Abstract: Methods for producing a composite bone graft material that can regenerate bony defects in the body are provided. Also, methods, kits and delivery systems for a minimally invasive delivery of a composition for regenerating bone at or near the site of a bony defect that include, the composition for regenerating bone comprising collagen and bioactive glass are provided.

Abstract: The present invention relates to combination products including bioactive glass and collagen as well as kits comprising the same.

Abstract: Bone repair composition including a bone repair material suspended in a mixture of non-random poly(oxyalkylene) block copolymer and water exhibiting reverse phase behavior when the temperature increases from room temperature to body temperature. There are many materials used today for the repair and regeneration of bone defects. Bone is a composite of collagen, cells, calcium hydroxyapatite crystals, and small quantities of other proteins of organic molecules that has unique properties of high strength, rigidity, and ability to adapt to varying loads.

Abstract: The invention relates to bioactive glass compositions that include bioactive glass with surface immobilized peptides and methods and uses thereof.

Abstract: Compositions including crosslinked collagen and bioactive glass having an average pore size of at least 100 microns and methods of preparation thereof.

Abstract: An irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and at least one non-ionic surfactant, other than a non-random poly(oxyalkylene) block copolymer, is described. Also, methods for treating a bone having a bone gap or a bone defect with the composition including a biocompatible or bioactive bone repair material and at least one non-ionic surfactant, other than a non-random poly(oxyalkylene) block copolymer, are also provided. Also, kits including the irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and at least one non-ionic surfactant, other than a non-random poly(oxyalkylene) block copolymer, are described.

Abstract: Methods for producing a composite bone graft material that can regenerate bony defects in the body are provided. Also, methods, kits and delivery systems for a minimally invasive delivery of a composition for regenerating bone at or near the site of a bony defect that include, the composition for regenerating bone comprising collagen and bioactive glass are provided.

Abstract: The invention relates to the use of a bioactive glass material. For example, an autograft chip is wrapped in bioactive glass material for the treatment of bone injuries and bone defects in the body. The material can be in one or more of several forms, such as fibers, a fiber mesh, a sheet, or another shape. The material can be applied to hard tissues, such as bone.

Abstract: An irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers is described. Also, methods for treating a bone having a bone gap or a bone defect with the composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers are also provided. Also, kits including the irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers are described.

Abstract: A bioactive spinal implant used in cervical fusion, Anterior Lumbar Interbody Fusion (ALIF), Posterior Lumbar Interbody Fusion (PLIF), and Transforaminal Interbody Fusion (TLIF), having properties and geometries that enhance bone contact, stability, and fusion between adjacent vertebral bodies.

Abstract: A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof, which include introducing Na2O into the glass network during the sol-gel process through the use of Na-ethoxide, NaCl, or sodium silicate rather than sodium nitrate. Medical and industrial uses of such glasses.

Abstract: A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof which include at least 5 weight percent CaO, at least 10 weight percent P2O5, at least 10 weight percent Na2O, and at least 25 weight percent B2O3, wherein the bioactive glass is substantially silica-free. Medical and industrial uses of such glasses.

Abstract: A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof which include introducing Na2O into the glass network during the sol-gel process through the use of Na-ethoxide, NaCl, or sodium silicate rather than sodium nitrate. Medical and industrial uses of such glasses.

Abstract: The present invention relates to combination products including bioactive glass and collagen as well as kits comprising the same.

Abstract: A bioactive spinal implant used in cervical fusion, Anterior Lumbar Interbody Fusion (ALIF), Posterior Lumbar Interbody Fusion (PLIF), and Transforaminal Interbody Fusion (TLIF), having properties and geometries that enhance bone contact, stability, and fusion between adjacent vertebral bodies.

Abstract: One or more particles of bioactive glass coated with a glycosaminoglycan, wherein the glycosaminoglycan is bound to the bioactive glass and methods of treatment using such particles.

Abstract: Compositions including crosslinked collagen and bioactive glass having an average pore size of at least 100 microns and methods of preparation thereof.

Abstract: A composition including calcium salt and silica, wherein the silica is in the form of a silicate that is adsorbed onto the surface of the calcium salt, wherein the silica is not incorporated into the structure of the calcium salt, and wherein the composition is bioactive.

Abstract: The present invention provides polymerizable biocompatible materials stabilized by amino acids or reducing salts to improve shelf life. Methods of stabilizing a polymerizable biocompatible material that inhibit auto polymerization of the material over time are also provided.

Abstract: A bioactive spinal implant used in cervical fusion, Anterior Lumbar Interbody Fusion (ALIF), Posterior Lumbar Interbody Fusion (PLIF), and Transforaminal Interbody Fusion (TLIF), having properties and geometries that enhance bone contact, stability, and fusion between adjacent vertebral bodies.