Abstract: An electrified vehicle includes a storage compartment positioned forward of a vehicle passenger cabin and accessible by opening a vehicle hood, a thermally conductive plate or heat exchanger in contact with a bottom surface of the storage compartment and having an associated conduit configured for circulating a working fluid from a vehicle cooling system, and a valve operable to control flow of the working fluid through the conduit. The storage compartment may be filled with a cooling medium, such as ice or dry ice, to provide enhanced cooling during high-demand operation or charging of the vehicle, such as when operating in a performance/track mode, towing a trailer, or in other extreme use scenarios. The valve may be controlled so that the working fluid bypasses the conduit when the storage compartment is used for cargo and/or enhanced cooling is not desired.

Abstract: Certain embodiments are directed to methods of treating or preventing an addictive behavior in a subject by administering to the subject an effective amount of a 5-HT2C receptor agonist in combination with a DA D3/D4 receptor antagonist.

Abstract: A method and apparatus are provided for a hemodiafiltration delivery module that is used in conjunction with a UF controlled dialysis machine to enable hemodiafiltration therapy to be performed. The advantage is that one can fully utilize a current functioning dialysis machine to perform a hemodiafiltration therapy as opposed to purchasing a completely new machine that offers this capability.

Abstract: Certain embodiments are directed to methods of treating or preventing an addictive behavior in a subject by administering to the subject an effective amount of a 5-HT2C receptor agonist in combination with a DA D3/D4 receptor antagonist.

Abstract: A compressed air system is provided for automotive or motorcycle use, wherein compressed air is utilized to assist clearing a windshield or a windscreen during foul weather. The system comprises an electrically driven or belt driven air compressor, a compressed air reservoir tank, a network of air lines throughout the vehicle or attached to a rider's helmet, and a plurality of air nozzles that release the air from the air lines on command. The ejected air is highly pressurized and exits at a high velocity to remove water droplets and particles for improved clarity through the windshield or wind screen. A user-operated switch controls at least one valve to release the compressed air from the network of air lines and through the nozzles, wherein the compressed air tank is continually replenished to allow for consistent and repeated bursts of compressed air over an extended period.

Abstract: A flushable filter system is configured to purify a contaminated liquid containing substances that degrade filter performance and includes a filter cartridge including semi-permeable hollow fiber membrane that separates the filter cartridge into an upstream compartment and a downstream compartment. The system includes a flush port in communication with the upstream compartment of the filter cartridge for periodically discharging accumulated particulates and contaminates from an upstream side of the semi-permeable hollow fiber membrane. A device is provided to reduce mechanical stress imposed on the semi-permeable hollow fiber membrane during operation of the flushable filter system resulting in maintenance of integrity of the semi-permeable hollow fiber membrane during extended use and cyclic operation of the filter cartridge. The device is configured to dampen any fluid pressure spike that is observed within the flushable filter system during operation thereof.

Abstract: A property management system is disclosed herein. The property management system can include multiple components that operate therein, including a central management system, building management system, inspection management system, and a service management system. Using the property management system, an owner, other authorized representative, manager, tenant, building manager, inspector company and service company may efficiently communicate with each other, and upload reports and status updates directly to the respective systems. Each party may have authorization credentials to access information in the database that is commensurate with their authorization level. The systems and methods disclosed herein provide a convenient platform for the accumulation of data that can include data associated with real property, fixtures, chattel, etc.

Abstract: A flush pump feature on a liquid purifying filter includes a segment of flexible tubing containing a small bulb pump is described. Two check valves are positioned upstream and downstream of the bulb pump which then terminates with a simple manually operated open/closed valve. The addition of this flush pump feature enables the filter unit to be easily purged of air at first use and also will make the filter easier to clean and maintain without the need to remove it from a hydration carrier. In addition, the flush bulb feature can also be used to perform a simple visual integrity test of filter while out in a remote location and also can be used to effectively remove bulk water from the filter for lighter storage when not in use which also minimizes freeze related damage when used in a cold environment.

Abstract: A flush pump feature on a liquid purifying filter includes a segment of flexible tubing containing a small bulb pump is described. Two check valves are positioned upstream and downstream of the bulb pump which then terminates with a simple manually operated open/closed valve. The addition of this flush pump feature enables the filter unit to be easily purged of air at first use and also will make the filter easier to clean and maintain without the need to remove it from a hydration carrier. In addition, the flush bulb feature can also be used to perform a simple visual integrity test of filter while out in a remote location and also can be used to effectively remove bulk water from the filter for lighter storage when not in use which also minimizes freeze related damage when used in a cold environment.

Abstract: A flush pump feature on a liquid purifying filter includes a segment of flexible tubing containing a small bulb pump is described. Two check valves are positioned upstream and downstream of the bulb pump which then terminates with a simple manually operated open/closed valve. The addition of this flush pump feature enables the filter unit to be easily purged of air at first use and also will make the filter easier to clean and maintain without the need to remove it from a hydration carrier. In addition, the flush bulb feature can also be used to perform a simple visual integrity test of filter while out in a remote location and also can be used to effectively remove bulk water from the filter for lighter storage when not in use which also minimizes freeze related damage when used in a cold environment.

Abstract: A compressed air system is provided for automotive or motorcycle use, wherein compressed air is utilized to assist clearing a windshield or a windscreen during foul weather. The system comprises an electrically driven or belt driven air compressor, a compressed air reservoir tank, a network of air lines throughout the vehicle or attached to a rider's helmet, and a plurality of air nozzles that release the air from the air lines on command. The ejected air is highly pressurized and exits at a high velocity to remove water droplets and particles for improved clarity through the windshield or wind screen. A user-operated switch controls at least one valve to release the compressed air from the network of air lines and through the nozzles, wherein the compressed air tank is continually replenished to allow for consistent and repeated bursts of compressed air over an extended period.

Abstract: Potent and selective ligands for the dopamine 3 (D3) receptor are disclosed. The D3 receptor ligands have a structural formula: wherein R1 is C1-6 alkyl or C3-6cycloalkyl; or wherein R2 is substituted with one or two halogen(s) or OC1-3alkyl.

Abstract: The present invention relates to trans-capsularly administering into a diseased joint a high specificity antagonist selected from the group consisting of: i) an inhibitor of a pro-inflammatory interleukin; ii) an inhibitor of TNF-? synthesis; iii) an inhibitor of membrane-bound TNF-?; iv) an inhibitor of a natural receptor of TNF-?; v) an inhibitor of NO synthase, vi) an inhibitor of PLA2 enzyme; vii) an anti-proliferative agent; viii) an anti-oxidant; ix) an apoptosis inhibitor selected from the group consisting of EPO mimetic peptides, EPO mimetibodies, IGF-I, IGF-II, and caspase inhibitors, and x) an inhibitor of MMPs; and xi) an inhibitor of p38 kinase.

Abstract: Potent and selective ligands for the dopamine 3 (D3) receptor are disclosed. The D3 receptor ligands have a structural formula (I) wherein X is C?O or SO2, R1 is C1-6 alkyl, R2 is aryl, heteroaryl, aryl, —(CH2)1-3aryl, or —(CH2)1-3heteroaryl, and n is 0 or 1. Methods of using the D3 receptor ligands in the treatment of diseases and conditions wherein modulation of the D3 receptor provides a benefit also are disclosed.

Abstract: Potent and selective ligands for the dopamine 3 (D3) receptor are disclosed. The D3 receptor ligands have a structural formula: wherein R1 is C1-6 alkyl or C3-6cycloalkyl; or wherein R2 is substituted with one or two halogen(s) or OC1-3alkyl.

Abstract: A back and body stimulator provides a variety of stimulation to body surfaces. The stimulator may comprise a frame that supports one or more stimulating elements. The frame may be held between two handles by one or more resilient or stretchable members. The stimulating elements may engage and be applied to a body surface via the handles. The user may stretch the resilient members to apply a force to the body surface. Stimulation may be provided by moving the stimulating elements across the body surface. The stimulating members may be mounted so as to rotate about distinct axis, to rotate irregularly, or both so that distinct sensations may be generated. The stimulator may include one or more vibration generators or vibrating elements.

Abstract: The present invention relates to administering a doxycycline compound into a diseased intervertebral disc.

Abstract: Potent and selective ligands for the dopamine 3 (D3) receptor are disclosed. The D3 receptor ligands have a structural formula (I) wherein X is C?O or SO2, R1 is C1-6 alkyl, R2 is aryl, heteroaryl, aryl, —(CH2)1-3aryl, or —(CH2)1-3heteroaryl, and n is 0 or 1. Methods of using the D3 receptor ligands in the treatment of diseases and conditions wherein modulation of the D3 receptor provides a benefit also are disclosed.

Abstract: A collapsible bag for carrying articles that includes a folding seat mounted on an exterior surface of the bag. The bag includes side frame members and a bottom plate that are individually pivotable relative to a base frame assembly to change the volume of the interior compartment of the bag. The bag is provided with various article retainers on its exterior surface to provide easy access to articles retained therein.