Patents by Inventor Guangrong Zhang
Guangrong Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12118414Abstract: The present disclosure provides compositions and methods for selectively killing cancer cells, wherein the composition comprises a compound of Formula (I). The selective killing of cancer cells occurs with an improved potency and safety profile compared to similar compounds. In particular, the compositions and methods of the invention show reduced platelet toxicity and retained or improved toxicity in cancer cells.Type: GrantFiled: January 22, 2019Date of Patent: October 15, 2024Assignee: BIOVENTURES, LLCInventors: Guangrong Zheng, Daohong Zhou, Xuan Zhang, Sajid Khan, Yonghan He, Peiyi Zhang
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Patent number: 12084423Abstract: The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the composition comprises piperlongumine derivative thereof. The selective killing of senescent cells may delay aging and/or treat age-related disorders.Type: GrantFiled: May 18, 2018Date of Patent: September 10, 2024Assignee: BioVentures, LLCInventors: Guangrong Zheng, Daohong Zhou, Xuan Zhang
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Patent number: 12075841Abstract: An electronic cigarette encrypted by wireless electronic tag and an encrypting method thereof are provided. The electronic cigarette comprises a vaporizer (1) and a battery assembly (2) connected with each other, the vaporizer (1) comprises a heating resistor (3) and a wireless electronic tag preset with encryption information, the battery assembly (2) comprises a battery (4) and a control circuit board (5) arranged with a microcontroller, a resistance detection unit, a voltage output control unit, a wireless electronic tag reader, and a wireless signal transmitter, wherein the wireless electronic tag reader reads the encryption information and sends it to the microcontroller, and the voltage output control unit outputs voltage to the heating resistor on the premise that the resistance value of the heating resistor is detected by the resistance detection unit and the encryption information is read by the wireless electronic tag reader as well.Type: GrantFiled: December 5, 2019Date of Patent: September 3, 2024Assignee: HUIZHOU HAPPY VAPING TECHNOLOGY LIMITEDInventors: Guangrong Lin, Xianbin Zheng, Xiyong Zhang
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Publication number: 20240263805Abstract: Disclosed is a gas heater, including: a gas bottle for storing a gas, a valve body connector, and a burner. A cavity is provided in the valve body connector, both the regulator and the safety valve are communicated with the cavity, the regulator is connected to the gas bottle, the valve body connector is provided with a valve nozzle, and the valve nozzle is communicated with the cavity. An air inlet pipe is provided between the burner and the valve body connector, one end of the air inlet pipe is connected to the valve nozzle, another end of the air inlet pipe is connected to the burner. The gas enters the cavity of the valve body connector through the regulator, and enters the air inlet pipe through the valve nozzle.Type: ApplicationFiled: May 18, 2023Publication date: August 8, 2024Applicant: SHINERICH INDUSTRIAL LTD.Inventors: Guangrong ZHANG, Hui XIE, Guoming YUAN
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Publication number: 20240240798Abstract: Disclosed is a decorative gas stove. The decorative gas stove includes a stove body and a viewing platform. A cavity is defined in the stove body. An energy device is provided inside the cavity for storing gaseous fuel. A supply pipe is provided inside the cavity for transporting the gaseous fuel. A water tank is provided on an upper end of the stove body and a bottom of the water tank is defined with a plurality of air outlet holes communicated with the supply pipe. An ignition portion is provided on a side wall of the water tank for igniting the gaseous fuel flowing to a water surface through the air outlet holes when the water tank is stored with water.Type: ApplicationFiled: April 24, 2023Publication date: July 18, 2024Applicant: SHINERICH INDUSTRIAL LTD.Inventors: Guangrong ZHANG, Hui PENG
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Publication number: 20240219034Abstract: Disclosed are a flameout protection system and a heater. The flameout protection system includes a stove head, a double-needle electrode rod, an electromagnetic valve and a plasma controller. The stove head is provided with an ejection tube and a flame hole. The double-needle electrode rod is connected to the ejection tube, and one end of the double-needle electrode rod is close to the flame hole. The electromagnetic valve is connected to the ejection tube, and the electromagnetic valve is communicated with the flame hole. The plasma controller is electrically connected to the double-needle electrode rod, and the plasma controller is electrically connected to the electromagnetic valve.Type: ApplicationFiled: April 13, 2023Publication date: July 4, 2024Applicant: SHINERICH INDUSTRIAL LTD.Inventors: Guangrong ZHANG, Cuilong LI
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Publication number: 20240219033Abstract: Disclosed is an outdoor furnace table, including: a box body, an under-table heating portion, a reflecting structure, a fire pan portion and a fuel supply system. The box body is formed with an installation channel, a side end of the box body is provided with a heating hole, an upper end of the box body is provided with a table plate, and the table plate is provided with a fire via port; the under-table heating portion includes a first burner at a lower end of the installation channel; the reflecting structure is provided in the installation channel; the fire pan portion includes a second burner located in the installation channel and above the first burner, a fire generated by the second burner is transmitted through the fire via port; and the fuel supply system is provided in the installation channel.Type: ApplicationFiled: December 27, 2023Publication date: July 4, 2024Applicant: SHINERICH INDUSTRIAL LTD.Inventors: Guangrong ZHANG, Qiong LIANG
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Publication number: 20240023754Abstract: Disclosed is an oven, including a body assembly, an air inlet cylinder and a support member. The body assembly mounted on the support member includes a body, a top cover and an enclosure; the body includes a bottom plate and a side plate which includes a top end and a bottom end; the bottom plate is provided with a first air inlet hole, a side of the side plate near the top end is provided with a second air inlet hole; the enclosure is provided around the side plate, the enclosure, the side plate and the top cover form a first air inlet channel; an inner cavity in the body is communicated with the first air inlet channel through the second air inlet hole; an air inlet cylinder in the inner cavity is provided with a second air inlet channel for air entering the inner cavity from the outside.Type: ApplicationFiled: October 28, 2022Publication date: January 25, 2024Applicant: SHINERICH INDUSTRIAL LTD.Inventors: Guangrong ZHANG, Bo XIE
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Patent number: 10705238Abstract: The present disclosure discloses a method and an apparatus for processing seismic data, and belongs to the field of geological surveys. The method comprises: stacking seismic trace gathers in a predetermined range among S seismic trace gathers after a Normal Move Out (NMO) correction processing to obtain a model trace, S being an integer; calculating a correlation coefficient of each seismic trace gather with the model trace, and selecting a K-th seismic trace gather with a maximum correlation coefficient; calculating an optimum point of each seismic trace gather from the K-th seismic trace gather to two sides orderly; and performing a residual NMO correction of the seismic trace gathers according to the optimum points.Type: GrantFiled: January 29, 2018Date of Patent: July 7, 2020Assignee: PETROCHINA COMPANY LIMITEDInventors: Guangrong Zhang, Fusen Xiao, Qi Ran, Shirong Zhang, Yi Yu, Qi Liao, Bo Ma, Han Liang, Kang Chen, Xuan Zhang, Xiaomin Lu
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Publication number: 20180149764Abstract: The present disclosure discloses a method and an apparatus for processing seismic data, and belongs to the field of geological surveys. The method comprises: stacking seismic trace gathers in a predetermined range among S seismic trace gathers after a Normal Move Out (NMO) correction processing to obtain a model trace, S being an integer; calculating a correlation coefficient of each seismic trace gather with the model trace, and selecting a K-th seismic trace gather with a maximum correlation coefficient; calculating an optimum point of each seismic trace gather from the K-th seismic trace gather to two sides orderly; and performing a residual NMO correction of the seismic trace gathers according to the optimum points.Type: ApplicationFiled: January 29, 2018Publication date: May 31, 2018Inventors: Guangrong ZHANG, Fusen XIAO, Qi RAN, Shirong ZHANG, Yi YU, Qi LIAO, Bo MA, Han LIANG, Kang CHEN, Xuan ZHANG, Xiaomin LU
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Patent number: 9052324Abstract: The present invention relates to the field of therapeutic methods to screen for compounds on the basis of their ability to influence Wnt activity. The screening process is applied to both a physical library of a series of compounds and a virtual library of compounds that affect Wnt activity. In one aspect, the virtual screening process could be carried out where a permutational library of small peptides is substituted for the small organic molecules. The inventive methods may be used to empirically test for effects on Wnt activity and may also be applied to any pair of proteins involved in protein-protein interactions.Type: GrantFiled: May 22, 2009Date of Patent: June 9, 2015Assignee: Enzo Biochem, Inc.Inventors: Dakai Liu, Xiaofeng Li, Richard Jin, Yuaxin Liang, Wei Cheng, Riddhi Bhattacharyya, Guangrong Zhang
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Publication number: 20120322717Abstract: The present invention relates to the field of therapeutic methods to screen for compounds on the basis of their ability to influence Wnt activity. The screening process is applied to both a physical library of a series of compounds and a virtual library of compounds that affect Wnt activity. In one aspect, the virtual screening process could be carried out where a permutational library of small peptides is substituted for the small organic molecules. The inventive methods may be used to empirically test for effects on Wnt activity and may also be applied to any pair of proteins involved in protein-protein interactions.Type: ApplicationFiled: May 22, 2009Publication date: December 20, 2012Inventors: Dakai Liu, Xiaofeng Li, Richard Jin, Yuaxin Liang, Wei Cheng, Riddhi Bhattacharyya, Guangrong Zhang
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Publication number: 20100298200Abstract: The present invention relates to the field of therapeutic methods to screen for compounds on the basis of their ability to influence Wnt activity. The screening process is applied to both a physical library of a series of compounds and a virtual library of compounds that affect Wnt activity. In one aspect, the virtual screening process could be carried out where a permutational library of small peptides is substituted for the small organic molecules. The inventive methods may be used to empirically test for effects on Wnt activity and may also be applied to any pair of proteins involved in protein-protein interactions.Type: ApplicationFiled: May 22, 2009Publication date: November 25, 2010Inventors: Dakai Liu, Xiaofeng Li, Richard Jin, Yuaxin Liang, Wei Cheng, Riddhi Bhattacharyya, Guangrong Zhang
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Patent number: 7070951Abstract: Compositions and methods are provided for dewaxing wax-embedded biological specimens prior to histochemical analysis. The compositions and methods provided can effectively remove wax or improved wax-based embedding materials, particularly paraffin-based, from specimens during preparation for histochemical or other diagnostic analyses, while minimizing danger to users, achieving compatibility with automated use, and maintaining compatibility with downstream histochemical analyses, particularly immunostaining. Compositions of the invention comprise a paraffin-solubilizing organic solvent, a polar organic solvent, and a surfactant. Compositions can further comprise water. The method involves contacting a wax-embedded specimen with the dewaxing composition to solubilize the wax impregnating the specimen prior to histochemical analysis.Type: GrantFiled: August 29, 2003Date of Patent: July 4, 2006Assignee: BioGenex LaboratoriesInventors: Guangrong Zhang, Cheng-Zhi Yu, Sheng-Hui Su, Krishan L. Kalra, Ding Zhou
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Publication number: 20060019332Abstract: Compositions and methods are provided for dewaxing wax-embedded biological specimens prior to histochemical analysis. The compositions and methods provided can effectively remove wax or improved wax-based embedding materials, particularly paraffin-based, from specimens during preparation for histochemical or other diagnostic analyses, while minimizing danger to users, achieving compatibility with automated use, and maintaining compatibility with downstream histochemical analyses, particularly immunostaining. Compositions of the invention comprise a paraffin-solubilizing organic solvent, a polar organic solvent, and a surfactant. Compositions can further comprise water. The method involves contacting a wax-embedded specimen with the dewaxing composition to solubilize the wax impregnating the specimen prior to histochemical analysis.Type: ApplicationFiled: July 20, 2005Publication date: January 26, 2006Inventors: Guangrong Zhang, Cheng-Zhi Yu, Sheng-Hui Su, Krishan Kalra, Ding Zhou
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Publication number: 20040172380Abstract: The present invention provides an automatic cooking method and system, wherein the cooking process of a chef is recorded. Then, a program about the cooking process is obtained with information about amounts and kinds of main ingredients and seasoning materials used by the chef, timing of adding main ingredients and seasoning materials and movement tracks of the cooking container and shovel. Thereafter, manipulators of a mechanical operating system of the present invention imitate chef's cooking process according to commend signal from the program to produce a dish. The present invention uses recording devices to record chef's cooking process and provide a program, then respective mechanical operating system accomplishes cooking tasks imitating the chef, which provides restaurants and households with dishes by the chef when using the program and mechanical operating system.Type: ApplicationFiled: March 8, 2004Publication date: September 2, 2004Inventors: Xiaolin Zhang, Guangrong Zhang
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Publication number: 20040126399Abstract: Compositions and methods are provided for dewaxing wax-embedded biological specimens prior to histochemical analysis. The compositions and methods provided can effectively remove wax or improved wax-based embedding materials, particularly paraffin-based, from specimens during preparation for histochemical or other diagnostic analyses, while minimizing danger to users, achieving compatibility with automated use, and maintaining compatibility with downstream histochemical analyses, particularly immunostaining. Compositions of the invention comprise a paraffin-solubilizing organic solvent, a polar organic solvent, and a surfactant. Compositions can further comprise water. The method involves contacting a wax-embedded specimen with the dewaxing composition to solubilize the wax impregnating the specimen prior to histochemical analysis.Type: ApplicationFiled: August 29, 2003Publication date: July 1, 2004Inventors: Guangrong Zhang, Cheng-Zhi Yu, Sheng-Hui Su, Krishan L. Kalra, Ding Zhou
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Patent number: 6632598Abstract: Compositions and methods are provided for dewaxing wax-embedded biological specimens prior to histochemical analysis. The compositions and methods provided can effectively remove wax or improved wax-based embedding materials, particularly paraffin-based, from specimens during preparation for histochemical or other diagnostic analyses, while minimizing danger to users, achieving compatibility with automated use, and maintaining compatibility with downstream histochemical analyses, particularly immunostaining. Compositions of the invention comprise a paraffin-solubilizing organic solvent, a polar organic solvent, and a surfactant. Compositions can further comprise water. The method involves contacting a wax-embedded specimen with the dewaxing composition to solubilize the wax impregnating the specimen prior to histochemical analysis.Type: GrantFiled: March 11, 1994Date of Patent: October 14, 2003Assignee: BioGenex LaboratoriesInventors: Guangrong Zhang, Cheng-Zhi Yu, Sheng-Hui Su, Krishan L. Kalra, Ding Zhou
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Patent number: 6538128Abstract: The invention provides improved processes for oligonucleotide synthesis utilizing arenes as solvents for detritylation of oligonucleotides.Type: GrantFiled: March 22, 1999Date of Patent: March 25, 2003Assignee: Avecia Biotechnology, Inc.Inventors: Guangrong Zhang, Jin-Yan Tang
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Patent number: 5128476Abstract: Reagents of the formula I ##STR1## wherein A is --CH.sub.2 --.sub.m O-- (m=2 to 20) or --C.sub.n H.sub.2n --O--.sub.t (n=2 to 6; t=2 to 10) and B is selected from the group consisting of ##STR2## and salts thereof are useful for the preparation of 5'-biotinylated oligonucleotides.Type: GrantFiled: February 20, 1991Date of Patent: July 7, 1992Assignee: The Midland Certified Reagent CompanyInventors: Guangrong Zhang, Richard V. Case