Abstract: This disclosure enables non-invasively obtaining a blood pressure measurement of a person in a repeatable manner in order to provide frequent updates to the blood pressure measurement, while 1) being comfortable for the person when the person is conscious, 2) enabling relaxation of the person, 3) allowing the person to fall asleep, or 4) avoiding waking the person if the person is already asleep. After a first set of blood flow waveform data associated with a blood pressure measurement has been acquired (304), a second set of waveform data is received (306), a parameter change in the second waveform data is identified (308), the parameter change is correlated to the blood pressure measurement (310) so as to generate a virtual blood pressure (312), and an action is taken (314) based on the virtual blood pressure.

Abstract: A system for determining peripheral artery disease and method of use for determining the presence or absence of peripheral vascular disease and the severity of the disease in particular vascular segments. The System for determining peripheral artery disease and method of use includes a continuous wave Doppler transceiver which generates a digitized version of quadrature detected stereo audio and is coupleable to a waveform converter and processor. The waveform converter and processor provides filtering, time domain to frequency domain conversion, gain control, and statistical processing of the converted Doppler Stereo audio and is operationally coupled to a display for presenting results to a technician.

Abstract: Provided are methods related to treating congenital adrenal hyperplasia in a subject in need thereof comprising administering to the subject a compound of Formula (I): [INSERT FORMULA] (I), or a pharmaceutically acceptable salt thereof.

Abstract: A system for determining peripheral artery disease and method of use for determining the presence or absence of peripheral vascular disease and the severity of the disease in particular vascular segments. The System for determining peripheral artery disease and method of use includes a continuous wave Doppler transceiver which generates a digitized version of quadrature detected stereo audio and is coupleable to a waveform converter and processor. The waveform converter and processor provides filtering, time domain to frequency domain conversion, gain control, and statistical processing of the converted Doppler Stereo audio and is operationally coupled to a display for presenting results to a technician.

Abstract: A system for determining peripheral artery disease and method of use for determining the presence or absence of peripheral vascular disease and the severity of the disease in particular vascular segments. The System for determining peripheral artery disease and method of use includes a continuous wave Doppler transceiver which generates a digitized version of quadrature detected stereo audio and is coupleable to a waveform converter and processor. The waveform converter and processor provides filtering, time domain to frequency domain conversion, gain control, and statistical processing of the converted Doppler Stereo audio and is operationally coupled to a display for presenting results to a technician.

Abstract: A system for determining peripheral artery disease and method of use for determining the presence or absence of peripheral vascular disease and the severity of the disease in particular vascular segments. The System for determining peripheral artery disease and method of use includes a continuous wave Doppler transceiver which generates a digitized version of quadrature detected stereo audio and is coupleable to a waveform converter and processor. The waveform converter and processor provides filtering, time domain to frequency domain conversion, gain control, and statistical processing of the converted Doppler Stereo audio and is operationally coupled to a display for presenting results to a technician.

Abstract: Provided are methods related to treating congenital adrenal hyperplasia in a subject in need thereof comprising administering 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine (Formula 1), or a pharmaceutically acceptable salt thereof. Further provided are pharmaceutical formulations and solid forms of 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine, or a pharmaceutically acceptable salt thereof, and their use in the treatment of congenital adrenal hyperplasia (CAH).

Abstract: A reality viewer is disclosed. The reality viewer comprises a frame suitable for holding a portable electronic device and a viewing aperture. The reality viewer can interchange between a first viewing mode wherein the viewing aperture is closed and a second viewing mode wherein the viewing aperture is open. The first viewing mode is configured for virtual reality operation as a user only observes the screen of the electronic portable device located within the frame. By contrast, in the second viewing mode is configured for augmented reality operation as a user observes the real world through the viewing aperture which is augmented by images generated by the electronic portable device located within the frame. The reality viewer also has the advantage of being mobile; low cost; employs simple technology; produces an immersive, maximised field of view; and provides a real-world view in augmented reality mode of operation.

Abstract: A system for determining peripheral artery disease and method of use for determining the presence or absence of peripheral vascular disease and the severity of the disease in particular vascular segments. The System for determining peripheral artery disease and method of use includes a continuous wave Doppler transceiver which generates a digitized version of quadrature detected stereo audio and is coupleable to a waveform converter and processor. The waveform converter and processor provides filtering, time domain to frequency domain conversion, gain control, and statistical processing of the converted Doppler Stereo audio and is operationally coupled to a display for presenting results to a technician.

Abstract: A system for determining peripheral artery disease and method of use for determining the presence or absence of peripheral vascular disease and the severity of the disease in particular vascular segments. The System for determining peripheral artery disease and method of use includes a continuous wave Doppler transceiver which generates a digitized version of quadrature detected stereo audio and is coupleable to a waveform converter and processor. The waveform converter and processor provides filtering, time domain to frequency domain conversion, gain control, and statistical processing of the converted Doppler Stereo audio and is operationally coupled to a display for presenting results to a technician.

Abstract: A reality viewer is disclosed. The reality viewer comprises a frame suitable for holding a portable electronic device and a viewing aperture. The reality viewer can interchange between a first viewing mode wherein the viewing aperture is closed and a second viewing mode wherein the viewing aperture is open. The first viewing mode is configured for virtual reality operation as a user only observes the screen of the electronic portable device located within the frame. By contrast, in the second viewing mode is configured for augmented reality operation as a user observes the real world through the viewing aperture which is augmented by images generated by the electronic portable device located within the frame. The reality viewer also has the advantage of being mobile; low cost; employs simple technology; produces an immersive, maximised field of view; and provides a real-world view in augmented reality mode of operation.

Abstract: An interactive toy is described that provides a physical representation of an avatar created by a user within a virtual or on-line gaming environment. The interactive toy comprises a unique identifier tag and an electrical circuit the electrical circuit comprising, an identifier tag sensor and an interface that provides a means for the toy to communicate with a computer system. The inclusion of the unique identifier tag allows for a portable toy to be produced that can act as both an identifier and a scanner and so provides for increased interaction within the real world for the users of the interactive toys. As a result such toys are able to record physical meetings that can be reflected as befriending events in the corresponding virtual on-line world.

Abstract: An interactive toy is described that provides a physical representation of an avatar created by a user within a virtual or on-line gaming environment. The interactive toy comprises a unique identifier tag and an electrical circuit the electrical circuit comprising, an identifier tag sensor and an interface that provides a means for the toy to communicate with a computer system. The inclusion of the unique identifier tag allows for a portable toy to be produced that can act as both an identifier and a scanner and so provides for increased interaction within the real world for the users of the interactive toys. As a result such toys are able to record physical meetings that can be reflected as befriending events in the corresponding virtual on-line world.

Abstract: A toy snake that reproduces the natural movement of a snake as it moves across surface is described. The toy snake comprises a head that is pivotally mounted to a tail and a motor unit located within the head. In a preferred embodiment a body is employed to pivotally mount the head to the tail. The motor unit comprises at least two independently driven wheels located towards opposite sides of the head and the motor unit is configured to introduce a periodic oscillation between the operation of the independently driven wheels. The motor unit may also be configured to operate a tongue that extends out from the head to further increase the realistic nature of the toy. Embodiments of the snake may be adapted for use on land or water.

Abstract: A toy snake that reproduces the natural movement of a snake as it moves across surface is described. The toy snake comprises a head that is pivotally mounted to a tail and a motor unit located within the head. In a preferred embodiment a body is employed to pivotally mount the head to the tail. The motor unit comprises at least two independently driven wheels located towards opposite sides of the head and the motor unit is configured to introduce a periodic oscillation between the operation of the independently driven wheels. The motor unit may also be configured to operate a tongue that extends out from the head to further increase the realistic nature of the toy. Embodiments of the snake may be adapted for use on land or water.

Abstract: An emulsion for treating natural fabrics is provided which comprises lanolin, water, perfume and is essentially free of cationic surfactant. Also included is an article for treating natural fabrics wherein the article comprises a substrate and an emulsion, a kit for treating natural fabrics, and a method of treating natural fabrics in a dryer.