Abstract: The present invention concerns a device for detecting gases or volatile organic compounds (VOC) comprising an electrically conducting or semiconducting zone functionalized with an organic film resulting from the polymerization of aromatic diazonium salt derived monomer.

Abstract: The invention relates to the use of disubstituted alkynes for the functionalisation of the surface of a substrate consisting of a semi-conductor material, with molecules of interest. According to the invention, a compound of formula A-(E1)n1-F1 is used, wherein A is a linear or cyclic disubstituted alkyne, E1 is an alkyl chain and n2 is 0 or 1, and F1 is a reactive group that can react with the reactive group F2 of a compound of formula F2-(E2)n2-X wherein E2 is an alkyl chain and X is a group having properties of interest. The invention is especially applicable to the field of molecular biology or biotechnology.

Abstract: The invention relates to compounds comprising a cycloalkyne or heterocycloalkyne group and a redox group. Said compounds are of general formula (I) wherein Z is a cycloalkyne or heterocycloalkyne with at least 8 links, optionally substituted by a halogen atom or a linear or branched C1 to C5 alkyl, A is an organic structure having oxidation-reduction properties, and B is an organic link between the cycloalkyne or heterocycloalkyne cycle and the organic structure A. The invention is especially applicable to the field of molecular electronics.

Abstract: The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound of the invention corresponds to the formula X-E-A-Z where X is a silyl group, E is an organic spacer group, A is a single bond or a —CONH—, —NHCO—, —OCH2CONH—, —NHCOCH2O—, —O— or —S— group, and Z is a cycloalkyne or heterocycloalkyne with at least 8 members. The invention is particularly suitable for use in the field of medicine.

Abstract: The present invention concerns a device for detecting gases or volatile organic compounds (VOC) comprising an electrically conducting or semiconducting zone f unctionalized with an organic film resulting from the polymerization of aromatic diazonium salt derived monomer.

Abstract: A microfluidic system including: a substrate, one surface of which is covered with electrodes configured to move, under effect of an electric field, microdrops of a liquid phase including at least one functionalized ionic liquid; and capillaries for introducing a liquid extraction fluid onto the surface and for extracting the liquid extraction fluid from an orifice by forced convection, to obtain an extraction bath located on the surface for extraction of at least one chemical or biological compound from the liquid phase, and the bath is open to a surrounding space on at least two of its opposite sides, for moving, in contact with the surface, the microdrop upstream and downstream of the bath.

Abstract: The invention relates to a detection device of small size, allowing direct in situ detection of particles with no labelling, enabling the particles to be rapidly analysed, and having both a specificity and a sensitivity that are at least equivalent to the existing devices. In one embodiment, the invention provides a device having a nanowire, intended for interacting with the particles of interest, which is suspended between two anchors that define a source and a drain, the source and the drain are configured to be connected to an AC voltage generator and to a DC voltage generator, respectively, in order to generate a first input signal; an excitation electrode, placed laterally facing the nanowire and configured to be connected to an AC voltage generator, in order to generate a second input signal; and a measurement electrode placed opposite the excitation electrode relative to the nanowire and generating a single output signal representative of the particles of interest.

Abstract: The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound of the invention corresponds to the formula X-E-A-Z where X is a silyl group, E is an organic spacer group, A is a single bond or a —CONH—, —NHCO—, —OCH2CONH—, —NHCOCH2O—, —0— or —S— group, and Z is a cycloalkyne or heterocycloalkyne with at least 8 members. The invention is particularly suitable for use in the field of medicine.

Abstract: The invention relates to the use of disubstituted alkynes for the functionalisation of the surface of a substrate consisting of a semi-conductor material, with molecules of interest. According to the invention, a compound of formula A-(E1)n1-F1 is used, wherein A is a linear or cyclic disubstituted alkyne, E1 is an alkyl chain and n2 is 0 or 1, and F1 is a reactive group that can react with the reactive group F2 of a compound of formula F2-(E2)n2-X wherein E2 is an alkyl chain and X is a group having properties of interest. The invention is especially applicable to the field of molecular biology or biotechnology.

Abstract: The invention relates to compounds comprising a cycloalkyne or heterocycloalkyne group and a redox group. Said compounds are of general formula (I) wherein Z is a cycloalkyne or heterocycloalkyne with at least 8 links, optionally substituted by a halogen atom or a linear or branched C1 to C5 alkyl, A is an organic structure having oxidation-reduction properties, and B is an organic link between the cycloalkyne or heterocycloalkyne cycle and the organic structure A. The invention is especially applicable to the field of molecular electronics.

Abstract: The invention relates to a silicon substrate functionalised with molecules having redox properties, the production method thereof and a hybrid molecular memory system including same. The silicon substrate includes: a layer of silicon coated on at least one surface with a layer of silicon oxide, said silicon oxide layer being functionalised with R groups having redox properties; and at least one spacer E having one end bound to the silicon oxide layer and one end bound to an R group. The invention is particularly suitable for use in the field of hybrid molecular memory systems.

Abstract: A method for extracting at least one chemical or biological compound from a liquid phase including at least one functionalized ionic liquid, via a liquid extracting fluid that is miscible with the ionic liquid, and a microfluidic system implementing the method. The extraction method includes moving, on one surface of a microfluidic system, at least one microdrop of the liquid phase into an extraction solution that includes the extracting fluid and that is localized on the surface to obtain in output of the solution, under effect of an electric field, an extract moving away from the surface that is rich in extracting fluid and enriched in the at least one compound, and a raffinate moving on the surface that is rich in ionic liquid and deleted in the at least one compound.

Abstract: Improved method to fabricate a microelectronic device provided with at least one circuit to detect biological elements, comprising the steps of: a) forming transistors, depositing at least one layer in at least one insulating material (141) coating said transistors, forming one or more holes (143) in said layer of insulating material (141), so as to expose the upper face of the respective gate (135) of first-type transistors, filling the holes with a gate material, b) removing, at least in part, the respective gate (135) of the first-type transistors, whilst the gate of second-type transistors is protected, the method prior to or at the same time as said removal conducted at step b) further comprising the removal of said gate material.

Abstract: The invention concerns a method for grafting molecules of interest on a silicon substrate via a spacer compound, said grafting including at least one click chemistry reaction to the supports thus obtained as well as their uses in nanotechnologies and nanobiotechnologies, such as molecular electronics, the manufacture of biochips or of sensors.

Abstract: A method for extracting at least one chemical or biological compound from a liquid phase including at least one functionalized ionic liquid, via a liquid extracting fluid that is miscible with the ionic liquid, and a microfluidic system implementing the method. The extraction method includes moving, on one surface of a microfluidic system, at least one microdrop of the liquid phase into an extraction solution that includes the extracting fluid and that is localized on the surface to obtain in output of the solution, under effect of an electric field, an extract moving away from the surface that is rich in extracting fluid and enriched in the at least one compound, and a raffinate moving on the surface that is rich in ionic liquid and deleted in the at least one compound.

Abstract: The invention relates to a detection device of small size, allowing direct in situ detection of particles with no labelling, enabling the particles to be rapidly analysed, and having both a specificity and a sensitivity that are at least equivalent to the existing devices. In one embodiment, the invention provides a device having a nanowire, intended for interacting with the particles of interest, which is suspended between two anchors that define a source and a drain, the source and the drain are configured to be connected to an AC voltage generator and to a DC voltage generator, respectively, in order to generate a first input signal; an excitation electrode, placed laterally facing the nanowire and configured to be connected to an AC voltage generator, in order to generate a second input signal; and a measurement electrode placed opposite the excitation electrode relative to the nanowire and generating a single output signal representative of the particles of interest.

Abstract: Improved method to fabricate a microelectronic device provided with at least one circuit to detect biological elements, comprising the steps of: a) forming transistors, depositing at least one layer in at least one insulating material (141) coating said transistors, forming one or more holes (143) in said layer of insulating material (141), so as to expose the upper face of the respective gate (135) of first-type transistors, filling the holes with a gate material, b) removing, at least in part, the respective gate (135) of the first-type transistors, whilst the gate of second-type transistors is protected, the method prior to or at the same time as said removal conducted at step b) further comprising the removal of said gate material.

Abstract: The invention relates to a micropump for which the pressure force is not limited by the electrowetting saturation angle, while being simple to manufacture. According to the invention, the microchannel (10) comprises an inlet orifice (11) and has a hydrophilic wall (12) extending from said inlet orifice (11). Displacement means are provided to displace a droplet (51) of liquid (L1) by electrowetting on a hydrophobic surface (22) until said droplet (51) is brought into contact with said hydrophilic wall (12), such that said droplet (51) enters into said microchannel (10) through said inlet orifice (11) by wetting, causing displacement of said fluid (F1).

Abstract: The invention concerns a method for grafting molecules of interest on a silicon substrate via a spacer compound, said grafting including at least one click chemistry reaction to the supports thus obtained as well as their uses in nanotechnologies and nanobiotechnologies, such as molecular electronics, the manufacture of biochips or of sensors.

Abstract: A method for successively functionalizing a substrate whose surface is provided with at least two areas (1, 2) made up of different materials, with at least one chemical substrate, characterized in that the functionalization is carried out without masking and consists (a) in functionalizing a first area (1) without masking the second area (2) or possible successive areas by transforming the substrate with the aid of a chemical substance X1, wherein the first area material reactivity is greater with respect to the reactivity of the substance X1 than the reactivity of the other possible successive areas with respect thereto, and (b1) in treating the second area (2) or the other possible successive areas with a chemical substance Y1 for removing reaction products deposited on said areas during the functionalization from the areas of the substance X1 and/or the possible successive areas without damaging the functionalized surface of the first area.