Patents by Inventor Grant Zimmermann

Grant Zimmermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATIONS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS
    Publication number: 20110223621
    Abstract: The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.
    Type: Application
    Filed: March 15, 2011
    Publication date: September 15, 2011
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole W. Hurst, Michael A. Foley
  • Combinations for the treatment of immunoinflammatory disorders
    Patent number: 7915265
    Abstract: The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: March 29, 2011
    Assignee: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole W. Hurst, Michael A. Foley
  • COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20080280863
    Abstract: The invention features methods and compositions for the treatment of immunoinflammatory disorders.
    Type: Application
    Filed: February 25, 2008
    Publication date: November 13, 2008
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Combinations for the treatment of inflammatory disorders
    Patent number: 7335371
    Abstract: The invention features methods and compositions for the treatment of immunonflammatory disorders.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: February 26, 2008
    Assignee: CombinatoRx, Incorporated
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Combinations for the treatment of rheumatoid arthritis
    Publication number: 20070259841
    Abstract: The invention features a method for treating a patient diagnosed with rheumatoid arthritis by systemically administering an azole and a steroid to the patient. The invention also features a pharmaceutical composition containing an azole and a steroid for the treatment of rheumatoid arthritis.
    Type: Application
    Filed: June 13, 2007
    Publication date: November 8, 2007
    Applicant: CombinatoRx, Incorporated
    Inventors: Jason Fong, Edward Jost-Price, Curtis Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Grant Zimmermann
  • Combination therapy for the treatment of neoplasms
    Publication number: 20070179152
    Abstract: The invention features compositions, methods, and kits for the treatment of neoplasms
    Type: Application
    Filed: May 21, 2004
    Publication date: August 2, 2007
    Inventors: Margaret Lee, M. Nichols, Amy Wilson, Grant Zimmermann
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Publication number: 20070010502
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 11, 2007
    Applicant: CombinatoRx Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley, Michael Slavonic, Brendan Smith, Benjamin Auspitz
  • Methods and reagents for the treatment of inflammatory disorders
    Publication number: 20060286177
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering bufexamac and a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing bufexamac and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: June 16, 2006
    Publication date: December 21, 2006
    Applicant: CombinatoRx, Inc.
    Inventors: Edward Jost-Price, Garry Nolan, Grant Zimmermann
  • Compositions and methods for treatment for neoplasms
    Publication number: 20060264384
    Abstract: The invention features compositions including two, three, or more agents useful in treating a patient with a neoplasm, methods for treatment of a patient with a neoplasm such as cancer (e.g., brain cancer), kits which include one, two, three, or more agents useful in the treatment of cancer, as well as methods for identifying combinations of compounds potentially useful in treating a patient with a neoplasm.
    Type: Application
    Filed: May 4, 2006
    Publication date: November 23, 2006
    Inventors: Lisa Johansen, Margaret Lee, M. Nichols, Grant Zimmermann
  • Combination therapy for the treatment of neoplasms
    Publication number: 20060241122
    Abstract: The invention features compositions, methods, and kits for the treatment of neoplasms.
    Type: Application
    Filed: May 27, 2004
    Publication date: October 26, 2006
    Inventors: Margaret Lee, M. Nichols, Amy Beth Wilson, Grant Zimmermann
  • Combinations for the treatment of immunoinflammatory disorders
    Publication number: 20060234991
    Abstract: The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.
    Type: Application
    Filed: February 15, 2006
    Publication date: October 19, 2006
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley
  • Combinations for the treatment of rheumatoid arithritis
    Publication number: 20060148770
    Abstract: The invention features a method for treating a patient diagnosed with rheumatoid arthitis by systemically administering an azole and a steroid to the patient. The invention also features a pharmaceutical composition containing an azole and a steroid for the treatment of rheumatoid arthritis.
    Type: Application
    Filed: June 5, 2003
    Publication date: July 6, 2006
    Inventors: Jason Fong, Edward Jost-Price, Curtis Keith, Palaniyandi Manivasakam, Grant Zimmermann, Robyn Sackeyfio, Grant Zimmermann
  • Combinations for the treatment of inflammatory skin disorders
    Publication number: 20060100181
    Abstract: The invention features methods and compositions for the treatment of inflammatory skin conditions.
    Type: Application
    Filed: May 2, 2003
    Publication date: May 11, 2006
    Inventors: Edward Jost-Price, Palaniyandi Manivasakam, Grant Zimmermann, Jason Fong, Nicole Hurst, Benjamin Auspitz, M Nichols, Curtis Keith
  • Methods and reagents for the treatment of metabolic disorders
    Publication number: 20060069161
    Abstract: The invention features compositions, methods, and kits for the treatment of metabolic disorders such as diabetes and obesity.
    Type: Application
    Filed: June 30, 2005
    Publication date: March 30, 2006
    Applicant: CombinatoRx, Inc.
    Inventors: Margaret Lee, Grant Zimmermann, Alyce Finelli, Daniel Grau, Curtis Keith, M. Nichols
  • Combinations for the treatment of inflammatory disorders
    Patent number: 6955815
    Abstract: The invention features a pharmaceutical composition that includes amoxapine and a corticosteroid.
    Type: Grant
    Filed: September 29, 2003
    Date of Patent: October 18, 2005
    Assignee: CombinatoRx, Incorporated
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Methods and reagents for the treatment of inflammatory disorders
    Publication number: 20050187200
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: November 12, 2004
    Publication date: August 25, 2005
    Inventors: Benjamin Auspitz, Alexis Borisy, Jason Fong, Nicole Hurst, Edward Jost-Price, Curtis Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Michael Slavonic, Brendan Smith, Grant Zimmermann
  • Combinations for the treatment of immunoinflammatory disorders and proliferative skin diseases
    Publication number: 20050159485
    Abstract: The invention features a method for treating a patient who has an immunoinflammatory disorder or a proliferative skin disease, or is at risk for developing an immunoinflammatory disorder or a proliferative skin disease, by administering to the patient a prostaglandin and a retinoid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammatory or dermal/epidermal proliferation.
    Type: Application
    Filed: January 2, 2003
    Publication date: July 21, 2005
    Inventors: Edward Jost-Price, Palaniyandi Manivasakam, Grant Zimmermann, Nicole Hurst, Jason Fong, Curtis Keith, Alexis Borisy
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Publication number: 20050119160
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: October 15, 2004
    Publication date: June 2, 2005
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley, Michael Slavonic, Brendan Smith, Benjamin Auspitz
  • Combinations for the treatment of inflammatory disorders
    Patent number: 6897206
    Abstract: The invention features a method for treating a patient having an inflammatory disorder, by administering to the patient (i) a tricyclic antidepressant (e.g., amoxapine); and (ii) a corticosteroid (e.g., prednisolone) simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit inflammation.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: May 24, 2005
    Assignee: CombinatoRx, Inc.
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Using multiple perturbations to elucidate connectivity in network systems
    Publication number: 20050090992
    Abstract: One embodiment of the invention is a method of analyzing the effects of combined perturbers of a network system by means of a set of model predictions for various network configurations, using a set of phenomenologically-based combination surface models. This method can be used to predict the effects of combined perturbers of known networks, for example, providing mechanistic validation for therapeutic compounds. Alternatively, this method can provide constraints for constructing connectivity models from observed combination effects on networks of unknown structure, thus, for example, providing the required understanding to identify novel targets for therapeutic compounds.
    Type: Application
    Filed: September 27, 2004
    Publication date: April 28, 2005
    Inventors: Joseph Lehar, Raymond Molnar, Curtis Keith, Grant Zimmermann