Abstract: Provided is an absorbent material and a method of making an absorbent material. The absorbent material comprises a blend of a super-absorbent first type of gel-forming fiber with a second type of gel-forming fiber, wherein the super-absorbent first type of gel-forming fiber is formed from a super-absorbent polymer. Such absorbent materials are useful in the manufacture of absorbent articles such as wound dressings.

Abstract: An absorbent material for use in wound dressings is provided. The absorbent material comprises a blend of a superabsorbent gel-forming fiber and a non gel-forming fiber, wherein the blend of fiber does not comprise a superabsorbent gel-forming fiber formed from a polysaccharide.

Abstract: A method of producing cellulose fibres impregnated with metal nanoparticles, particularly silver nanoparticles. The method comprises swelling cellulose fibres in an aqueous alkali solution (e.g. NaOH (aq)). The swollen cellulose fibres are removed from the aqueous alkali solution and mixed with an aqueous solution of a metal salt (e.g. AgNO3) and a polymer solution so as to impregnate the fibres with metal nanoparticles. The swollen cellulose fibres impregnated with metal nanoparticles are then removed from the solution. The invention further relates to the composition of cellulose fibres impregnated with metal nanoparticles and an absorbent material (e.g. wound dressing) comprising a blend of cellulose fibres impregnated with metal nanoparticles with at least one other type of fibre.

Abstract: Provided is an absorbent material and a method of making an absorbent material. The absorbent material comprises a blend of a super-absorbent first type of gel-forming fibre with a second type of gel-forming fibre, wherein the super-absorbent first type of gel-forming fibre is formed from a super-absorbent polymer. Such absorbent materials are useful in the manufacture of absorbent articles such as wound dressings.

Abstract: An absorbent material for use in wound dressings is provided. The absorbent material comprises a blend of a superabsorbent gel-forming fibre and a non gel-forming fibre, wherein the blend of fibres does not comprise a superabsorbent gel-forming fibre formed from a polysaccharide.

Abstract: This invention related to a tissue-adhesive sheet comprising a homogeneous, preformed and cross-linked matrix formed from one or more polymers, and having at least one surface that, in use, is exposed, at least one of said one or more polymers being a synthetic polymer and having appendant functional groups of a first form, cross-linking of said matrix being via a proportion of said functional groups of the first form, and the remainder of said functional groups of the first form being free. The sheet is particularly useful as a tissue adhesive and sealant, and is intended for topical application to internal and external surfaces of the body for therapeutic reasons. The invention further relates to sheets comprising a scaffold material, three-dimensional articles formed from similar material to that of the sheet and to implantable medical devices coated with such material.

Abstract: A multi-lamellar tissue-adhesive sheet comprises a structural layer or laminate conjoined to a tissue-contacting layer. The structural layer or laminate comprises one or more synthetic polymers having film-forming properties, and the tissue-contacting layer of material contains tissue-reactive groups. The synthetic polymers having film-forming properties are preferably biodegradable polyesters, and the tissue-reactive groups are most preferably NHS-ester groups.

Abstract: A tissue-adhesive formulation consists of a naturally occurring or synthetic polymerisable and/or cross-linkable material in particulate form, the polymerisable and/or cross-linkable material being in admixture with particulate material comprising tissue-reactive functional groups. The formulation may be used in the preparation of a tissue-adhesive sheet, by applying the formulation to at least one side of a core of a naturally occurring or synthetic polymeric material.

Abstract: A multi-lamellar tissue-adhesive sheet comprises a structural layer or laminate conjoined to a tissue-contacting layer. The structural layer or laminate comprises one or more synthetic polymers having film-forming properties, and the tissue-contacting layer of material contains tissue-reactive groups. The synthetic polymers having film-forming properties are preferably biodegradable polyesters, and the tissue-reactive groups are most preferably NHS-ester groups.

Abstract: A tissue-adhesive formulation comprises a particulate material having tissue-reactive functional groups, in admixture with a particulate buffer material. The formulation is preferably free or substantially free of materials of human or animal origin. In preferred embodiments, the formulation consists, or consists essentially of, an anhydrous or partially hydrated blend of particulate material having tissue-reactive functional groups and particulate buffer material. Also disclosed is a multilayer sheet comprising a structural support coated on at least one side thereof with such a tissue-adhesive formulation.

Abstract: This invention related to a tissue-adhesive sheet comprising a homogeneous, preformed and cross-linked matrix formed from one or more polymers, and having at least one surface that, in use, is exposed, at least one of said one or more polymers being a synthetic polymer and having appendant functional groups of a first form, cross-linking of said matrix being via a proportion of said functional groups of the first form, and the remainder of said functional groups of the first form being free. The sheet is particularly useful as a tissue adhesive and sealant, and is intended for topical application to internal and external surfaces of the body for therapeutic reasons. The invention further relates to sheets comprising a scaffold material, three-dimensional articles formed from similar material to that of the sheet and to implantable medical devices coated with such material.

Abstract: A tissue-adhesive formulation consists of a naturally occurring or synthetic polymerisable and/or cross-linkable material in particulate form, the polymerisable and/or cross-linkable material being in admixture with particulate material comprising tissue-reactive functional groups. The formulation may be used in the preparation of a tissue-adhesive sheet, by applying the formulation to at least one side of a core of a naturally occurring or synthetic polymeric material.