Abstract: Provided are methods and compositions for providing one or more food item recommendations for an individual. Methods can include determining an individual set of conditions from an overall set of conditions for the individual. Methods also include generating recommendations involving consumption of food, supplement and/or ingredients to affect the one or more biological conditions.

Abstract: Provided herein are methods and systems for inferring biological age in a subject. The methods involve analyzing data from a microbiome and/or somatic cell transcriptome from a subject and executing a model that infers biological age.

Abstract: Provided herein are methods of generating models for predicting the glycemic response of an individual to consumption of a food or meal. The method involves collecting from a plurality of subjects, phenotypic data, ohmic data, and glycemic response data to foods or meals having a defined macronutrient profile. This data is then used to train a machine learning algorithm to create a model that predicts glycemic response of an individual to a food or meal based on the macro nutrient profile of the food or meal.

Abstract: Provided are methods and compositions for providing one or more food item recommendations for an individual. Methods can include determining an individual set of conditions from an overall set of conditions for the individual. Methods also include generating recommendations involving consumption of food, supplement and/or ingredients to affect the one or more biological conditions.

Abstract: Provided herein are methods of generating models for predicting the glycemic response of an individual to consumption of a food or meal. The method involves collecting from a plurality of subjects, phenotypic data, ohmic data, and glycemic response data to foods or meals having a defined macronutrient profile. This data is then used to train a machine learning algorithm to create a model that predicts glycemic response of an individual to a food or meal based on the macro nutrient profile of the food or meal.

Abstract: Provided are methods and compositions for providing one or more food item recommendations for an individual. Methods can include determining an individual set of conditions from an overall set of conditions for the individual. Methods also include generating recommendations involving consumption of food, supplement and/or ingredients to affect the one or more biological conditions.

Abstract: Provided are methods balancing a gut microbiome. Methods involve sequencing nucleic acids from a sample to determine quantifies or activities of microorganisms Sequence information is used to generate functional activity scores for functional categories. These scores can be actionable.

Abstract: Provided herein are systems and method for producing models that infer health scores for health metrics for a subject. A first model, using raw feature data derived from the subject, infers feature cluster scores for each of a plurality of feature clusters in a feature group. A second model, using the inferred feature cluster scores, infers a heath score for a health metric.

Abstract: A method and system of managing a relationship between a provider and a client. A project model, organization model and stakeholder model are generated. Based on the project, organization and stakeholder models, factors that influence the relationship between the provider and the client are defined. The factors are evaluated by receiving results of data mining artifact(s) of the project, surveying the provider and/or client with a role-based survey, and capturing experiences provided by the provider and/or client. A status of the relationship is proactively monitored based on the evaluated factors. Based on historical information about the relationship and based on the evaluated factors, the status of the relationship between the provider and the client is assessed.

Abstract: A method generates, based on an original business process comprising at least one component, a variant business process comprising at least one variation compared to the original business process. The method comprises the steps of developing a variant meta-model, representing the at least one variation, instantiating and verifying the developed variant meta-model portion to obtain a variant model, and implementing the variant model to generate the variant. The method also comprises developing a formalism for defining the at least one variation.

Abstract: A method computes a resiliency score of an entity by representing the entity as a set of components. The method determines interactions and relationships and can, in one embodiment, determine two types of relationships between the components to produce resiliency scores for the components. These two types of relationships comprise a dependency relationship (whether a first component depends on one or more additional components to function) and a substitution relationship (whether two or more components share some functionality, and whether the first component can be at least partially substituted for one or more additional components). The method computes and outputs an overall score representing a resiliency of the entity based on the scores of the components of the entity and relationships between the components.

Abstract: A method computes a resiliency score of an entity by representing the entity as a set of components. The method determines interactions and relationships and can, in one embodiment, determine two types of relationships between the components to produce resiliency scores for the components. These two types of relationships comprise a dependency relationship (whether a first component depends on one or more additional components to function) and a substitution relationship (whether two or more components share some functionality, and whether the first component can be at least partially substituted for one or more additional components). The method computes and outputs an overall score representing a resiliency of the entity based on the scores of the components of the entity and relationships between the components.

Abstract: A computer implemented method for scheduling time of a user for at least one event, the method includes selecting, for each event, at least one of a time slot and a set of constraints for a time period, wherein the set of constraints are selected from a plurality of constraints; entering at least one of the time slot and the set of constraints into a calendar of the user; and scheduling the time for the user according to the available time indicated in the calendar and at least one of the time slot and the set of constraints.

Abstract: A computer implemented method for scheduling time of a user for at least one event, the method includes selecting, for each event, at least one of a time slot and a set of constraints for a time period, wherein the set of constraints are selected from a plurality of constraints; entering at least one of the time slot and the set of constraints into a calendar of the user; and scheduling the time for the user according to the available time indicated in the calendar and at least one of the time slot and the set of constraints.

Abstract: A technique for optimizing published event message sequences destined for information subscribers in an information processing system. Subscribers specify event interpretation rules which map event message streams into states. The event interpretation rules are maintained elsewhere in the system in preparation for providing optimized, possibly shorter, event message streams to subscribers, sufficient to correctly update the states. If a subscriber temporarily loses access to its event message stream, the optimized event message stream is determined using a shortest path graph search technique between the states defined by the start and end of the missing portion of the stream. Optimizations to the shortest path graph search technique are disclosed for use when the event interpretation rule is in replacement form, in which estimator functions based on extended rules are employed.

Abstract: A facility is provided for implementing a content-based publish-subscribe system using a group-based multicast. The facility includes mapping all possible groups of the publish-subscribe system to a smaller number of multicast groups, wherein the smaller number of multicast groups include brokers and the brokers have consumers. The mapping includes clustering the brokers of the publish-subscribe system into C clusters of multicast groups, wherein each cluster of the C clusters has its own subset of multicast groups, and wherein C>1. The clustered multicast groups are then used to forward an event to consumers within the content-based publish-subscribe system by multicasting the event up to C times, each multicasting being to a different cluster of the C clusters.