Abstract: A method and apparatus for treating a body tissue in situ (e.g., an atrial tissue of a heart to treat atrial fibrillation) include a lesion formation tool is positioned against the heart surface. The apparatus includes a guide member having a tissue-opposing surface for placement against a heart surface. The guide member also has interior surfaces and a longitudinal axis. A guide carriage is sized to be received with the guide member and moveable therein along the longitudinal axis. An optical fiber is positioned within the guide carriage with the carriage retaining the fiber. The carriage receives the fiber with an axis substantially parallel to the longitudinal axis and bends the fiber to a distal tip with an axis of said fiber at said distal tip at least 45 degrees to the longitudinal axis and aligned for discharge of laser energy through the tissue opposing surface.

Abstract: A method and apparatus for forming a lesion in tissue along a desired ablation path with treating a body tissue in situ (e.g., an atrial tissue of a heart to treat) atrial fibrillation include a lesion formation tool including is positioned against the heart surface. The lesion formation tool includes a guide member having a tissue-opposing surface for placement against a heart surface. An ablation member is coupled to the guide member to move in a longitudinal path relative to the guide member. The guide member includes a track. A carriage is slidably received with the track. The ablation member is secured to the carriage for movement therewith. The guide member includes a visualization component.

Abstract: A method and apparatus for treating a body tissue in situ (e.g., an atrial tissue of a heart to treat) atrial fibrillation include a lesion formation tool is positioned against the heart surface. The lesion formation tool includes a guide member having a tissue-opposing surface for placement against a heart surface. An ablation member is coupled to the guide member to move in a longitudinal path relative to the guide member. The ablation member has an ablation element for directing ablation energy in an emitting direction away from the tissue-opposing surface. The guide member may be flexible to adjust a shape of the guide member for the longitudinal path to approximate the desired ablation path while maintaining the tissue-opposing surface against the heart surface. In one embodiment, the ablation member includes at least one radiation-emitting member disposed to travel in the longitudinal pathway. Transmurality can be assessed to approximate a location of non-transmurality in a formed lesion.

Abstract: An apparatus for treating a biological tissue of a patient in situ includes an optical fiber for guiding a coherent waveform of a selected wavelength to a fiber tip. The wavelength is selected to have a low absorption in water. The fiber tip is contained within a guide member having a discharge bore to define an unobstructed light pathway. The guide member is adapted to be slidable along a tissue surface in atraumatic sliding engagement with the discharge bore opposing the surface. The guide member is carried on an elongated flexible member.

Abstract: A method and apparatus for treating atrial tissue include positioning a lesion formation tool against the atrial surface. An optical fiber of the tool is energized at a wavelength is selected to have a low absorption in water.

Abstract: An apparatus for forming a lesion in cardiac tissue includes an optical fiber for guiding a coherent waveform of a selected wavelength to a fiber tip. The wavelength is selected to have a low absorption in water. The fiber tip is contained within a guide member having a discharge bore for a direction of energy discharge to define an unobstructed light pathway from the fiber tip through a discharge end of the discharge bore. A fluid pathway is in fluid flow communication with the guide member to admit a bio-compatible flushing fluid to the discharge bore.

Abstract: A bifurcated stent comprises a first stent section and a second stent section. Each stent section is expandable from a predeployed state to a deployed state independently from one another. The second stent section having an end engaged to a receiving region of the first stent section. In the deployed state the first stent section defines a primary flow path and the second stent section defines a secondary flow path in fluid communication with the first flow path. At least a portion of one or both the first stent section and second stent section is constructed from a wire member.

Abstract: Systems for delivering a bifurcated stent to a bifurcation site comprise catheters and/or bifurcated stents delivered therefrom.

Abstract: Systems for delivering a bifurcated stent to a bifurcation site comprise catheters and/or bifurcated stents delivered therefrom.

Abstract: A bifurcated stent comprises a first stent section and a second stent section. Each stent section is expandable from a predeployed state to a deployed state independently from one another. The second stent section having an end engaged to a receiving region of the first stent section. In the deployed state the first stent section defines a primary flow path and the second stent section defines a secondary flow path in fluid communication with the first flow path. At least a portion of one or both the first stent section and second stent section is constructed from a wire member.

Abstract: The present invention relates generally to the area of vascular sealing, and more particularly to a device having an inflatable bladder member placed in conjunction with the exterior of the vessel wall for preventing blood flow.

Abstract: An irrigated tip catheter comprises a catheter body, a tip section, and a porous tip electrode. The catheter body has an outer wall, proximal and distal ends, and a lumen extending therethrough. The tip section comprises a segment of flexible tubing having proximal and distal ends and at least one lumen therethrough. The proximal end of the tip section is fixedly attached to the distal end of the catheter body. The porous tip electrode is fixedly attached to the distal end of the tubing of the tip section. The tip electrode has an outer surface and comprises a body and an insert. The body comprises a porous material through which fluid can pass and has a cavity therein. The insert, which comprises a non-porous material, is contained within the cavity of the shell. The insert has at least one passage extending therethrough in fluid communication with a lumen in the tip section. An infusion tube having proximal and distal ends extends through the central lumen in the catheter body.

Abstract: An ablation catheter is provided which comprises a steerable catheter including a distal portion and a proximal portion. An ablation electrode is carried by the distal portion, with the ablation electrode having structure defining an interior space and having at least one aperture. A positional sensor is located in the interior space, wherein the proximal portion is connected to a source of cooling liquid which flows out of the aperture. The ablation catheter provides a suitable flow of fluid through the aperture while providing a space or volume sufficiently large for placement of a positional sensor.

Abstract: A device and method for making medical balloons such as for angioplasty. The device has fibers that may be of different materials, shapes, sizes, and directions, with the interstitium filled by a polymer materials to render it waterproof and able to be pressurized. The device exhibits improved strength and flexibility. Preferably, the device is steerable, radiopaque, and can operate at very high inflation pressures in order to facilitate low impedance angioplasty.

Abstract: A vascular closure device. In each embodiment, the device includes at least one relatively non-deformable surface member and a conformable and distensible member. Typically the conformable member is implemented as a balloon structure that is inflated with a liquid or gaseous medium. This inflation fluid increases the fluid pressure in the balloon which counteracts the fluid pressure of the punctured vessel. The resulting forces on the balloon are opposed by tissue structures that transfer the load to the surrounding subcutaneous tissue structures. The device may be constructed of bioabsorbable or non-bioabsorbable materials. Additionally, the device may be coated with agents to provide a secondary therapy for enhancement of clotting or prevention of infections. These agents may also elute from the distensible conformal member.

Abstract: The invention relates to an ablation catheter which controls the temperature and reduces the coagulation of biological fluids on a tip of a catheter, prevents the impedance rise of tissue in contact with the catheter tip, and maximizes the potential energy transfer to the tissue, thereby allowing an increase in the lesion size produced by the ablation. The ablation catheter includes a catheter body. The ablation catheter also includes a tip for monitoring electrical potentials, and applying electrical energy to a biological tissue. A fluid source is positioned at one end of the catheter for supplying a fluid flow through the catheter to the tip means. Passages are positioned within the tip in a variety of manners for directing the fluid flow through the tip means to the exterior surface of the tip to control the temperature and form a protective fluid layer around the tip. Monitoring structure is also positioned within the tip structure for measurement of the electrical potentials in a biological tissue.

Abstract: Laser catheters according to the invention include multiple optical fibers for delivery of laser energy to a pre-determined treatment site in the therapeutic treatment of cardiac tissue. A fixation device fixes the distal end of the catheter to the treatment site. Temperature sensing devices disposed on the fixation device provide a temperature depth profile of the tissue treatment site, which can be used to control the treatment. Multi-piece, single-piece and porous tip catheters are disclosed.

Abstract: Cooled optical connector for alignment and coupling of bundled fibers of an optic cable. Coolant in a liquid or gaseous form is passed through a chamber in which a bundled fiber optic cable and nut portion of a standard optical connector is contained. Coolant in either form moves through the cooled optical connector absorbing thermal energy and cooling the interstitial and exposed fibers and areas and the standard optical connector itself.

Abstract: The invention relates to an ablation catheter which controls the temperature and reduces the coagulation of biological fluids on a tip of a catheter, prevents the impedance rise of tissue in contact with the catheter tip, and maximizes the energy transfer to the tissue, thereby allowing an increase in the lesion size produced by the ablation. The ablation catheter includes a tip for applying electrical energy to biological tissue. Passages are positioned within the tip in a variety of manners for directing a fluid flow through the tip to the exterior surface of the tip to control the temperature and form a protective fluid layer around the tip. Monitoring structure is also positioned within the tip for measurement of the electrical potentials in a biological tissue. Ablation electrode structure is also positioned within the tip for application of ablative energy to the biological tissue.

Abstract: The invention relates to a steering system for a catheter tip. The system includes wire members that extend through a catheter wall that are used to pull a distal portion of the catheter tip causing controlled, predetermined bending at the tip. Anchoring members located near the catheter tip connect the distal end of the catheter with wire members. The steering system also contains control members which are located at a proximal portion of the catheter and are used to control the pull on the wire members. Steering enhancement members are also included in the steering system which facilitate the bending of the catheter wall.