Abstract: One aspect of the present disclosure relates to a system that can measure profusion through a volume of tissue. The system can include a non-transitory memory that stores instructions and a processor that can be configured to execute the instructions to at least: receive an ultrasound signal response of a contrast agent within a volume of interest and determine the perfusion through the volume of tissue based on a probabilistic constant related to the geometry, the tissue density, the ultrasound signal response, and a feature of the geometry. The ultrasound signal response can include a time dimension and three position dimensions. The volume of interest can include a tissue density and a geometry.

Abstract: One aspect of the present disclosure relates to a system that can measure profusion through a volume of tissue. The system can include a non-transitory memory that stores instructions and a processor that can be configured to execute the instructions to at least: receive an ultrasound signal response of a contrast agent within a volume of interest and determine the perfusion through the volume of tissue based on a probabilistic constant related to the geometry, the tissue density, the ultrasound signal response, and a feature of the geometry. The ultrasound signal response can include a time dimension and three position dimensions. The volume of interest can include a tissue density and a geometry.

Abstract: A method of delivering ultrasound signals using shear waves includes applying a portion of at least a first ultrasound beam to a subject at at least a first incident angle relative to the surface of the subject to induce shear waves in the subject, energy in the shear waves forming a substantial part of energy of first ultrasound waves at a desired region in the subject at a therapeutic level.

Abstract: A method of diagnosing a subject by delivering ultrasound signals using shear waves includes applying a portion of an ultrasound mainbeam to a bone surface at an incident angle relative to the surface of the bone to induce shear waves in the bone, energy in the shear waves forming a substantial part of energy of first ultrasound waves at a desired region in the subject through the bone, detecting at least one of reflected and scattered energy of the applied ultrasound mainbeam, and analyzing the detected energy for a diagnostic purpose.

Abstract: A method of delivering ultrasound signals using shear waves includes applying a portion of at least a first ultrasound beam to a subject at at least a first incident angle relative to the surface of the subject to induce shear waves in the subject, energy in the shear waves forming a substantial part of energy of first ultrasound waves at a desired region in the subject at a therapeutic level.

Abstract: A method of diagnosing a subject by delivering ultrasound signals using shear waves includes applying a portion of an ultrasound mainbeam to a bone surface at an incident angle relative to the surface of the bone to induce shear waves in the bone, energy in the shear waves forming a substantial part of energy of first ultrasound waves at a desired region in the subject through the bone, detecting at least one of reflected and scattered energy of the applied ultrasound mainbeam, and analyzing the detected energy for a diagnostic purpose.

Abstract: A method of delivering ultrasound signals includes providing an image of at least a portion of a subject intended to receive ultrasound signals between sources of the ultrasound signals and a desired region of the subject for receiving focused ultrasound signals, identifying, from the image, physical characteristics of portions of material between the sources and the desired region, and using a spectral propagation analysis to determine at least one of phase corrections and amplitude corrections for the sources depending on the respective physical characteristics of the portions of the material disposed between each source and the desired region.

Abstract: A method of delivering ultrasound signals includes providing an image of at least a portion of a subject intended to receive ultrasound signals between sources of the ultrasound signals and a desired region of the subject for receiving focused ultrasound signals, identifying, from the image, physical characteristics of portions of material between the sources and the desired region, and using a spectral propagation analysis to determine at least one of phase corrections and amplitude corrections for the sources depending on the respective physical characteristics of the portions of the material disposed between each source and the desired region.