Patents by Inventor Gregory Cooksey Rigdon

Gregory Cooksey Rigdon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING AGE-RELATED DISEASES AND PREMATURE AGING DISORDERS
    Publication number: 20230136792
    Abstract: The present invention relates to methods of treating, delaying the onset of, slowing the progression of, or reducing the severity of age-related diseases by administering a compound of Formula 1 to a subject in need thereof. The invention further relates to methods of treating, delaying the onset of, slowing the progression of, or reducing the severity of premature aging disorders by administering a compound of Formula 1 to a subject in need thereof.
    Type: Application
    Filed: April 1, 2021
    Publication date: May 4, 2023
    Inventors: Michael Friedrich Ackermann, Kelly J. Abernathy, Gregory Cooksey Rigdon, Stephen E. Butts
  • Methods for treating or preventing pain and anxiety
    Publication number: 20020013349
    Abstract: The present invention relates to a novel method of treating of pain or anxiety, using compounds that modulate KCNQ potassium channels and currents.
    Type: Application
    Filed: August 24, 2001
    Publication date: January 31, 2002
    Inventors: Alan David Wickenden, Gregory Cooksey Rigdon, Grant Andrew McNaughton-Smith, Michael Francis Gross
  • Methods for treating or preventing pain
    Patent number: 6326385
    Abstract: The present invention relates to a novel method of treating of pain, using compounds that modulate KCNQ potassium channels and currents.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: December 4, 2001
    Assignee: ICAgen, Inc.
    Inventors: Alan David Wickenden, Gregory Cooksey Rigdon, Grant Andrew McNaughton-Smith, Michael Francis Gross
  • Gardos channel antagonists
    Patent number: 6288122
    Abstract: Novel inhibitors of potassium flux are disclosed. The inhibitors show surprising resistance to degradation in biological media and enhanced in vivo half-lives relative to non-fluorine substituted homologues. Methods for the use of these compounds include treating sickle cell disease, preventing erythrocyte dehydration and inhibiting potassium flux.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: September 11, 2001
    Assignee: Icagen, Inc.
    Inventors: Grant Andrew McNaughton-Smith, Gregory Cooksey Rigdon, Jonathan Walter Stocker
  • Bicyclic amide derivatives and their use as muscle relaxants
    Patent number: 6124284
    Abstract: Novel compounds of formula (1) together with their salts and solvates have a number of uses in medicine, in particular as central muscle relaxants.
    Type: Grant
    Filed: July 16, 1998
    Date of Patent: September 26, 2000
    Assignee: Glaxo Wellcome Inc.
    Inventors: James Leroy Kelley, Gregory Cooksey Rigdon, Barrett Randolph Cooper, Ed Williams McLean, David Lee Musso, Gloria Faye Orr, Jeffrey Leaman Selph, Virgil Lee Styles
  • Bicyclic amide derivatives and their use as muscle relaxants
    Patent number: 5872118
    Abstract: Novel compounds of formula (I) ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each selected from hydrogen and fluoro and at least one and not more than two is fluoro;R.sup.5 is selected from hydrogen and C.sub.1 -C.sub.4 alkyl;R.sup.6 is selected from hydrogen, C.sub.1 -C.sub.4 ally and hydroxy; orR.sup.5 and R.sup.6 together with the ring carbon form a carbonyl group;R.sup.7 is selected from hydrogen and hydroxy,R.sup.8 and R.sup.9 are each selected from hydrogen, C.sub.1 -C.sub.4 alkyl and cyclo(C.sub.3 or C.sub.4) alkyl or together with the nitrogen form a morpholino group; andX is selected from a bond, methylene and --O-- and is always a bond or --O-- when any of R.sup.5, R.sup.6 and R.sup.7 is other than hydrogen and is always a bond when R.sup.5 and R.sup.6 together with the ring carbon form a carbonyl group;and their salts and solvates have a number of uses as central muscle relaxants. In particular, treatment of conditions associated with abnormally raised skeletal muscle tone.
    Type: Grant
    Filed: December 18, 1995
    Date of Patent: February 16, 1999
    Assignee: Glaxo Wellcome Inc.
    Inventors: James Leroy Kelley, Gregory Cooksey Rigdon, Barrett Randolph Cooper, Ed Williams McLean, David Lee Musso, Gloria Faye Orr, Jeffrey Leaman Selph, Virgil Lee Styles