Patents by Inventor Grahame Mackenzie

Grahame Mackenzie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240139335
    Abstract: An exine-construct that can be coloured and used as a protection and/or delivery and/or removal vehicle for an active substance, or as an antioxidant. It can be used in a method of surgery, therapy, prevention or diagnosis. The invention provides an exine-construct comprising of exine shells together with an active substance; and a method for preparing the exine-construct by isolating exine shells from a naturally occurring spore and suitably attaching them together.
    Type: Application
    Filed: February 25, 2022
    Publication date: May 2, 2024
    Applicant: BOTANICAL SOLUTIONS LIMITED
    Inventors: Grahame MacKenzie, Terence Simon Corbitt, Guy Monroe Entract
  • Publication number: 20240139111
    Abstract: A one-pot procedure to extract a dispersible exine shell. The shell can be used as a protection and/or delivery and/or removal vehicle for active substances or as an antioxidant. The invention provides a formulation containing the dispersible exine shell together with an active substance; and a method for preparing the shell by isolating a dispersible exine shell from a naturally occurring spore or pollen grain by treating the spore or pollen grain with a base or surfactant or both with or without a catalyst in the same reaction vessel.
    Type: Application
    Filed: February 25, 2022
    Publication date: May 2, 2024
    Applicant: SPOROMEX LIMITED
    Inventors: Grahame MacKenzie, Terence Simon Corbitt, Guy Monroe Entract
  • Patent number: 8828464
    Abstract: A whitened exine shell having a degree of whiteness (L*) of greater than 65 measured under D 65 illumination. The shell can be used as a delivery vehicle for an active substance, or as an antioxidant. It can be used in a method of surgery, therapy or diagnosis. The invention provides a formulation containing the whitened exine shell together with an active substance; and a method for preparing the shell by isolating an exine shell from a naturally occurring spore under treatment conditions which do not include aceto lysis, and treating the isolated shell or a precursor thereof with a bleaching composition.
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: September 9, 2014
    Assignee: University of Hull
    Inventors: Stephen Atkin, Stephen Beckett, Grahame Mackenzie
  • Patent number: 8784851
    Abstract: Topical formulation containing an active substance which is chemically or physically bound to, or encapsulated within, an exine shell of a naturally occurring spore. The active substance can be released from the exine shell on application to a living or non-living surface. The invention may be used to provide gradual release of an active substance over a period of time subsequent to application of the formulation to the surface.
    Type: Grant
    Filed: July 27, 2006
    Date of Patent: July 22, 2014
    Assignee: University of Hull
    Inventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
  • Publication number: 20130309298
    Abstract: A formulation containing an active substance encapsulated within an exine shell of a naturally occurring spore, together with a protective additive which is also encapsulated within the exine shell.
    Type: Application
    Filed: June 26, 2013
    Publication date: November 21, 2013
    Inventors: Stephen Lawrence ATKIN, Stephen Thomas BECKETT, Alberto DIEGO-TABOADA, Grahame MACKENZIE
  • Publication number: 20110117148
    Abstract: A whitened exine shell having a degree of whiteness (L*) of greater than 65 measured under D 65 illumination. The shell can be used as a delivery vehicle for an active substance, or as an antioxidant. It can be used in a method of surgery, therapy or diagnosis. The invention provides a formulation containing the whitened exine shell together with an active substance; and a method for preparing the shell by isolating an exine shell from a naturally occurring spore under treatment conditions which do not include acetolysis, and treating the isolated shell or a precursor thereof with a bleaching composition.
    Type: Application
    Filed: July 9, 2009
    Publication date: May 19, 2011
    Inventors: Stephen Atkin, Stephen Beckett, Grahame Mackenzie
  • Publication number: 20110002984
    Abstract: A formulation containing an active substance encapsulated within an exine shell of a naturally occurring spore, together with a protective additive which is also encapsulated within the exine shell.
    Type: Application
    Filed: December 17, 2008
    Publication date: January 6, 2011
    Applicant: UNIVERSITY OF HULL
    Inventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Alberto Diego-Taboada, Grahame MacKenzie
  • Patent number: 7846654
    Abstract: This invention provides the use of an exine shell of a naturally occurring spore, or a fragment thereof, as an antioxidant, for instance in a composition or formulation containing an active substance. Also provided is a method for reducing rancidity, or other oxidative degradation, of a substance, composition, or formulation, by encapsulating the substance, composition, or formulation in, or chemically binding it to, or mixing it with, an exine shell of a naturally occurring spore or a fragment thereof.
    Type: Grant
    Filed: January 25, 2008
    Date of Patent: December 7, 2010
    Assignee: University of Hull
    Inventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
  • Patent number: 7608270
    Abstract: A pharmaceutical or dietetic dosage form comprising of effective quantity of an active substance chemically or physically bound to a support comprising sporopollenin, or other similar exine coating of spores, of a plant or fungus, optionally with further excipients.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: October 27, 2009
    Assignee: University of Hull
    Inventors: Stephen Thomas Beckett, Stephen Lawrence Atkin, Grahame Mackenzie
  • Publication number: 20090246125
    Abstract: An image enhancing agent of a form comprising an effective quantity of an image enhancing material chemically or physically bound to or encapsulated within a support comprising, preferentially, an exine coating of spores of various plants or fungi, optionally with further excipients.
    Type: Application
    Filed: December 14, 2005
    Publication date: October 1, 2009
    Inventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
  • Publication number: 20080311213
    Abstract: Topical formulation containing an active substance which is chemically or physically bound to, or encapsulated within, an exine shell of a naturally occurring spore. The active substance can be released from the exine shell on application to a living or non-living surface. The invention may be used to provide gradual release of the active substance over a period of time subsequent to application of the formulation to the surface.
    Type: Application
    Filed: July 27, 2006
    Publication date: December 18, 2008
    Inventors: Stephen Lawrence Atkin, Stephen Thomas Backett, Grahame MacKenzie
  • Publication number: 20080188572
    Abstract: This invention provides the use of an exine shell of a naturally occurring spore, or a fragment thereof, as an antioxidant, for instance in a composition or formulation containing an active substance. Also provided is a method for reducing rancidity, or other oxidative degradation, of a substance, composition, or formulation, by encapsulating the substance, composition, or formulation in, or chemically binding it to, or mixing it with, an exine shell of a naturally occurring spore or a fragment thereof.
    Type: Application
    Filed: January 25, 2008
    Publication date: August 7, 2008
    Applicant: UNIVERSITY OF HULL
    Inventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
  • Publication number: 20050002963
    Abstract: A pharmaceutical or dietetic dosage form comprising of effective quantity of an active substance chemically or physically bound to a support comprising sporopollenin, or other similar exine coating of spores, of a plant or fungus, optionally with further excipients.
    Type: Application
    Filed: June 25, 2004
    Publication date: January 6, 2005
    Inventors: Stephen Beckett, Stephen Atkin, Grahame Mackenzie