Patents by Inventor Guillaume Rigaut
Guillaume Rigaut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11554170Abstract: The present invention provides for novel immunological and vaccine formulations comprising a newly applied non-crosslinked polyacrylic acid polymer adjuvant. The adjuvants may be combined with a wide variety of immunogens to produce vaccines that are safe and effective when administered to a wide range of target animals. The immunogens may include, but are not limited to: inactivated pathogens, attenuated pathogens, subunits, recombinant expression vectors, plasmids or combinations thereof. The animals may include, but are not limited to: humans, murine, canines, felines, equines, porcines, ovines, caprines and bovines.Type: GrantFiled: June 15, 2017Date of Patent: January 17, 2023Assignees: Sanofi Pasteur SA, Boehringer Ingelheim Animal Health USA Inc.Inventors: Guillaume Rigaut, Alexis Guy André Lucien Parisot, Karelle De Luca, Christine Michele Pierrette Andreoni, Lydie Remolue, Marie Garinot, Jean-François Cotte, Patricia Probeck-Quellec, Jean Haensler, Véronique Chambon, Philippe Talaga
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Patent number: 10583154Abstract: The present invention relates to non-mercurial preservatives, including antimicrobial polyamide polymers and octenidine, and to methods of use thereof to produce preservative-containing multi-dose formulations. The preservative-containing multi-dose formulations exhibit resistance to one or more contaminating microorganisms, and have advantageous properties with respect to long term stability of biological and small molecule active ingredients.Type: GrantFiled: April 13, 2017Date of Patent: March 10, 2020Assignees: Boehringer Ingelheim Animal Health USA Inc., GENZYME CORPORATIONInventors: Guillaume Rigaut, Celine Loss-Dunod, Alexis Guy Andre Lucien Parisot, Pradeep K. Dhal
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Publication number: 20170360923Abstract: The present invention provides for novel immunological and vaccine formulations comprising a newly applied non-crosslinked polyacrylic acid polymer adjuvant. The adjuvants may be combined with a wide variety of immunogens to produce vaccines that are safe and effective when administered to a wide range of target animals. The immunogens may include, but are not limited to: inactivated pathogens, attenuated pathogens, subunits, recombinant expression vectors, plasmids or combinations thereof. The animals may include, but are not limited to: humans, murine, canines, felines, equines, porcines, ovines, caprines and bovines.Type: ApplicationFiled: June 15, 2017Publication date: December 21, 2017Applicants: MERIAL INC., Sanofi PasteurInventors: Guillaume Rigaut, Alexis Guy André Lucien Parisot, Karelle De Luca, Christine Michele Pierrette Andreoni, Lydie Remolue, Marie Garinot, Jean-François Cotte, Patricia Probeck-Quellec, Jean Haensler, Véronique Chambon, Philippe Talaga
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Publication number: 20170296577Abstract: The present invention relates to non-mercurial preservatives, including antimicrobial polyamide polymers and octenidine, and to methods of use thereof to produce preservative-containing multi-dose formulations. The preservative-containing multi-dose formulations exhibit resistance to one or more contaminating microorganisms, and have advantageous properties with respect to long term stability of biological and small molecule active ingredients.Type: ApplicationFiled: April 13, 2017Publication date: October 19, 2017Applicants: MERIAL INC., GENZYME CORPORATIONInventors: Guillaume Rigaut, Celine Loss-Dunod, Alexis Guy Andre Lucien Parisot, Pradeep K. Dahl
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Patent number: 9730987Abstract: The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified (crude extracts) or minimally purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and, in particular, an immunogen selected from the group consisting of an inactivated pathogen, an attenuated pathogen, a subunit, a recombinant expression vector, and a plasmid or combinations thereof.Type: GrantFiled: February 26, 2015Date of Patent: August 15, 2017Assignee: MERIAL INC.Inventors: Noel Joseph Francois Detraz, Guillaume Rigaut
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Patent number: 9107859Abstract: The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified (crude extracts) or minimally purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and, in particular, an immunogen selected from the group consisting of an inactivated pathogen, an attenuated pathogen, a subunit, a recombinant expression vector, and a plasmid or combinations thereof.Type: GrantFiled: September 9, 2010Date of Patent: August 18, 2015Assignee: MERIAL, INC.Inventors: Noel Joseph Francois Detraz, Guillaume Rigaut
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Publication number: 20150196487Abstract: The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified (crude extracts) or minimally purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and, in particular, an immunogen selected from the group consisting of an inactivated pathogen, an attenuated pathogen, a subunit, a recombinant expression vector, and a plasmid or combinations thereof.Type: ApplicationFiled: February 26, 2015Publication date: July 16, 2015Applicant: MERIAL LIMITEDInventors: Noel Joseph Francois Detraz, Guillaume Rigaut
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Publication number: 20110129494Abstract: The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified (crude extracts) or minimally purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and, in particular, an immunogen selected from the group consisting of an inactivated pathogen, an attenuated pathogen, a subunit, a recombinant expression vector, and a plasmid or combinations thereof.Type: ApplicationFiled: September 9, 2010Publication date: June 2, 2011Inventors: Noel Joseph Francois Detraz, Guillaume Rigaut
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Patent number: 7829323Abstract: The invention relates to flow-through devices for mixing fluids and uses thereof for mixing and for lysing cells to release biological compounds of interest. The invention particularly encompasses flow-through methods for mixing and chemical methods for the isolation and purification of plasmid DNA from cell culture.Type: GrantFiled: November 28, 2005Date of Patent: November 9, 2010Assignee: Merial LimitedInventors: Noel Joseph Francois Detraz, Guillaume Rigaut
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Patent number: 7658341Abstract: The present invention encompasses a flow-through dispersion device for the dispersion of cell aggregates, the device comprising a first or upstream inlet obstacle and a second or downstream outlet obstacle, each obstacle having at least one traversing hole wherein no two holes align. Between the two obstacles is a turbulence chamber, such that when a cell suspension is passed through the inlet holes, into the chamber and then exits the second obstacle, the turbulence within the chamber disrupts and disperses cell aggregates. The device optionally may have more than two obstacles and turbulence chambers and multiple units may be placed in series to increase the amount of turbulence and time applied to a volume of cells. The invention further encompasses methods of using the device to disperse cell aggregates, and methods of culturing cells that involve seeding cultures and maintaining dispersed individual cells.Type: GrantFiled: October 10, 2007Date of Patent: February 9, 2010Assignee: Merial LimitedInventor: Guillaume Rigaut
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Publication number: 20090042216Abstract: The present invention relates to a method for detecting and/or unifying proteins and/or biomolecule or protein complexes, as well as fusion proteins, nucleic acids, vectors and cells suitable for this method.Type: ApplicationFiled: June 3, 2008Publication date: February 12, 2009Inventors: Bertrand Seraphin, Guillaume Rigaut
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Publication number: 20080108137Abstract: The present invention encompasses a flow-through dispersion device for the dispersion of cell aggregates, the device comprising a first or upstream inlet obstacle and a second or downstream outlet obstacle, each obstacle having at least one traversing hole wherein no two holes align. Between the two obstacles is a turbulence chamber, such that when a cell suspension is passed through the inlet holes, into the chamber and then exits the second obstacle, the turbulence within the chamber disrupts and disperses cell aggregates. The device optionally may have more than two obstacles and turbulence chambers and multiple units may be placed in series to increase the amount of turbulence and time applied to a volume of cells. The invention further encompasses methods of using the device to disperse cell aggregates, and methods of culturing cells that involve seeding cultures and maintaining dispersed individual cells.Type: ApplicationFiled: October 10, 2007Publication date: May 8, 2008Inventor: Guillaume Rigaut
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Publication number: 20060166307Abstract: The invention relates to flow-through devices for mixing fluids and uses thereof for mixing and for lysing cells to release biological compounds of interest. The invention particularly encompasses flow-through methods for mixing and chemical methods for the isolation and purification of plasmid DNA from cell culture.Type: ApplicationFiled: November 28, 2005Publication date: July 27, 2006Inventors: Noel Detraz, Guillaume Rigaut
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Publication number: 20020061513Abstract: The present invention relates to a method for detecting and/or unifying proteins and/or biomolecule or protein complexes, as well as fusion proteins, nucleic acids, vectors and cells suitable for this method.Type: ApplicationFiled: February 16, 2001Publication date: May 23, 2002Applicant: Europaisches Laboratorium Fur Molekularbiologie ( EMBL)Inventors: Bertrand Seraphin, Guillaume Rigaut