Abstract: A sample support (100, 101, 102, . . . ), in particular for cryopreservation of biological samples, is described and includes: a holder part (10) with a sample receiving chamber (11), a retaining device (12, 13) on which a sample can be disposed, and support connecting elements (14, 15) which are directed at opposite holder part ends (16, 17) and are formed to fit together so that a plurality of holder parts (16) can be put together. A sample store (200), which includes an assemblage of a large number of such sample supports, and a method for the cryopreservation of biological samples, are also described.

Abstract: A cryopreservation storage device (100), in particular for cryopreservation of biological samples, comprises a plurality of multi sample modules (20) being adapted for accommodating the biological samples and sample memories, a module control device (30) controlling an access to sample memories accommodated by the multi sample modules (20), and a data interface (41) for accessing to the module control device (30), wherein the module control device (30) includes a data management processor (31), which can be controlled via the data interface (41). Furthermore, a cryopreservation apparatus including at least one cryopreservation storage device (100) and a method for cryopreservation of biological samples are described.

Abstract: A targeted cultivation phase adjustment is provided in a process for the cultivation of cells in which biological cells are cultivated on at least one boundary surface between different, non-solid cultivation phases so that pre-determined cultivation conditions are given. A cultivation apparatus (100) for biological cells is also provided that includes a culture container (10) with different, non-solid cultivation phases (20) between which at least one boundary surface is formed.

Abstract: The invention relates to an aquarium with a pressure-tight aquarium tank, which during operation is filled with a liquid, and with a pressure-resistant rising pipe, which opens out into the aquarium tank and is intended for producing an increased hydrostatic pressure in the aquarium tank by a liquid column located in the rising pipe.

Abstract: An adapter device includes a receptacle including at least one receiving element that detachably secures a sample chamber for cryoconservation of a biological sample, and a coupling device that connects the receptacle to a base section which can be secured in a cooling device, wherein the receiving element is 1) immobile in a holding state at a cryoconservation temperature and secures the sample chamber and 2) at least one of deformable and movable in a release state at a temperature above the cryoconservation temperature so that the sample chamber is detachable from the adapter device or can be inserted into the adapter device.

Abstract: A method for moving a probe (10, 91) through a cell material (20), which is formed from biological cells (21), is described, the probe (10) displacing the cells (21) without injury. A probe (10, 91) for performing the method and a cell manipulator, which is equipped with at least one probe of this type, are also described.

Abstract: A manipulation tool is disclosed for producing cell material having multiple biological cells, which have a predefined geometrical arrangement. The tool includes a tool body, whose surface at least partially contacts the cell material, and a setting device for adjusting the tool body by a continuous expansion, so that geometrical properties of the surface change and an interior of the tool body is enlarged. The setting device is adapted to expand the tool body at an advance velocity in a range from 0.1 ?m/h to 1 mm/h.

Abstract: An adapter device includes a receptacle including at least one receiving element that detachably secures a sample chamber for cryoconservation of a biological sample, and a coupling device that connects the receptacle to a base section which can be secured in a cooling device, wherein the receiving element is 1) immobile in a holding state at a cryoconservation temperature and secures the sample chamber and 2) at least one of deformable and movable in a release state at a temperature above the cryoconservation temperature so that the sample chamber is detachable from the adapter device or can be inserted into the adapter device.

Abstract: The invention relates to an aquarium with a pressure-tight aquarium tank (7-12), which during operation is filled with a liquid, and with a pressure-resistant rising pipe (1), which opens out into the aquarium tank (7-12) and is intended for producing an increased hydrostatic pressure in the aquarium tank (7-12) by a liquid column located in the rising pipe (1).

Abstract: A method for operating a cryostorage device (100), especially for biological samples, is described which comprises a sample carrier (10) to receive at least one sample (11) and a data storage (20), wherein data are inductively transmitted from the data storage device (20) into a wireless transmission channel (40) and/or conversely using a resonant circuit (30) connected to the data storage device (20).

Abstract: A manipulation tool is disclosed for producing cell material having multiple biological cells, which have a predefined geometrical arrangement. The tool includes a tool body, whose surface at least partially contacts the cell material, and a setting device for adjusting the tool body by a continuous expansion, so that geometrical properties of the surface change and an interior of the tool body is enlarged. The setting device is adapted to expand the tool body at an advance velocity in a range from 0.1 ?m/h to 1 mm/h.

Abstract: The invention relates to an aquarium with a water tank (2), filled with water (3) when in operation and containing objects for investigation (4, 19), in particularly biological organisms, said water tank (2) being at least partly located below ground in the earth (5). According to the invention, the water tank (2) runs so deep into the earth (5) that, at least the bottom of the water tank (2) is at the pressure of the deep sea. The invention further relates to a corresponding method of operation.

Abstract: A method for producing cell material (20) having multiple biological cells (21), which have a predefined geometrical arrangement, includes the steps of providing a manipulation tool (10) having a tool body (11), whose surface (12, 14) at least partially contacts the cell material (20), and adjusting the manipulation tool (10) using a change of geometrical properties of the surface (12, 14) in such a way that the geometrical arrangement of the cells (21) is changed. A manipulation tool for performing a method of this type is also described.

Abstract: The invention relates to an aquarium with a water tank (2), filled with water (3) when in operation and containing objects for investigation (4, 19), in particularly biological organisms, said water tank (2) being at least partly located below ground in the earth (5). According to the invention, the water tank (2) runs so deep into the earth (5) that, at least the bottom of the water tank (2) is at the pressure of the deep sea. The invention further relates to a corresponding method of operation.

Abstract: Substrates (100) are described for receiving a plurality of samples, especially for the preservation of biological samples at cryotemperatures comprising a plurality of substrate plates (11, 12, 13) arranged on top of one another as a stack (10) and comprising an anchoring axis (20) to which the substrate plates (11, 12, 13) are connected. Processes for the preservation of biological samples at cryotemperatures are also described.

Abstract: A sample support (100, 101, 102, . . . ), in particular for cryopreservation of biological samples, is described and includes: a holder part (10) with a sample receiving chamber (11), a retaining device (12, 13) on which a sample can be disposed, and support connecting elements (14, 15) which are directed at opposite holder part ends (16, 17) and are formed to fit together so that a plurality of holder parts (16) can be put together. A sample store (200), which includes an assemblage of a large number of such sample supports, and a method for the cryopreservation of biological samples, are also described.

Abstract: A targeted cultivation phase adjustment is provided in a process for the cultivation of cells in which biological cells are cultivated on at least one boundary surface between different, non-solid cultivation phases so that pre-determined cultivation conditions are given. A cultivation apparatus (100) for biological cells is also provided that includes a culture container (10) with different, non-solid cultivation phases (20) between which at least one boundary surface is formed.

Abstract: A cryopreservation storage device (100), in particular for cryopreservation of biological samples, comprises a plurality of multi sample modules (20) being adapted for accommodating the biological samples and sample memories, a module control device (30) controlling an access to sample memories accommodated by the multi sample modules (20), and a data interface (41) for accessing to the module control device (30), wherein the module control device (30) includes a data management processor (31), which can be controlled via the data interface (41). Furthermore, a cryopreservation apparatus including at least one cryopreservation storage device (100) and a method for cryopreservation of biological samples are described.

Abstract: A cell transfer method is described, in which transfer of at least one biological cell (21) describing a natural cell locomotion between a carrier (80) and a probe (10) is provided, and whereby positioning the probe (10) and the carrier (80) relative to one another in a transfer arrangement is provided, in which transfer of the cell (21) takes place due to the natural cell locomotion. Probes and cell manipulators for transferring biological cells are also described.