means with new stimulation parameters, with minimum delay. The system of the invention improves consistency of walking in a subject with a neuromotor impairment.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: December 21, 2021
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Gregoire Courtine, Nikolaus Wenger, Eduardo Martin Moraud, Silvestro Micera, Marco Bonizzato
  • Publication number: 20210330962
    Abstract: A neuromodulation system for planning, adjusting, and providing a neuromodulation therapy, comprising: at least one neuromodulation means configured to provide neuromodulation at least partially by means of neurostimulation; at least one neuromodulation controller configured to control the neuromodulation means, wherein the neuromodulation controller is further configured to control the neuromodulation means at the beginning of a neuromodulation action including neurostimulation that the neurostimulation comprises a starting sequence and/or at the end of a neuromodulation action including neurostimulation that the neurostimulation comprises an ending sequence.
    Type: Application
    Filed: April 22, 2021
    Publication date: October 28, 2021
    Applicant: ONWARD MEDICAL B.V.
    Inventors: Miroslav Caban, Joachim von Zitzewitz, Vincent Delattre, Grégoire Courtine, Salif Komi, Robin Demesmaeker, Fabien Wagner
  • Publication number: 20210283001
    Abstract: The present application relates to devices and systems for rehabilitation of the locomotor system, for example limbs. In particular, the present application discloses an apparatus, more in particular a robotic platform capable of optimizing gravity-dependent trunk movements, enabling overground locomotion in non-ambulatory individuals with spinal cord injury and stroke, while promoting durable motor improvement when delivered during gait rehabilitation facilitated by electrical spinal cord stimulation.
    Type: Application
    Filed: August 17, 2017
    Publication date: September 16, 2021
    Inventors: Joachim VON ZITZEWITZ, Jean Baptiste MIGNARDOT, Camille Georgette Marie LE GOFF, Grégoire COURTINE, Heike VALLERY, Michiel Plooij
  • Patent number: 11077009
    Abstract: The present invention relates to a robotic system useful to unload an object/person from its weight. The robotic system is useful in locomotor rehabilitation programs and allows the manipulation of forces in a three-dimensional space with far lower actuator requirements and a much higher precision than prior-art systems. The apparatus combines passive and active elements to minimize actuation requirements while still keeping inertia to a minimum and control precision to a maximum. It requires minimal actuators and at the same time has a low inertia.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: August 3, 2021
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Joachim Von Zitzewitz, Heike Vallery, Gregoire Courtine
  • Publication number: 20210213292
    Abstract: The present invention relates to systems and methods for planning and/or providing neuromodulation One example system includes a stimulation related basic data storage module for storing stimulation related basic data, a stimulation related response data storage module for storing the stimulation related response data, a transfer module configured such that the stimulation related basic data are linked with and/or translated into the response data and/or artificial response data created by the transfer module, wherein the data generated by the transfer module are transfer data, the transfer data comprising link data and/or translation data and/or artificial response data, mapping module configured and arranged such that based on the stimulation related basic data and stimulation related response data and the transfer data a digital characteristic map is generated, and an analysis module configured and arranged such that the digital characteristic map is analyzed automatically.
    Type: Application
    Filed: March 29, 2021
    Publication date: July 15, 2021
    Inventors: Karen MINASSIAN, Fabien WAGNER, Marco CAPOGROSSO, Gregoire COURTINE, Robin BROUNS, Jurriaan BAKKER, Andre KLEIBEUKER, Bert BAKKER, Vincent DELATTRE
  • Publication number: 20210170178
    Abstract: The present invention relates to systems and methods for planning and/or providing neuromodulation. An example system includes a first data input module for stimulation related basic data, a second data input module for stimulation related response data, a transfer module configured and arranged such that the stimulation related basic data received by the data input module are linked and/or translated into and/or with the response data and/or artificial response data created by the transfer module, wherein the data generated by the transfer module are transfer data, the transfer data comprising link data and/or translation data and/or artificial response data, and a mapping module configured and arranged such that based on the stimulation related basic data and stimulation related response data and the transfer data a digital characteristic map is generated, which describes an interrelation between the stimulation related basic data and the stimulation related response data and the transfer data.
    Type: Application
    Filed: November 29, 2018
    Publication date: June 10, 2021
    Inventors: Fabien WAGNER, Karen MINASSIAN, Marco CAPOGROSSO, Gregoire COURTINE, Robin BROUNS, Jurriaan BAKKER, Andre KLEIBEUKER, Bert BAKKER, Vincent DELATTRE
  • Publication number: 20210170177
    Abstract: The present invention relates to systems and methods for planning and/or providing neuromodulation One example system includes a stimulation related basic data storage module for storing stimulation related basic data, a stimulation related response data storage module for storing the stimulation related response data, a transfer module configured such that the stimulation related basic data are linked with and/or translated into the response data and/or artificial response data created by the transfer module, wherein the data generated by the transfer module are transfer data, the transfer data comprising link data and/or translation data and/or artificial response data, mapping module configured and arranged such that based on the stimulation related basic data and stimulation related response data and the transfer data a digital characteristic map is generated, and an analysis module configured and arranged such that the digital characteristic map is analyzed automatically.
    Type: Application
    Filed: November 29, 2018
    Publication date: June 10, 2021
    Inventors: Karen MINASSIAN, Fabien WAGNER, Marco CAPOGROSSO, Gregoire COURTINE, Robin BROUNS, Jurriaan BAKKER, Andre KLEIBEUKER, Bert BAKKER, Vincent DELATTRE