Patents by Inventor Guojing Sun

Guojing Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anthraquinone analogs and methods of making and using thereof
    Patent number: 10544090
    Abstract: Rhein analogues that exhibit anti-proliferative activity, particular against cancer cells, are described herein. In some embodiments, the compounds contain a flat or planar ring system. Such rings system by facilitate non-covalent binding of the compounds to the DNA complex, such as by intercalation. In some embodiment, the compounds contain a flat or planar ring system as described above and one or more substituents which are alkylating moieties, electrophilic groups or Michael acceptors or groups which contain one or more alkylating moieties, electrophilic groups and/or Michael acceptors. The compounds described herein can also contain one more functional groups to improve the solubility of the compounds.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: January 28, 2020
    Assignees: Georgia State University Research Foundation, Inc., Emory University, Children's Healthcare of Atlanta, Inc.
    Inventors: Binghe Wang, Chaofeng Dai, Alexander Draganov, Xiaochuan Yang, Guojing Sun, Chunhao Yang, Weixuan Chen, Nanting Ni, Muxiang Zhou, Lubing Gu
  • Curcumin analogs and methods of making and using thereof
    Patent number: 9884825
    Abstract: Compounds having Formula I or II, and methods of making and using thereof, are described herein:
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: February 6, 2018
    Assignees: Georgia State University Research Foundation, Inc., University of Delhi
    Inventors: Diwan S. Rawat, Binghe Wang, Nitin Kumar, Sunny Manohar, Xiaochuan Yang, Guojing Sun, Nanting Ni
  • Anthraquinone Analogs and Methods of Making and Using Thereof
    Publication number: 20150203442
    Abstract: Rhein analogues that exhibit anti-proliferative activity, particular against cancer cells, are described herein. In some embodiments, the compounds contain a flat or planar ring system. Such rings system by facilitate non-covalent binding of the compounds to the DNA complex, such as by intercalation. In some embodiment, the compounds contain a flat or planar ring system as described above and one or more substituents which are alkylating moieties, electrophilic groups or Michael acceptors or groups which contain one or more alkylating moieties, electrophilic groups and/or Michael acceptors. The compounds described herein can also contain one more functional groups to improve the solubility of the compounds.
    Type: Application
    Filed: July 10, 2013
    Publication date: July 23, 2015
    Inventors: Binghe Wang, Chaofeng Dai, Alexander Draganov, Xiaochuan Yang, Guojing Sun, Chunhao Yang, Weixuan Chen, Nanting Ni, Muxiang Zhou, Lubing Gu
  • Curcumin Analogs and Methods of Making and Using Thereof
    Publication number: 20150152056
    Abstract: Compounds having Formula I or II, and methods of making and using thereof, are described herein:
    Type: Application
    Filed: August 1, 2013
    Publication date: June 4, 2015
    Applicant: University of Delhi
    Inventors: Diwan S. Rawat, Binghe Wang, Nitin Kumar, Sunny Manohar, Xiaochuan Yang, Guojing Sun, Nanting Ni
  • Method for quantitative measurements of HDL-C and LDL-C
    Patent number: 8785146
    Abstract: The present invention relates to a method for direct measurement of high-density lipoprotein cholesterol. (HDL-C) or low-density lipoprotein cholesterol (LDL-C) based on a modified chemical precipitation method, wherein the improvements were made by optimizing the concentrations and proportions of potassium polyvinyl sulfate (PVSK) and polyethylene glycol methyl ether (PEGME) in such a way that the enzymatic reactions are completed before precipitation formations. The method in combination with certain surfactants showed good correlations with other direct methods used for HDL-C or LDL-C determinations.
    Type: Grant
    Filed: October 6, 2008
    Date of Patent: July 22, 2014
    Assignee: Beijing Strong Biotechnologies, Inc.
    Inventor: Guojing Sun
  • Method for quantitative measurements of HDL-C and LDL-C
    Publication number: 20090246807
    Abstract: The present invention relates to a method for direct measurement of high-density lipoprotein cholesterol. (HDL-C) or low-density lipoprotein cholesterol (LDL-C) based on a modified chemical precipitation method, wherein the improvements were made by optimizing the concentrations and proportions of potassium polyvinyl sulfate (PVSK) and polyethylene glycol methyl ether (PEGME) in such a way that the enzymatic reactions are completed before precipitation formations. The method in combination with certain surfactants showed good correlations with other direct methods used for HDL-C or LDL-C determinations.
    Type: Application
    Filed: October 6, 2008
    Publication date: October 1, 2009
    Inventor: Guojing Sun