Patents by Inventor Guanhua Du

Guanhua Du has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inclusion complexes of pinocembrin with cyclodextrin or its derivatives
    Patent number: 9949946
    Abstract: Inclusion complexes of pinocembrin with cyclodextrin or its derivatives and their preparation are provided. The inclusion complexes can be used to make drugs.
    Type: Grant
    Filed: November 11, 2008
    Date of Patent: April 24, 2018
    Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
    Inventors: Song Wu, Guanhua Du, Yan Qi, Mei Gao, Qingyun Yang, Hongmei Guang, Wei Li, Yuehua Wang, Yuanfeng Tong
  • Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods of preparing the same and use of the same
    Patent number: 9199912
    Abstract: The present disclosure relates to polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: December 1, 2015
    Assignees: SHANDONG LUYE PHARMACEUTICAL CO., LTD.
    Inventors: Youxin Li, Wanhui Liu, Yang Lv, Guanhua Du, Qingguo Meng, Mina Yang, Fengmei Zhou, Ju Li, Xuemei Zhang
  • POLYMORPHS OF 4-[2-DIMETHYLAMINO-1-(1-HYDROXYCYCLOHEXYL)ETHYL]PHENYL 4-METHYLBENZOATE HYDROCHLORIDE, METHODS OF PREPARING THE SAME AND USE OF THE SAME
    Publication number: 20140235728
    Abstract: The present disclosure relates to polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same.
    Type: Application
    Filed: April 23, 2014
    Publication date: August 21, 2014
    Applicants: Shandong Luye Pharmaceutical Co., Ltd.
    Inventors: Youxin Li, Wanhui Liu, Yang Lv, Guanhua Du, Qingguo Meng, Mina Yang, Fengmei Zhou, Ju Li, Xuemei Zhang
  • Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methyl-benzoate hydrochloride, methods for preparing the same and use of the same
    Patent number: 8741952
    Abstract: The present disclosure relates to polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: June 3, 2014
    Assignees: Shangong Luye Pharmaceutical Co., Ltd.
    Inventors: Youxin Li, Wanhui Liu, Yang Lv, Guanhua Du, Qingguo Meng, Mina Yang, Fengmei Zhou, Ju Li, Xuemei Zhang
  • Two types of crystalline of pinocembrin, their preparation and their use for manufacture of pharmaceutical compositions
    Patent number: 8399511
    Abstract: Two crystalline forms of pinocembrin of formula (I): ? and ?, their preparation and their use for manufacture of pharmaceutical compositions. There exists difference between them in bioavailability. They are used for treating and preventing cerebral ischemic diseases by protective action of neurovascular unit, and enhancing blood drug level in vivo.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: March 19, 2013
    Assignees: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Institute of Materia Medica, Chinese Academy of Medical Sciences
    Inventors: Guanhua Du, Yang Lv, Song Wu, Ke Wang, Ying Chang, Zhihong Yang, Yuanfeng Tong, Mei Gao
  • Method for resolution of a mixture of pinocembrin optical isomers, especially a pinocembrin racemate
    Patent number: 8399691
    Abstract: The present invention relates to a method for resolution of a mixture of pinocembrin optical isomers, in particular a pinocembrin racemate, using a chiral primary amine or a chiral sulfinamide. The present invention also relates to a (R)-(+)-pinocembrin obtained by the method.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: March 19, 2013
    Assignees: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co. Ltd., Institute of Materia Medica, Chinese Academy of Medical Sciences
    Inventors: Song Wu, Guanhua Du, Yue Yuan, Qingyun Yang, Mei Gao, Yan Qi, Yuanfeng Tong, Yuehua Wang
  • USE OF RACEMATES OF PINOCEMBRIN IN PREPARING MEDICAMENTS FOR TREATING STROKE
    Publication number: 20110245334
    Abstract: Use of a racemate of pinocembrin, a racemate of pinocembrin salt, a racemate of pinocembrin precursor or a racemate of pinocembrin hydrate in manufacture of a medicament for prophylaxis and treatment of stroke. Particularly, use of pinocembrin racemate in manufacture of a medicament for treatment of acute ischemic stroke.
    Type: Application
    Filed: December 10, 2009
    Publication date: October 6, 2011
    Applicant: CSPC Zhonggi Pharmaceutical Technology (Shijiazhuang) Co. Ltd.
    Inventors: Guanhua Du, Jinxu Wang, Song Wu, Ying Shi, Mei Gao, Yingui Li, Yan Qi, Dongmin Shen, Hongmei Guang, Haili Liu, Rui Liu, Xiaolong Feng
  • INCLUSION COMPLEXES OF PINOCEMBRIN WITH CYCLODEXTRIN OR ITS DERIVATIVES
    Publication number: 20110218173
    Abstract: Inclusion complexes of pinocembrin with cyclodextrin or its derivatives and their preparation are provided. The inclusion complexes can be used to make drugs.
    Type: Application
    Filed: November 11, 2008
    Publication date: September 8, 2011
    Inventors: Song Wu, Guanhua Du, Yan Qi, Mei Gao, Qingyun Yang, Hongmei Guang, Wei Li, Yuehua Wang, Yuanfeng Tong
  • TWO TYPES OF CRYSTALLINE OF PINOCEMBRIN, THEIR PREPARATION AND THEIR USE FOR MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS
    Publication number: 20110213024
    Abstract: Two crystalline forms of pinocembrin of formula (I): ? and ?, their preparation and their use for manufacture of pharmaceutical compositions. There exists difference between them in bioavailability. They are used for treating and preventing cerebral ischemic diseases by protective action of neurovascular unit, and enhancing blood drug level in vivo.
    Type: Application
    Filed: November 13, 2008
    Publication date: September 1, 2011
    Applicant: CSPC Zhongqi West Road Shijazhuang
    Inventors: Guanhua Du, Yang Lv, Song Wu, Ke Wang, Ying Chang, Zhihong Yang, Yuanfeng Tong, Mei Gao
  • METHOD FOR RESOLUTION OF A MIXTURE OF PINOCEMBRIN OPTICAL ISOMERS, ESPECIALLY A PINOCEMBRIN RACEMATE
    Publication number: 20100261916
    Abstract: The present invention relates to a method for resolution of a mixture of pinocembrin optical isomers, in particular a pinocembrin racemate, using a chiral primary amine or a chiral sulfinamide. The present invention also relates to a (R)-(+)-pinocembrin obtained by the method.
    Type: Application
    Filed: November 7, 2008
    Publication date: October 14, 2010
    Applicant: CSPC Zhonggi Pharmaceutical Technology (Shijiazhuang) Co. Ltd.
    Inventors: Song Wu, Guanhua Du, Yue Yuan, Qingyun Yang, Mei Gao, Yan Qi, Yuanfeng Tong, Yuehua Wang