Patents by Inventor Grant Hogg

Grant Hogg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes and Compositions for Methylation-Based Enrichment of Fetal Nucleic Acid From a Maternal Sample Useful for Non-Invasive Prenatal Diagnoses
    Publication number: 20230060700
    Abstract: Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuploidies.
    Type: Application
    Filed: April 22, 2022
    Publication date: March 2, 2023
    Applicant: Sequenom, Inc.
    Inventors: John Allen Tynan, Grant Hogg
  • Methods and processes for non-invasive assessment of genetic variations
    Patent number: 11492659
    Abstract: Provided herein are methods for determining fetal ploidy according to nucleic acid sequence reads. Nucleic acid sequence reads may be obtained from test sample nucleic acid comprising circulating cell-free nucleic acid from the blood of a pregnant female bearing a fetus. Fetal ploidy may be determined according to genomic section levels and a fraction of fetal nucleic acid in a test sample.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: November 8, 2022
    Assignee: Sequenom, Inc.
    Inventors: Cosmin Deciu, Zeljko Dzakula, John Allen Tynan, Grant Hogg
  • Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
    Patent number: 11332791
    Abstract: Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuploidies.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: May 17, 2022
    Assignee: Sequenom, Inc.
    Inventors: John Allen Tynan, Grant Hogg
  • Methods and Processes for Non-Invasive Assessment of Genetic Variations
    Publication number: 20190276874
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Application
    Filed: December 10, 2018
    Publication date: September 12, 2019
    Inventors: Cosmin Deciu, Zeljko Dzakula, John Allen Tynan, Grant Hogg
  • Methods and processes for non-invasive assessment of genetic variations
    Patent number: 10196681
    Abstract: Provided herein are methods, processes and apparatuses for determining the fraction of fetal nucleic acid in a test sample derived from a pregnant female with improved accuracy and/or precision. Also, provided herein are methods, processes and apparatuses for determining the presence or absence of a genetic variation in a fetus with improved accuracy and/or precision. Certain methods include using fetal fraction measurements for the determination of a fetal genetic variation.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: February 5, 2019
    Assignee: Sequenom, Inc.
    Inventors: Cosmin Deciu, Zeljko Dzakula, John Allen Tynan, Grant Hogg
  • PROCESSES AND COMPOSITIONS FOR METHYLATION-BASED ENRICHMENT OF FETAL NUCLEIC ACID FROM A MATERNAL SAMPLE USEFUL FOR NON-INVASIVE PRENATAL DIAGNOSES
    Publication number: 20170058350
    Abstract: Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuploidies.
    Type: Application
    Filed: September 9, 2016
    Publication date: March 2, 2017
    Inventors: John Allen TYNAN, Grant HOGG
  • PROCESSES AND COMPOSITIONS FOR METHYLATION-BASED ENRICHMENT OF FETAL NUCLEIC ACID FROM A MATERNAL SAMPLE USEFUL FOR NON-INVASIVE PRENATAL DIAGNOSES
    Publication number: 20140093873
    Abstract: Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuploidies.
    Type: Application
    Filed: July 11, 2013
    Publication date: April 3, 2014
    Applicant: SEQUENOM, INC.
    Inventors: John Allen TYNAN, Grant Hogg
  • METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS
    Publication number: 20130288244
    Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
    Type: Application
    Filed: March 14, 2013
    Publication date: October 31, 2013
    Inventors: Cosmin DECIU, Zeljko Dzakula, John Allen Tynan, Grant Hogg