Patents by Inventor Guenther LOIDL

Guenther LOIDL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid phase synthesis of acylated peptides
    Patent number: 11186608
    Abstract: The present invention relates to methods and compounds for the solid phase synthesis of peptides carrying a substituent at an amino group of an amino acid side chain.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: November 30, 2021
    Assignee: Bachem Holding AG
    Inventors: Ralph O. Schoenleber, Guenther Loidl
  • Method for preparing glucagon-like peptides
    Patent number: 11117946
    Abstract: The present invention refers to a method for preparing a glucagon-like peptide, comprising precipitation of the peptide or of a precursor peptide by means of mixing with an anti-solvent comprising diisopropyl ether and acetonitrile. Further, the present invention also relates to a peptide conjugated to a solid phase and a pharmaceutical composition comprising a Liraglutide peptide obtainable from a method according to the present invention.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: September 14, 2021
    Inventors: Guenther Loidl, Benjamin Neuhaus, Ralph O. Schoenleber, Andreas Stadelmaier
  • MANUFACTURE OF GLUCAGON PEPTIDES
    Publication number: 20210122782
    Abstract: The present invention refers to a method of purifying a glucagon peptide, the method comprising a two dimensional reversed phase high performance liquid chromatography protocol, wherein the first step is carried out at using a mobile phase comprising a triethylammonium phosphate (TEAP) buffer and acetonitrile, and the second step is carried out at using a mobile phase comprising aqueous acetic acid and acetonitrile.
    Type: Application
    Filed: January 30, 2019
    Publication date: April 29, 2021
    Inventors: Ralf EISENHUTH, Guenther LOIDL, Daniel SAMSON, Ralph O. SCHOENLEBER
  • SOLID PHASE SYNTHESIS OF ACYLATED PEPTIDES
    Publication number: 20210009631
    Abstract: The present invention relates to methods and compounds for the solid phase synthesis of peptides carrying a substituent at an amino group of an amino acid side chain.
    Type: Application
    Filed: July 10, 2018
    Publication date: January 14, 2021
    Applicant: Bachem Holding AG
    Inventors: Ralph O. SCHÖNLEBER, Günther LOIDL
  • METHOD FOR PREPARING GLUCAGON-LIKE PEPTIDES
    Publication number: 20190100569
    Abstract: The present invention refers to a method for preparing a glucagon-like peptide, comprising precipitation of the peptide or of a precursor peptide by means of mixing with an anti-solvent comprising diisopropyl ether and acetonitrile. Further, the present invention also relates to a peptide conjugated to a solid phase and a pharmaceutical composition comprising a Liraglutide peptide obtainable from a method according to the present invention.
    Type: Application
    Filed: March 21, 2017
    Publication date: April 4, 2019
    Inventors: Guenther LOIDL, Benjamin NEUHAUS, Ralph O. SCHOENLEBER, Andreas STADELMAIER