Patents by Inventor Grahame Mackenzie
Grahame Mackenzie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240139335Abstract: An exine-construct that can be coloured and used as a protection and/or delivery and/or removal vehicle for an active substance, or as an antioxidant. It can be used in a method of surgery, therapy, prevention or diagnosis. The invention provides an exine-construct comprising of exine shells together with an active substance; and a method for preparing the exine-construct by isolating exine shells from a naturally occurring spore and suitably attaching them together.Type: ApplicationFiled: February 25, 2022Publication date: May 2, 2024Applicant: BOTANICAL SOLUTIONS LIMITEDInventors: Grahame MacKenzie, Terence Simon Corbitt, Guy Monroe Entract
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Publication number: 20240139111Abstract: A one-pot procedure to extract a dispersible exine shell. The shell can be used as a protection and/or delivery and/or removal vehicle for active substances or as an antioxidant. The invention provides a formulation containing the dispersible exine shell together with an active substance; and a method for preparing the shell by isolating a dispersible exine shell from a naturally occurring spore or pollen grain by treating the spore or pollen grain with a base or surfactant or both with or without a catalyst in the same reaction vessel.Type: ApplicationFiled: February 25, 2022Publication date: May 2, 2024Applicant: SPOROMEX LIMITEDInventors: Grahame MacKenzie, Terence Simon Corbitt, Guy Monroe Entract
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Patent number: 8828464Abstract: A whitened exine shell having a degree of whiteness (L*) of greater than 65 measured under D 65 illumination. The shell can be used as a delivery vehicle for an active substance, or as an antioxidant. It can be used in a method of surgery, therapy or diagnosis. The invention provides a formulation containing the whitened exine shell together with an active substance; and a method for preparing the shell by isolating an exine shell from a naturally occurring spore under treatment conditions which do not include aceto lysis, and treating the isolated shell or a precursor thereof with a bleaching composition.Type: GrantFiled: July 9, 2009Date of Patent: September 9, 2014Assignee: University of HullInventors: Stephen Atkin, Stephen Beckett, Grahame Mackenzie
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Patent number: 8784851Abstract: Topical formulation containing an active substance which is chemically or physically bound to, or encapsulated within, an exine shell of a naturally occurring spore. The active substance can be released from the exine shell on application to a living or non-living surface. The invention may be used to provide gradual release of an active substance over a period of time subsequent to application of the formulation to the surface.Type: GrantFiled: July 27, 2006Date of Patent: July 22, 2014Assignee: University of HullInventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
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Publication number: 20130309298Abstract: A formulation containing an active substance encapsulated within an exine shell of a naturally occurring spore, together with a protective additive which is also encapsulated within the exine shell.Type: ApplicationFiled: June 26, 2013Publication date: November 21, 2013Inventors: Stephen Lawrence ATKIN, Stephen Thomas BECKETT, Alberto DIEGO-TABOADA, Grahame MACKENZIE
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Publication number: 20110117148Abstract: A whitened exine shell having a degree of whiteness (L*) of greater than 65 measured under D 65 illumination. The shell can be used as a delivery vehicle for an active substance, or as an antioxidant. It can be used in a method of surgery, therapy or diagnosis. The invention provides a formulation containing the whitened exine shell together with an active substance; and a method for preparing the shell by isolating an exine shell from a naturally occurring spore under treatment conditions which do not include acetolysis, and treating the isolated shell or a precursor thereof with a bleaching composition.Type: ApplicationFiled: July 9, 2009Publication date: May 19, 2011Inventors: Stephen Atkin, Stephen Beckett, Grahame Mackenzie
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Publication number: 20110002984Abstract: A formulation containing an active substance encapsulated within an exine shell of a naturally occurring spore, together with a protective additive which is also encapsulated within the exine shell.Type: ApplicationFiled: December 17, 2008Publication date: January 6, 2011Applicant: UNIVERSITY OF HULLInventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Alberto Diego-Taboada, Grahame MacKenzie
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Patent number: 7846654Abstract: This invention provides the use of an exine shell of a naturally occurring spore, or a fragment thereof, as an antioxidant, for instance in a composition or formulation containing an active substance. Also provided is a method for reducing rancidity, or other oxidative degradation, of a substance, composition, or formulation, by encapsulating the substance, composition, or formulation in, or chemically binding it to, or mixing it with, an exine shell of a naturally occurring spore or a fragment thereof.Type: GrantFiled: January 25, 2008Date of Patent: December 7, 2010Assignee: University of HullInventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
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Patent number: 7608270Abstract: A pharmaceutical or dietetic dosage form comprising of effective quantity of an active substance chemically or physically bound to a support comprising sporopollenin, or other similar exine coating of spores, of a plant or fungus, optionally with further excipients.Type: GrantFiled: June 25, 2004Date of Patent: October 27, 2009Assignee: University of HullInventors: Stephen Thomas Beckett, Stephen Lawrence Atkin, Grahame Mackenzie
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Publication number: 20090246125Abstract: An image enhancing agent of a form comprising an effective quantity of an image enhancing material chemically or physically bound to or encapsulated within a support comprising, preferentially, an exine coating of spores of various plants or fungi, optionally with further excipients.Type: ApplicationFiled: December 14, 2005Publication date: October 1, 2009Inventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
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Publication number: 20080311213Abstract: Topical formulation containing an active substance which is chemically or physically bound to, or encapsulated within, an exine shell of a naturally occurring spore. The active substance can be released from the exine shell on application to a living or non-living surface. The invention may be used to provide gradual release of the active substance over a period of time subsequent to application of the formulation to the surface.Type: ApplicationFiled: July 27, 2006Publication date: December 18, 2008Inventors: Stephen Lawrence Atkin, Stephen Thomas Backett, Grahame MacKenzie
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Publication number: 20080188572Abstract: This invention provides the use of an exine shell of a naturally occurring spore, or a fragment thereof, as an antioxidant, for instance in a composition or formulation containing an active substance. Also provided is a method for reducing rancidity, or other oxidative degradation, of a substance, composition, or formulation, by encapsulating the substance, composition, or formulation in, or chemically binding it to, or mixing it with, an exine shell of a naturally occurring spore or a fragment thereof.Type: ApplicationFiled: January 25, 2008Publication date: August 7, 2008Applicant: UNIVERSITY OF HULLInventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
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Publication number: 20050002963Abstract: A pharmaceutical or dietetic dosage form comprising of effective quantity of an active substance chemically or physically bound to a support comprising sporopollenin, or other similar exine coating of spores, of a plant or fungus, optionally with further excipients.Type: ApplicationFiled: June 25, 2004Publication date: January 6, 2005Inventors: Stephen Beckett, Stephen Atkin, Grahame Mackenzie