Abstract: In a sealing machine a pair of juxtaposed foils are sealed together at web regions having oppositely directed outer surfaces between a pair of dies, at least one of which is formed with an array of bumps that taper outwardly toward a respective one of the outer surfaces. The bumps press into the one outer surface and form therein permanent cavities of a predetermined imprint depth so as to bond together the foils at the web region. A quality of seal is determined by measuring after formation of the cavities surface features of the cavities at a level of the one outer surface of the respective foil, and calculating based on the measured surface features an imprint depth of the cavity.

Abstract: Sealing tools are used in a machine in which foils are guided between two sealing tools that on their sides facing the foil have bumps with uniform relative spacing T. Compensation for the tolerances between the sealing tools and the foils is achieved for a defined penetration depth of the bumps into the foil workpiece. The spacing T of the bumps is predetermined, and subsequently an experimental measurement of the force ?DS is carried out that is necessary for the defined penetration depth of a test body of known geometry into the foils. Then, and with use of the force ?d applied by the sealing machine that is determined as the quotient of the forces applied to the sealing tools per surface unit of measure of the sealing tools, the corrugated surface A required for the defined penetration depth is set based on the relation A=?d*T2/?Ds.

Abstract: The method for producing a multi-day package containing various drugs has the following steps. A bottom layer is formed with a plurality of wells arranged in a pattern. A predetermined number of different drugs are arranged in predetermined positions at various dispensing stations of a filling device. The desired drugs are picked in a controlled manner from their predetermined positions at each dispensing station by at least one movable suction or gripper device, and the drugs are placed in predetermined wells. Finally, a sealing film is applied to the bottom layer to seal off the wells.

Abstract: The method for producing a multi-day package containing various drugs has the following steps: a bottom layer is formed with a plurality of wells arranged in a pattern; a predetermined number of different drugs is arranged in predetermined positions at various dispensing stations of a filling device; the desired number of drugs are picked in a controlled manner from their predetermined positions at each dispensing station by at least one movable suction or gripper device, and the drugs are deposited in the predetermined wells; and a sealing film is applied to the bottom layer to seal off the wells. In the course of this method, in at least one dispensing station several suction or gripper devices, which are arranged in correspondence with the pattern of the wells in the multi-day package and which travel parallel to each other, are actuated individually.

Abstract: In a sealing machine a pair of juxtaposed foils are sealed together at web regions having oppositely directed outer surfaces between a pair of dies, at least one of which is formed with an array of bumps that taper outwardly toward a respective one of the outer surfaces. The bumps press into the one outer surface and form therein permanent cavities of a predetermined imprint depth so as to bond together the foils at the web region. A quality of seal is determined by measuring after formation of the cavities surface features of the cavities at a level of the one outer surface of the respective foil, and calculating based on the measured surface features an imprint depth of the cavity.

Abstract: Sealing tools are used in a machine in which foils are guided between two sealing tools that on their sides facing the foil have bumps with uniform relative spacing T. Compensation for the tolerances between the sealing tools and the foils is achieved for a defined penetration depth of the bumps into the foil workpiece. The spacing T of the bumps is predetermined, and subsequently an experimental measurement of the force ?DS is carried out that is necessary for the defined penetration depth of a test body of known geometry into the foils. Then, and with use of the force ?d applied by the sealing machine that is determined as the quotient of the forces applied to the sealing tools per surface unit of measure of the sealing tools, the corrugated surface A required for the defined penetration depth is set based on the relation A=?d*T2/?Ds.

Abstract: Sealing tools for use in a thermal sealing machine each have a plurality of ridges oriented to engage together on opposite sides of a plurality of thermally bondable foils with the tools at substantially different operating temperatures when engaged with the foils during a sealing operation. These tools are made by first manufacturing one of the tools to a predetermined ridge-to-ridge spacing and then ascertaining the ridge-to-ridge spacing of the one tool at the respective operating temperature. Then a difference between a ridge-to-ridge spacing of the other of the tools is calculated at a predetermined manufacturing temperature and the respective operating temperature. Finally the other tool is manufactured at the manufacturing temperature with a ridge-to-ridge spacing equal to the ridge-to-ridge spacing at the respective operating temperature minus the calculated difference.